CPRiL

Protein Name	FTO alpha-ketoglutarate dependent dioxygenase
Organism	Homo sapiens
Gene ID	79068
Gene Symbol	FTO
UniProt	Q9C0B1 (FTO_HUMAN), A0A1B0GTC5 (A0A1B0GTC5_HUMAN), B3KU60 (B3KU60_HUMAN), Q99770 (Q99770_HUMAN)
Relationships	Total Number of functionally related compound(s) : 528 Total Number of Articles : 667
Description	FTO alpha-ketoglutarate dependent dioxygenase
Gene Summary	This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. [provided by RefSeq, Jul 2011]
synonyms	alpha-ketoglutarate-dependent dioxygenase FTO AlkB homolog 9 U6 small nuclear RNA (2'-O-methyladenosine-N(6)-)-demethylase FTO U6 small nuclear RNA N(6)-methyladenosine-demethylase FTO fat mass and obesity associated fat mass and obesity-associated protein intragenic FTO exon 9 containing transcript m6A(m)-demethylase FTO mRNA (2'-O-methyladenosine-N(6)-)-demethylase FTO mRNA N(6)-methyladenosine demethylase FTO tRNA N1-methyl adenine demethylase FTO ALKBH9 BMIQ14 GDFD IFEX9 Click to show/hide the synonyms
Properties