Protein Name zinc finger CCCH-type containing, antiviral 1
Organism Homo sapiens
Gene ID 56829
Gene Symbol

ZC3HAV1

UniProt Q7Z2W4 (ZCCHV_HUMAN)
Relationships Total Number of functionally related compound(s) : 56
Total Number of Articles : 59
Description

zinc finger CCCH-type containing, antiviral 1

Gene Summary

This gene encodes a CCCH-type zinc finger protein. This antiviral protein inhibits viral replication by recruiting cellular RNA degradation machineries to degrade viral mRNAs. The encoded protein plays an important role in the innate immune response against multiple DNA and RNA viruses, including Ebola virus, HIV and SARS-CoV-2 (which causes COVID-19). [provided by RefSeq, Sep 2021]

synonyms
  • zinc finger CCCH-type antiviral protein 1
  • ADP-ribosyltransferase diphtheria toxin-like 13
  • inactive Poly [ADP-ribose] polymerase 13
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Properties