Protein Name sterol O-acyltransferase 2
Organism Mus musculus
Gene ID 223920
Gene Symbol

Soat2

UniProt O88908 (SOAT2_MOUSE)
Relationships Total Number of functionally related compound(s) : 65
Total Number of Articles : 83
Description

sterol O-acyltransferase 2

Gene Summary

Enables sterol O-acyltransferase activity. Involved in positive regulation of intestinal cholesterol absorption. Acts upstream of or within cholesterol metabolic process and cholesterol storage. Located in membrane. Human ortholog(s) of this gene implicated in coronary artery disease and hepatocellular carcinoma. Orthologous to human SOAT2 (sterol O-acyltransferase 2). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • sterol O-acyltransferase 2
  • ACAT-2
  • acyl-CoA:cholesterol acyltransferase
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Properties