SCF E2 ubiquitin-protein ligase catalytic subunit CDC34 ; Saccharomyces cerevisiae S288C






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1 1748683 A site-directed approach for constructing temperature-sensitive ubiquitin-conjugating enzymes reveals a cell cycle function and growth function for RAD6. J Biol Chem 1991 Dec 15 1
2 7721857 Increased ubiquitin expression suppresses the cell cycle defect associated with the yeast ubiquitin conjugating enzyme, CDC34 (UBC3). Evidence for a noncovalent interaction between CDC34 and ubiquitin. J Biol Chem 1995 Apr 21 3
3 7862115 Novel CDC34 (UBC3) ubiquitin-conjugating enzyme mutants obtained by charge-to-alanine scanning mutagenesis. Mol Cell Biol 1995 Mar 3
4 8383676 The bacterially expressed yeast CDC34 gene product can undergo autoubiquitination to form a multiubiquitin chain-linked protein. J Biol Chem 1993 Mar 15 12
5 9461595 An essential domain within Cdc34p is required for binding to a complex containing Cdc4p and Cdc53p in Saccharomyces cerevisiae. J Biol Chem 1998 Feb 13 1
6 9499404 Cdc53 is a scaffold protein for multiple Cdc34/Skp1/F-box proteincomplexes that regulate cell division and methionine biosynthesis in yeast. Genes Dev 1998 Mar 1 1
7 10747049 Glucose and ras activity influence the ubiquitin ligases APC/C and SCF in Saccharomyces cerevisiae. Genetics 2000 Apr 1
8 11901211 Overexpression of the ubiquitin-conjugating enzyme Cdc34 confers resistance to methylmercury in Saccharomyces cerevisiae. Mol Pharmacol 2002 Apr 2
9 12037680 CK2-dependent phosphorylation of the E2 ubiquitin conjugating enzyme UBC3B induces its interaction with beta-TrCP and enhances beta-catenin degradation. Oncogene 2002 Jun 6 1
10 12406228 Glutathione regulates the expression of gamma-glutamylcysteine synthetase via the Met4 transcription factor. Mol Microbiol 2002 Oct 3
11 12498317 Investigation of intracellular factors involved in methylmercury toxicity. Tohoku J Exp Med 2002 Feb 1
12 12861024 Cdc34 self-association is facilitated by ubiquitin thiolester formation and is required for its catalytic activity. Mol Cell Biol 2003 Aug 1
13 13678584 Release of ubiquitin-charged Cdc34-S - Ub from the RING domain is essential for ubiquitination of the SCF(Cdc4)-bound substrate Sic1. Cell 2003 Sep 5 1
14 16112084 The ubiquitin ligase SCF(Grr1) is required for Gal2p degradation in the yeast Saccharomyces cerevisiae. Biochem Biophys Res Commun 2005 Oct 7 1
15 16952051 Control of methionine biosynthesis genes by protein kinase CK2-mediated phosphorylation of Cdc34. Cell Mol Life Sci 2006 Sep 1
16 17028344 The Cdc34/SCF ubiquitination complex mediates Saccharomyces cerevisiae cell wall integrity. Genetics 2006 Dec 1
17 17163635 From loops to chains: unraveling the mysteries of polyubiquitin chain specificity and processivity. ACS Chem Biol 2006 Feb 17 1
18 17329932 Ubiquitin-proteasome system as a factor that determine the sensitivity to methylmercury. Yakugaku Zasshi 2007 Mar 1
19 17461777 Cdc34 C-terminal tail phosphorylation regulates Skp1/cullin/F-box (SCF)-mediated ubiquitination and cell cycle progression. Biochem J 2007 Aug 1 6
20 17562869 SCF E3-mediated autoubiquitination negatively regulates activity of Cdc34 E2 but plays a nonessential role in the catalytic cycle in vitro and in vivo. Mol Cell Biol 2007 Aug 2
21 17904100 Ubiquitin-conjugating enzyme Cdc34 mediates cadmium resistance in budding yeast through ubiquitination of the transcription factor Met4. Biochem Biophys Res Commun 2007 Nov 23 7
22 18418079 The CK2 phosphorylation of catalytic domain of Cdc34 modulates its activity at the G1 to S transition in Saccharomyces cerevisiae. Cell Cycle 2008 May 15 1
23 18466927 The ubiquitin-conjugating enzymes, Ubc4 and Cdc34, mediate cadmium resistance in budding yeast through different mechanisms. Life Sci 2008 Jun 6 4
24 20194622 Molecular basis for lysine specificity in the yeast ubiquitin-conjugating enzyme Cdc34. Mol Cell Biol 2010 May 2
25 22949505 Oxidative stress responses involve oxidation of a conserved ubiquitin pathway enzyme. Mol Cell Biol 2012 Nov 2
26 29721631 Multiple chemo-genetic interactions between a toxic metabolite and the ubiquitin pathway in yeast. Curr Genet 2018 Dec 1