Protein Name growth hormone releasing hormone
Organism Mus musculus
Gene ID 14601
Gene Symbol

Ghrh

UniProt P16043 (SLIB_MOUSE), Q544X5 (Q544X5_MOUSE)
Relationships Total Number of functionally related compound(s) : 62
Total Number of Articles : 57
Description

growth hormone releasing hormone

Gene Summary

This gene encodes a hormone that has stimulatory effects on pituitary growth hormone synthesis and release, and somatotrope expansion. The encoded preproprotein undergoes proteolytic processing to generate the mature peptide that is secreted by hypothalamus. Mice lacking the encoded protein are deficient in the growth hormone, live longer and exhibit growth retardation, enhanced insulin sensitivity and increased xenobiotic metabolism. [provided by RefSeq, Jul 2016]

synonyms
  • somatoliberin
  • growth hormone-releasing factor
  • GRF
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Properties