| Protein Name | decorin |
|---|---|
| Organism | Mus musculus |
| Gene ID | 13179 |
| Gene Symbol | Dcn |
| UniProt | P28654 (PGS2_MOUSE), Q3UKR1 (Q3UKR1_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
67
Total Number of Articles : 52 |
Description |
decorin |
| Gene Summary |
This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family of proteins. The encoded preproprotein is proteolytically processed to generate a mature protein product, which is secreted into the extracellular space to regulate collagen fibril assembly. Homozygous knockout mice for this gene exhibit enhanced tumorigenesis in a liver cancer model, and defects in collagen fibrils, leading to weakened skin and tendons. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015] |
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| Properties | |