Protein Name | prostaglandin G/H synthase 1 |
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Organism | Ovis aries |
Gene ID | 443551 |
Gene Symbol | PTGS1 |
UniProt | P05979 (PGH1_SHEEP) |
Relationships |
Total Number of functionally related compound(s) :
28
Total Number of Articles : 25 |
Description |
prostaglandin-endoperoxide synthase 1 |
Gene Summary |
This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. Based on its ability to function as both a cyclooxygenase and as a peroxidase, the encoded protein has been identified as a moonlighting protein. [provided by RefSeq, Jan 2014] |
synonyms |
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Properties | |