CPRiL

KCNIP3

potassium voltage-gated channel interacting protein 3

This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. Members of this family are small calcium binding proteins containing EF-hand-like domains. They are integral subunit components of native Kv4 channel complexes that may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The encoded protein also functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

• calsenilin
• A-type potassium channel modulatory protein 3
• DRE-antagonist modulator
Kv channel interacting protein 3, calsenilin
calsenilin, presenilin-binding protein, EF hand transcription factor
kv channel-interacting protein 3
potassium channel interacting protein 3
CSEN
DREAM
KCHIP3