| Protein Name | apelin |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 8862 |
| Gene Symbol | APLN |
| UniProt | Q9ULZ1 (APEL_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
167
Total Number of Articles : 191 |
Description |
apelin |
| Gene Summary |
This gene encodes a peptide that functions as an endogenous ligand for the G-protein coupled apelin receptor. The encoded preproprotein is proteolytically processed into biologically active C-terminal peptide fragments. These peptide fragments activate different tissue specific signaling pathways that regulate diverse biological functions including fluid homeostasis, cardiovascular function and insulin secretion. This protein also functions as a coreceptor for the human immunodeficiency virus 1. [provided by RefSeq, Feb 2016] |
| synonyms |
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| Properties | |