Protein Name | PPARG related coactivator 1 |
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Organism | Homo sapiens |
Gene ID | 23082 |
Gene Symbol | PPRC1 |
UniProt | Q5VV67 (PPRC1_HUMAN), E7EVG6 (E7EVG6_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
42
Total Number of Articles : 26 |
Description |
PPARG related coactivator 1 |
Gene Summary |
The protein encoded by this gene is similar to PPAR-gamma coactivator 1 (PPARGC1/PGC-1), a protein that can activate mitochondrial biogenesis in part through a direct interaction with nuclear respiratory factor 1 (NRF1). This protein has been shown to interact with NRF1. It is thought to be a functional relative of PPAR-gamma coactivator 1 that activates mitochondrial biogenesis through NRF1 in response to proliferative signals. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013] |
synonyms |
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Properties | |