Protein Name PROP paired-like homeobox 1
Organism Homo sapiens
Gene ID 5626
Gene Symbol

PROP1

UniProt O75360 (PROP1_HUMAN), A0A0G2JQ02 (A0A0G2JQ02_HUMAN)
Relationships Total Number of functionally related compound(s) : 157
Total Number of Articles : 89
Description

PROP paired-like homeobox 1

Gene Summary

This gene encodes a paired-like homeodomain transcription factor in the developing pituitary gland. Expression occurs prior to and is required for expression of pou domain transcription factor 1, which is responsible for pituitary development and hormone expression. Mutations in this gene have been associated with combined pituitary hormone deficiency-2 as well as deficiencies in luteinizing hormone, follicle-stimulating hormone, growth hormone, prolactin, and thyroid-stimulating hormone. [provided by RefSeq, Sep 2011]

synonyms
  • homeobox protein prophet of Pit-1
  • pituitary-specific homeodomain factor
  • prophet of Pit1, paired-like homeodomain transcription factor
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Properties