Protein Name heterogeneous nuclear ribonucleoprotein A1
Organism Homo sapiens
Gene ID 3178
Gene Symbol


UniProt P09651 (ROA1_HUMAN), A0A024RAZ7 (A0A024RAZ7_HUMAN), A0A024RB53 (A0A024RB53_HUMAN)
Relationships Total Number of functionally related compound(s) : 142
Total Number of Articles : 141

heterogeneous nuclear ribonucleoprotein A1

Gene Summary

This gene encodes a member of a family of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs), which are RNA-binding proteins that associate with pre-mRNAs in the nucleus and influence pre-mRNA processing, as well as other aspects of mRNA metabolism and transport. The protein encoded by this gene is one of the most abundant core proteins of hnRNP complexes and plays a key role in the regulation of alternative splicing. Mutations in this gene have been observed in individuals with amyotrophic lateral sclerosis 20. Multiple alternatively spliced transcript variants have been found. There are numerous pseudogenes of this gene distributed throughout the genome. [provided by RefSeq, Feb 2016]

  • heterogeneous nuclear ribonucleoprotein A1
  • epididymis secretory sperm binding protein
  • helix-destabilizing protein
Click to show/hide the synonyms