1 | 1411543 | Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E. | Science | 1992 Oct 16 |
1 |
2 | 1512507 | Expression of human apolipoprotein E but not that of apolipoprotein A-I by mouse C127 cells is associated with increased secretion of lipids in the form of vesicles and discs. | J Lipid Res | 1992 Jun |
6 |
3 | 1542669 | Overexpression of apolipoprotein E in transgenic mice: marked reduction in plasma lipoproteins except high density lipoprotein and resistance against diet-induced hypercholesterolemia. | Proc Natl Acad Sci U S A | 1992 Mar 1 |
2 |
4 | 1657949 | Suppression of cAMP-mediated signal transduction in mouse adrenocortical cells which express apolipoprotein E. | J Biol Chem | 1991 Nov 5 |
3 |
5 | 1998641 | Cholesterol accumulation in J774 macrophages induced by triglyceride-rich lipoproteins. Comparison of very low density lipoprotein from subjects with type III, IV, and V hyperlipoproteinemias. | Arterioscler Thromb | 1991 Mar-Apr |
5 |
6 | 2072040 | Regulation of apolipoprotein E secretion by high density lipoprotein 3 in mouse macrophages. | J Lipid Res | 1991 May |
9 |
7 | 2477479 | Synthesis and secretion of apoE in thioglycolate-elicited mouse peritoneal macrophages: effect of cholesterol efflux. | J Lipid Res | 1989 Jun |
12 |
8 | 2754339 | A potential complication in the use of monoclonal antibodies: inhibition of apoB-mediated receptor binding by an anti-apoE antibody. | J Lipid Res | 1989 Apr |
1 |
9 | 2794789 | Regulation of macrophage apolipoprotein E gene expression by cholesterol. | J Lipid Res | 1989 Jul |
2 |
10 | 2995353 | Obligatory role of cholesterol and apolipoprotein E in the formation of large cholesterol-enriched and receptor-active high density lipoproteins. | J Biol Chem | 1985 Oct 5 |
4 |
11 | 3029073 | The molecular basis of a familial apoE deficiency. An acceptor splice site mutation in the third intron of the deficient apoE gene. | J Biol Chem | 1987 Feb 15 |
1 |
12 | 3468509 | Expression of the murine apolipoprotein E gene is coupled to the differentiated state of F9 embryonal carcinoma cells. | Proc Natl Acad Sci U S A | 1987 Feb |
3 |
13 | 3624230 | Macrophage free cholesterol content regulates apolipoprotein E synthesis. | J Biol Chem | 1987 Aug 25 |
10 |
14 | 3733751 | Uptake of canine beta-very low density lipoproteins by mouse peritoneal macrophages is mediated by a low density lipoprotein receptor. | J Biol Chem | 1986 Aug 25 |
3 |
15 | 3844438 | Factor B, the complement alternative pathway serine proteinase, is a major constitutive protein synthesized and secreted by resident and elicited mouse macrophages. | J Exp Med | 1985 Feb 1 |
1 |
16 | 3865219 | Evolution of apolipoprotein E: mouse sequence and evidence for an 11-nucleotide ancestral unit. | Proc Natl Acad Sci U S A | 1985 Dec |
2 |
17 | 6198420 | Modulation of apoprotein E secretion in response to receptor-mediated endocytosis in resident and inflammatory macrophages. | J Exp Med | 1984 Jan 1 |
6 |
18 | 6343371 | Formation of cholesterol- and apoprotein E-enriched high density lipoproteins in vitro. | J Biol Chem | 1983 May 25 |
1 |
19 | 6350291 | Endotoxin suppresses expression of apoprotein E by mouse macrophages in vivo and in culture. A biochemical and genetic study. | J Biol Chem | 1983 Sep 10 |
1 |
20 | 6619735 | Apoprotein E is synthesized and secreted by resident and thioglycollate-elicited macrophages but not by pyran copolymer- or bacillus Calmette-Guerin-activated macrophages. | J Exp Med | 1983 Oct 1 |
7 |
21 | 6950395 | Mouse macrophages synthesize and secrete a protein resembling apolipoprotein E. | Proc Natl Acad Sci U S A | 1981 Dec |
4 |
22 | 7499399 | Intracellular localization and metabolism of chylomicron remnants in the livers of low density lipoprotein receptor-deficient mice and apoE-deficient mice. Evidence for slow metabolism via an alternative apoE-dependent pathway. | J Biol Chem | 1995 Dec 1 |
1 |
23 | 7511933 | ApoE-deficient mice are a model of lipoprotein oxidation in atherogenesis. Demonstration of oxidation-specific epitopes in lesions and high titers of autoantibodies to malondialdehyde-lysine in serum. | Arterioscler Thromb | 1994 Apr |
1 |
24 | 7581381 | Inactivation of Apoe and Apoc1 by two consecutive rounds of gene targeting: effects on mRNA expression levels of gene cluster members. | Hum Mol Genet | 1995 Aug |
1 |
25 | 7583527 | Estrogen-induced alterations in lipoprotein metabolism in autoimmune MRL/lpr mice. | Arterioscler Thromb Vasc Biol | 1995 Oct |
1 |
26 | 7583536 | Effect of the antioxidant N,N'-diphenyl 1,4-phenylenediamine (DPPD) on atherosclerosis in apoE-deficient mice. | Arterioscler Thromb Vasc Biol | 1995 Oct |
2 |
27 | 7592957 | Stable expression and secretion of apolipoproteins E3 and E4 in mouse neuroblastoma cells produces differential effects on neurite outgrowth. | J Biol Chem | 1995 Nov 10 |
1 |
28 | 7605370 | Failure of exogenous apoprotein E-3 to enhance cholesterol egress from J-774 murine macrophages in culture. | Atherosclerosis | 1995 Apr 7 |
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29 | 7657831 | Apolipoprotein E deficiency in mice: gene replacement and prevention of atherosclerosis using adenovirus vectors. | J Clin Invest | 1995 Sep |
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30 | 7666000 | In vivo cholesterol kinetics in apolipoprotein E-deficient and control mice. | J Lipid Res | 1995 Jun |
3 |
31 | 7667279 | Decreased atherosclerosis in mice deficient in both macrophage colony-stimulating factor (op) and apolipoprotein E. | Proc Natl Acad Sci U S A | 1995 Aug 29 |
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32 | 7729619 | Overexpression of apolipoprotein E prevents development of diabetic hyperlipidemia in transgenic mice. | Diabetes | 1995 May |
3 |
33 | 7772082 | Atypical xanthomatosis in apolipoprotein E-deficient mice after cholesterol feeding. | Atherosclerosis | 1995 Jan 20 |
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34 | 7798236 | Co-expression of cholesteryl ester transfer protein and defective apolipoprotein E in transgenic mice alters plasma cholesterol distribution. Implications for the pathogenesis of type III hyperlipoproteinemia. | J Biol Chem | 1994 Dec 23 |
2 |
35 | 7798939 | Nerve regeneration and cholesterol reutilization occur in the absence of apolipoproteins E and A-I in mice. | J Neurochem | 1995 Jan |
2 |
36 | 7802634 | Role of HDL apolipoprotein E in cellular cholesterol efflux: studies in apo E knockout transgenic mice. | Biochem Biophys Res Commun | 1994 Dec 15 |
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37 | 7860728 | Inhibition of diet-induced atheroma formation in transgenic mice expressing apolipoprotein E in the arterial wall. | J Clin Invest | 1995 Feb |
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38 | 7863332 | Prevention of atherosclerosis in apolipoprotein E-deficient mice by bone marrow transplantation. | Science | 1995 Feb 17 |
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39 | 7921790 | The mouse plasma PAF acetylhydrolase: II. It consists of two enzymes both associated with the HDL. | J Lipid Mediat Cell Signal | 1994 May |
2 |
40 | 7937814 | Human apolipoprotein A-I gene expression increases high density lipoprotein and suppresses atherosclerosis in the apolipoprotein E-deficient mouse. | Proc Natl Acad Sci U S A | 1994 Sep 27 |
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41 | 7964191 | Identification of apolipoprotein B-100 low density lipoproteins, apolipoprotein B-48 remnants, and apolipoprotein E-rich high density lipoproteins in the mouse. | J Lipid Res | 1994 Jul |
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42 | 7989859 | Expression of heterologous human apolipoprotein E by J774 macrophages enhances cholesterol efflux to HDL3. | J Lipid Res | 1994 Aug |
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43 | 8014576 | Altered lipoprotein metabolism in transgenic mice expressing low levels of a human receptor-binding-defective apolipoprotein E variant. | J Lipid Res | 1994 Mar |
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44 | 8024602 | Increased plasma and lipoprotein lipid peroxidation in apo E-deficient mice. | Biochem Biophys Res Commun | 1994 Jun 30 |
3 |
45 | 8040345 | Apolipoprotein AI transgene corrects apolipoprotein E deficiency-induced atherosclerosis in mice. | J Clin Invest | 1994 Aug |
2 |
46 | 8127890 | A plasma lipoprotein containing only apolipoprotein E and with gamma mobility on electrophoresis releases cholesterol from cells. | Proc Natl Acad Sci U S A | 1994 Mar 1 |
2 |
47 | 8163669 | Overexpression of apolipoprotein CII causes hypertriglyceridemia in transgenic mice. | J Clin Invest | 1994 Apr |
2 |
48 | 8182153 | Secretion-recapture process of apolipoprotein E in hepatic uptake of chylomicron remnants in transgenic mice. | J Clin Invest | 1994 May |
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49 | 8183926 | The two-receptor model of lipoprotein clearance: tests of the hypothesis in "knockout" mice lacking the low density lipoprotein receptor, apolipoprotein E, or both proteins. | Proc Natl Acad Sci U S A | 1994 May 10 |
2 |
50 | 8280184 | Exogenous glucocorticoids increase macrophage secretion of apo E by cholesterol-independent pathways. | Atherosclerosis | 1993 Oct |
18 |