| Protein Name | aconitase 2 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 50 |
| Gene Symbol | ACO2 |
| UniProt | Q99798 (ACON_HUMAN), A0A7I2V586 (A0A7I2V586_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
111
Total Number of Articles : 127 |
Description |
aconitase 2 |
| Gene Summary |
The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification. [provided by RefSeq, Jul 2008] |
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