| Protein Name | alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 131 |
| Gene Symbol | ADH7 |
| UniProt | P40394 (ADH7_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
35
Total Number of Articles : 88 |
Description |
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide |
| Gene Summary |
This gene encodes class IV alcohol dehydrogenase 7 mu or sigma subunit, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The enzyme encoded by this gene is inefficient in ethanol oxidation, but is the most active as a retinol dehydrogenase; thus it may participate in the synthesis of retinoic acid, a hormone important for cellular differentiation. The expression of this gene is much more abundant in stomach than liver, thus differing from the other known gene family members. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009] |
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