| Protein Name | slowpoke |
|---|---|
| Organism | Drosophila melanogaster |
| Gene ID | 42940 |
| Gene Symbol | slo |
| UniProt | Q03720 (SLO_DROME), A0A0B4KHT2 (A0A0B4KHT2_DROME), A0A0B4KGV3 (A0A0B4KGV3_DROME), A0A0B4KGZ3 (A0A0B4KGZ3_DROME), A0A0B4KI08 (A0A0B4KI08_DROME), E1JIV7 (E1JIV7_DROME), A0A0B4KHF8 (A0A0B4KHF8_DROME) |
| Relationships |
Total Number of functionally related compound(s) :
13
Total Number of Articles : 8 |
Description |
slowpoke |
| Gene Summary |
Enables calcium-activated potassium channel activity. Involved in several processes, including male courtship behavior, veined wing generated song production; negative regulation of neuromuscular synaptic transmission; and regulation of synaptic assembly at neuromuscular junction. Located in membrane; neuron projection; and neuronal cell body. Is expressed in several structures, including adult brain; adult head; embryonic/larval midgut; embryonic/larval neuromuscular junction; and pedunculus of adult mushroom body. Used to study alcohol use disorder; heart conduction disease; paroxysmal nonkinesigenic dyskinesia 3; substance-related disorder; and withdrawal disorder. Human ortholog(s) of this gene implicated in Alzheimer's disease; generalized epilepsy; paroxysmal nonkinesigenic dyskinesia 3; and spermatogenic failure 79. Orthologous to several human genes including KCNMA1 (potassium calcium-activated channel subfamily M alpha 1). [provided by Alliance of Genome Resources, Jun 2025] |
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| Properties | |