| Protein Name | hydroxymethylglutaryl-CoA reductase (NADPH) HMG2 |
|---|---|
| Organism | Saccharomyces cerevisiae S288C |
| Gene ID | 851171 |
| Gene Symbol | HMG2 |
| UniProt | P12684 (HMDH2_YEAST) |
| Relationships |
Total Number of functionally related compound(s) :
23
Total Number of Articles : 23 |
Description |
hydroxymethylglutaryl-CoA reductase (NADPH) HMG2 |
| Gene Summary |
Enables hydroxymethylglutaryl-CoA reductase (NADPH) activity. Involved in ergosterol biosynthetic process. Located in endoplasmic reticulum membrane and nuclear envelope. Part of proteasome complex. Is active in endoplasmic reticulum. Human ortholog(s) of this gene implicated in several diseases, including attention deficit hyperactivity disorder; coronary artery disease (multiple); diabetes mellitus (multiple); muscular disease (multiple); and neurodegenerative disease (multiple). Orthologous to human HMGCR (3-hydroxy-3-methylglutaryl-CoA reductase). [provided by Alliance of Genome Resources, Jul 2025] |
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