Protein Name citron rho-interacting serine/threonine kinase
Organism Rattus norvegicus
Gene ID 83620
Gene Symbol

Cit

UniProt E9PSL7 (CTRO_RAT)
Relationships Total Number of functionally related compound(s) : 24
Total Number of Articles : 12
Description

citron rho-interacting serine/threonine kinase

Gene Summary

Enables scaffold protein binding activity. Involved in several processes, including G2/M transition of mitotic cell cycle; gamma-aminobutyric acid signaling pathway; and postsynapse organization. Located in several cellular components, including GABA-ergic synapse; cleavage furrow; and postsynaptic density. Used to study epilepsy and microcephaly. Biomarker of traumatic brain injury. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly 17 and primary microcephaly. Orthologous to human CIT (citron rho-interacting serine/threonine kinase). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • citron rho-interacting kinase
  • citron (rho-interacting, serine/threonine kinase 21)
  • citron Rho-interacting kinase
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Properties