CPRiL

Ngfr

nerve growth factor receptor (TNFR superfamily, member 16)

Enables death receptor activity; nerve growth factor binding activity; and small GTPase binding activity. Involved in several processes, including circadian regulation of gene expression; dorsal aorta development; and intracellular glucose homeostasis. Acts upstream of or within several processes, including hair follicle morphogenesis; nervous system development; and regulation of signal transduction. Located in several cellular components, including cell surface; cell-cell junction; and postsynaptic density. Is active in neuromuscular junction. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Used to study Alzheimer's disease. Human ortholog(s) of this gene implicated in Alzheimer's disease and depressive disorder. Orthologous to human NGFR (nerve growth factor receptor). [provided by Alliance of Genome Resources, Jul 2025]

• tumor necrosis factor receptor superfamily member 16
• NGF receptor
• low affinity neurotrophin receptor p75NTR
low-affinity nerve growth factor receptor
low-affinity nerve growth factor receptor p75NGFR
low-affinity nerve growth factor receptor p75NGR
p75 neurotrophin receptor
LNGFR
Tnfrsf16
p75
p75NGFR
p75NTR