| Protein Name | solute carrier family 1 member 2 |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 29482 |
| Gene Symbol | Slc1a2 |
| UniProt | P31596 (EAA2_RAT), Q8K5B5 (Q8K5B5_RAT), Q8R4I5 (Q8R4I5_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
299
Total Number of Articles : 511 |
Description |
solute carrier family 1 member 2 |
| Gene Summary |
Enables high-affinity L-glutamate transmembrane transporter activity. Involved in L-glutamate transmembrane transport; response to antibiotic; and response to ethanol. Located in several cellular components, including astrocyte projection; dendrite; and presynaptic membrane. Part of membrane protein complex. Used to study alcohol dependence and nicotine dependence. Biomarker of Alzheimer's disease; alcohol use disorder; and middle cerebral artery infarction. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 41. Orthologous to human SLC1A2 (solute carrier family 1 member 2). [provided by Alliance of Genome Resources, Jun 2025] |
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| Properties | |