Protein Name S100 calcium binding protein A8 (calgranulin A)
Organism Mus musculus
Gene ID 20201
Gene Symbol

S100a8

UniProt P27005 (S10A8_MOUSE), Q53X15 (Q53X15_MOUSE)
Relationships Total Number of functionally related compound(s) : 125
Total Number of Articles : 132
Description

S100 calcium binding protein A8 (calgranulin A)

Gene Summary

Predicted to enable calcium ion binding activity and calcium-dependent protein binding activity. Acts upstream of or within astrocyte development and positive regulation of peptide secretion. Predicted to be located in cytosol; extracellular space; and intermediate filament cytoskeleton. Predicted to be part of S100A8 complex and calprotectin complex. Predicted to be active in cytoplasm. Is expressed in several structures, including bone marrow; extraembryonic component; liver; mesometrium; and placenta. Human ortholog(s) of this gene implicated in myocarditis. Orthologous to human S100A8 (S100 calcium binding protein A8). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • protein S100-A8
  • MRP-8
  • S100 calcium-binding protein A8
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Properties