Protein Name dynamin-related GTPase MGM1
Organism Saccharomyces cerevisiae S288C
Gene ID 854386
Gene Symbol

MGM1

UniProt P32266 (MGM1_YEAST)
Relationships Total Number of functionally related compound(s) : 8
Total Number of Articles : 12
Description

dynamin-related GTPase MGM1

Gene Summary

Enables GTPase activity and phospholipid binding activity. Involved in heme transport and mitochondrion organization. Located in mitochondrial crista; mitochondrial intermembrane space; and mitochondrial outer membrane. Is active in mitochondrial inner boundary membrane. Used to study Behr syndrome; dominant optic atrophy plus syndrome; mitochondrial DNA depletion syndrome 14; mitochondrial encephalomyopathy; and optic atrophy 1. Human ortholog(s) of this gene implicated in Behr syndrome; dominant optic atrophy plus syndrome; mitochondrial DNA depletion syndrome 14; optic atrophy; and optic atrophy 1. Orthologous to human OPA1 (OPA1 mitochondrial dynamin like GTPase). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • dynamin-related GTPase MGM1
  • YOR211C
  • MNA1
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Properties