monoglyceride lipase ; Rattus norvegicus






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1 222330 Ethanediol monoester hydrolysis by monoacylglycerol lipase of rat liver microsomes. Biochim Biophys Acta 1979 Apr 27 4
2 665358 Identification and some characteristics of the enzyme protein of the hormone-sensitive lipase from rat adipose tissue. Adv Exp Med Biol 1978 1
3 698245 Enzymes catalyzing the hydrolysis of long-chain monoacyglycerols in rat adipose tissue. Biochim Biophys Acta 1978 Sep 28 4
4 889853 Purification and characterization of rat liver microsomal monoacylglycerol lipase in comparison to the other esterases. Biochim Biophys Acta 1977 Jul 20 7
5 1637859 Diacylglycerol metabolism in neonatal rat liver: characterization of cytosolic diacylglycerol lipase activity and its activation by monoalkylglycerols. Biochim Biophys Acta 1992 Jun 26 1
6 1910356 Changes in lipid metabolites and enzymes in rat brain due to ischemia and recirculation. Mol Chem Neuropathol 1991 Feb 1
7 2039549 Effect of ethanol intake on lipoprotein lipase activity in rat heart. Biochem Pharmacol 1991 Jun 15 3
8 2344437 Diacylglycerol generated in the phospholipid vesicles by phospholipase C is effectively utilized by diacylglycerol lipase in rat liver cytosol. Biochim Biophys Acta 1990 May 22 3
9 2598628 Lipoprotein lipase in rat heart--I. Characterization of tri-, di- and monoacylglycerol lipase activities in post-heparin effluents. Comp Biochem Physiol B 1989 1
10 2598634 Lipoprotein lipase in rat heart--III. Effects of sex steroid hormones on tri-, di- and monoacylglycerol lipase activities in post-heparin effluents. Comp Biochem Physiol B 1989 3
11 3190882 Monoacylglycerol lipase activity in cardiac myocytes. Biochem Cell Biol 1988 Sep 3
12 5947037 Partial purification of monoglyceride lipase from adipose tissue. J Lipid Res 1966 Mar 5
13 6100509 Monoacylglycerol lipase. Regulation and increased activity during hypoxia and ischemia. Neurochem Pathol 1984 Summer 3
14 7138892 Effects of antimalarial drugs on several rat-liver lysosomal enzymes involved in phosphatidylethanolamine catabolism. Biochim Biophys Acta 1982 Oct 14 2
15 9200468 NKR-P1A stimulation of arachidonate-generating enzymes in rat NK cells is associated with granule release and cytotoxic activity. J Immunol 1997 Jul 1 1
16 10357431 The mother rat's vomeronasal organ is involved in detection of dodecyl propionate, the pup's preputial gland pheromone. Physiol Behav 1999 May 1
17 10733881 Expression, purification, and characterization of histidine-tagged mouse monoglyceride lipase from baculovirus-infected insect cells. Protein Expr Purif 2000 Apr 1
18 12136125 Brain monoglyceride lipase participating in endocannabinoid inactivation. Proc Natl Acad Sci U S A 2002 Aug 6 9
19 12505697 A role for monoglyceride lipase in 2-arachidonoylglycerol inactivation. Chem Phys Lipids 2002 Dec 31 6
20 15013854 Monoglyceride lipase-like enzymatic activity is responsible for hydrolysis of 2-arachidonoylglycerol in rat cerebellar membranes. Biochem Pharmacol 2004 Apr 1 2
21 15095014 Differential diurnal variations of anandamide and 2-arachidonoyl-glycerol levels in rat brain. Cell Mol Life Sci 2004 Apr 1
22 15233753 Segregation of two endocannabinoid-hydrolyzing enzymes into pre- and postsynaptic compartments in the rat hippocampus, cerebellum and amygdala. Eur J Neurosci 2004 Jul 4
23 15272052 RNA interference suggests a primary role for monoacylglycerol lipase in the degradation of the endocannabinoid 2-arachidonoylglycerol. Mol Pharmacol 2004 Nov 9
24 15895107 Inhibition of fatty acid amide hydrolase and monoacylglycerol lipase by the anandamide uptake inhibitor VDM11: evidence that VDM11 acts as an FAAH substrate. Br J Pharmacol 2005 Aug 4
25 15975510 Characterization of the sulfhydryl-sensitive site in the enzyme responsible for hydrolysis of 2-arachidonoyl-glycerol in rat cerebellar membranes. Chem Biol 2005 Jun 12
26 16316669 Endocannabinoids at the spinal level regulate, but do not mediate, nonopioid stress-induced analgesia. Neuropharmacology 2006 Mar 3
27 16466961 Development of the first potent and specific inhibitors of endocannabinoid biosynthesis. Biochim Biophys Acta 2006 Feb 8
28 16906479 PPARgamma agonism increases rat adipose tissue lipolysis, expression of glyceride lipases, and the response of lipolysis to hormonal control. Diabetologia 2006 Oct 2
29 16931330 URB754 has no effect on the hydrolysis or signaling capacity of 2-AG in the rat brain. Chem Biol 2006 Aug 4
30 17143303 Lack of selectivity of URB602 for 2-oleoylglycerol compared to anandamide hydrolysis in vitro. Br J Pharmacol 2007 Jan 3
31 17179944 The antinociceptive effects of intraplantar injections of 2-arachidonoyl glycerol are mediated by cannabinoid CB2 receptors. Br J Pharmacol 2007 Mar 2
32 17245358 Endothelium-dependent metabolism by endocannabinoid hydrolases and cyclooxygenases limits vasorelaxation to anandamide and 2-arachidonoylglycerol. Br J Pharmacol 2007 Mar 12
33 17592505 Interaction of ligands for the peroxisome proliferator-activated receptor gamma with the endocannabinoid system. Br J Pharmacol 2007 Aug 1
34 17910610 Therapeutic potential of endocannabinoid-hydrolysing enzyme inhibitors. Basic Clin Pharmacol Toxicol 2007 Nov 10
35 18096504 URB602 inhibits monoacylglycerol lipase and selectively blocks 2-arachidonoylglycerol degradation in intact brain slices. Chem Biol 2007 Dec 14
36 18234185 Bidirectional roles of the brain 2-arachidonoyl-sn-glycerol in the centrally administered vasopressin-induced adrenomedullary outflow in rats. Eur J Pharmacol 2008 Mar 17 3
37 18452279 Full mass spectrometric characterization of human monoacylglycerol lipase generated by large-scale expression and single-step purification. J Proteome Res 2008 May 5
38 18695638 Modulation of the anti-nociceptive effects of 2-arachidonoyl glycerol by peripherally administered FAAH and MGL inhibitors in a neuropathic pain model. Br J Pharmacol 2008 Nov 1
39 18816788 Differential alteration of hippocampal excitatory synaptic transmission by cannabinoid ligands. J Neurosci Res 2009 Feb 15 1
40 19486005 A critical cysteine residue in monoacylglycerol lipase is targeted by a new class of isothiazolinone-based enzyme inhibitors. Br J Pharmacol 2009 Jul 14
41 19666749 Blockade of 2-arachidonoylglycerol hydrolysis by selective monoacylglycerol lipase inhibitor 4-nitrophenyl 4-(dibenzo[d][1,3]dioxol-5-yl(hydroxy)methyl)piperidine-1-carboxylate (JZL184) Enhances retrograde endocannabinoid signaling. J Pharmacol Exp Ther 2009 Nov 1
42 19691145 Age-related changes in the metabolization of phosphatidic acid in rat cerebral cortex synaptosomes. Arch Biochem Biophys 2009 Aug 15 7
43 20085790 Fructose affects enzymes involved in the synthesis and degradation of hypothalamic endocannabinoids. Regul Pept 2010 Apr 9 1
44 20143779 Synthesis and evaluation of paracetamol esters as novel fatty acid amide hydrolase inhibitors. J Med Chem 2010 Mar 11 2
45 20416378 Inhibitors of monoacylglycerol lipase, fatty-acid amide hydrolase and endocannabinoid transport differentially suppress capsaicin-induced behavioral sensitization through peripheral endocannabinoid mechanisms. Pharmacol Res 2010 Sep 11
46 20599824 Early maternal deprivation induces changes on the expression of 2-AG biosynthesis and degradation enzymes in neonatal rat hippocampus. Brain Res 2010 Aug 19 1
47 20727980 The endocannabinoid 2-arachidonoylglycerol (2-AG) and metabolizing enzymes during rat fetoplacental development: a role in uterine remodelling. Int J Biochem Cell Biol 2010 Nov 1
48 20735405 Inhibition of monoacylglycerol lipase by troglitazone, N-arachidonoyl dopamine and the irreversible inhibitor JZL184: comparison of two different assays. Br J Pharmacol 2010 Dec 2
49 21198549 Peripheral antinociceptive effects of inhibitors of monoacylglycerol lipase in a rat model of inflammatory pain. Br J Pharmacol 2011 Aug 9
50 21371452 Endogenously generated 2-arachidonoylglycerol plays an inhibitory role in bombesin-induced activation of central adrenomedullary outflow in rats. Eur J Pharmacol 2011 May 11 3