Protein Name transcription factor 12
Organism Homo sapiens
Gene ID 6938
Gene Symbol

TCF12

UniProt Q99081 (HTF4_HUMAN), A0A024R5T1 (A0A024R5T1_HUMAN), F5GY10 (F5GY10_HUMAN), A0A024R5Z0 (A0A024R5Z0_HUMAN)
Relationships Total Number of functionally related compound(s) : 51
Total Number of Articles : 30
Description

transcription factor 12

Gene Summary

The protein encoded by this gene is a member of the basic helix-loop-helix (bHLH) E-protein family that recognizes the consensus binding site (E-box) CANNTG. This encoded protein is expressed in many tissues, among them skeletal muscle, thymus, B- and T-cells, and may participate in regulating lineage-specific gene expression through the formation of heterodimers with other bHLH E-proteins. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]

synonyms
  • transcription factor 12
  • DNA-binding protein HTF4
  • E-box-binding protein
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Properties