Protein Name deoxyribonuclease 1L3
Organism Homo sapiens
Gene ID 1776
Gene Symbol

DNASE1L3

UniProt Q13609 (DNSL3_HUMAN), A0A024R365 (A0A024R365_HUMAN)
Relationships Total Number of functionally related compound(s) : 52
Total Number of Articles : 38
Description

deoxyribonuclease 1L3

Gene Summary

This gene encodes a member of the deoxyribonuclease I family. The encoded protein hydrolyzes DNA, is not inhibited by actin, and mediates the breakdown of DNA during apoptosis. Mutations in this gene are a cause of systemic lupus erythematosus-16. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]

synonyms
  • deoxyribonuclease gamma
  • DNase I homolog protein 2
  • DNase I homolog protein DHP2
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Properties