Protein Name ATPase plasma membrane Ca2+ transporting 2
Organism Rattus norvegicus
Gene ID 24215
Gene Symbol

Atp2b2

UniProt P11506 (AT2B2_RAT)
Relationships Total Number of functionally related compound(s) : 26
Total Number of Articles : 26
Description

ATPase plasma membrane Ca2+ transporting 2

Gene Summary

Enables several functions, including ATP binding activity; P-type calcium transporter activity; and PDZ domain binding activity. Involved in neural retina development. Located in apical plasma membrane; dendritic spine membrane; and neuronal cell body membrane. Is active in several cellular components, including GABA-ergic synapse; parallel fiber to Purkinje cell synapse; and synaptic membrane. Biomarker of brain infarction. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 82 and autosomal recessive nonsyndromic deafness 12. Orthologous to human ATP2B2 (ATPase plasma membrane Ca2+ transporting 2). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • plasma membrane calcium-transporting ATPase 2
  • ATPase, Ca++ transporting, plasma membrane 2
  • plasma membrane Ca++-ATPase
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Properties