Protein Name PPARG related coactivator 1
Organism Homo sapiens
Gene ID 23082
Gene Symbol

PPRC1

UniProt Q5VV67 (PPRC1_HUMAN), E7EVG6 (E7EVG6_HUMAN)
Relationships Total Number of functionally related compound(s) : 42
Total Number of Articles : 26
Description

PPARG related coactivator 1

Gene Summary

The protein encoded by this gene is similar to PPAR-gamma coactivator 1 (PPARGC1/PGC-1), a protein that can activate mitochondrial biogenesis in part through a direct interaction with nuclear respiratory factor 1 (NRF1). This protein has been shown to interact with NRF1. It is thought to be a functional relative of PPAR-gamma coactivator 1 that activates mitochondrial biogenesis through NRF1 in response to proliferative signals. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]

synonyms
  • peroxisome proliferator-activated receptor gamma coactivator-related protein 1
  • PGC-1-related coactivator
  • peroxisome proliferator-activated receptor gamma, coactivator-related 1
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Properties