Protein Name decorin
Organism Mus musculus
Gene ID 13179
Gene Symbol


UniProt P28654 (PGS2_MOUSE), Q3UKR1 (Q3UKR1_MOUSE)
Relationships Total Number of functionally related compound(s) : 67
Total Number of Articles : 52


Gene Summary

This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family of proteins. The encoded preproprotein is proteolytically processed to generate a mature protein product, which is secreted into the extracellular space to regulate collagen fibril assembly. Homozygous knockout mice for this gene exhibit enhanced tumorigenesis in a liver cancer model, and defects in collagen fibrils, leading to weakened skin and tendons. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]

  • decorin
  • bone proteoglycan II
  • DC
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