Protein Name isoprenylcysteine carboxyl methyltransferase
Organism Homo sapiens
Gene ID 23463
Gene Symbol

ICMT

UniProt O60725 (ICMT_HUMAN), A0A024R4F6 (A0A024R4F6_HUMAN), B3KS61 (B3KS61_HUMAN)
Relationships Total Number of functionally related compound(s) : 75
Total Number of Articles : 59
Description

isoprenylcysteine carboxyl methyltransferase

Gene Summary

This gene encodes the third of three enzymes that posttranslationally modify isoprenylated C-terminal cysteine residues in certain proteins and target those proteins to the cell membrane. This enzyme localizes to the endoplasmic reticulum. Alternative splicing may result in other transcript variants, but the biological validity of those transcripts has not been determined. [provided by RefSeq, Jul 2008]

synonyms
  • protein-S-isoprenylcysteine O-methyltransferase
  • prenylated protein carboxyl methyltransferase
  • prenylcysteine carboxyl methyltransferase
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Properties