Protein Name C-C motif chemokine receptor 4
Organism Homo sapiens
Gene ID 1233
Gene Symbol

CCR4

UniProt P51679 (CCR4_HUMAN), A0N0Q1 (A0N0Q1_HUMAN)
Relationships Total Number of functionally related compound(s) : 151
Total Number of Articles : 149
Description

C-C motif chemokine receptor 4

Gene Summary

The protein encoded by this gene belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. [provided by RefSeq, Jul 2008]

synonyms
  • C-C chemokine receptor type 4
  • C-C CKR-4
  • CCR-4
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Properties