apolipoprotein E ; Mus musculus






2921 Article(s)
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1 1411543 Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E. Science 1992 Oct 16 1
2 1512507 Expression of human apolipoprotein E but not that of apolipoprotein A-I by mouse C127 cells is associated with increased secretion of lipids in the form of vesicles and discs. J Lipid Res 1992 Jun 6
3 1542669 Overexpression of apolipoprotein E in transgenic mice: marked reduction in plasma lipoproteins except high density lipoprotein and resistance against diet-induced hypercholesterolemia. Proc Natl Acad Sci U S A 1992 Mar 1 2
4 1657949 Suppression of cAMP-mediated signal transduction in mouse adrenocortical cells which express apolipoprotein E. J Biol Chem 1991 Nov 5 3
5 1998641 Cholesterol accumulation in J774 macrophages induced by triglyceride-rich lipoproteins. Comparison of very low density lipoprotein from subjects with type III, IV, and V hyperlipoproteinemias. Arterioscler Thromb 1991 Mar-Apr 5
6 2072040 Regulation of apolipoprotein E secretion by high density lipoprotein 3 in mouse macrophages. J Lipid Res 1991 May 9
7 2477479 Synthesis and secretion of apoE in thioglycolate-elicited mouse peritoneal macrophages: effect of cholesterol efflux. J Lipid Res 1989 Jun 12
8 2754339 A potential complication in the use of monoclonal antibodies: inhibition of apoB-mediated receptor binding by an anti-apoE antibody. J Lipid Res 1989 Apr 1
9 2794789 Regulation of macrophage apolipoprotein E gene expression by cholesterol. J Lipid Res 1989 Jul 2
10 2995353 Obligatory role of cholesterol and apolipoprotein E in the formation of large cholesterol-enriched and receptor-active high density lipoproteins. J Biol Chem 1985 Oct 5 4
11 3029073 The molecular basis of a familial apoE deficiency. An acceptor splice site mutation in the third intron of the deficient apoE gene. J Biol Chem 1987 Feb 15 1
12 3468509 Expression of the murine apolipoprotein E gene is coupled to the differentiated state of F9 embryonal carcinoma cells. Proc Natl Acad Sci U S A 1987 Feb 3
13 3624230 Macrophage free cholesterol content regulates apolipoprotein E synthesis. J Biol Chem 1987 Aug 25 10
14 3733751 Uptake of canine beta-very low density lipoproteins by mouse peritoneal macrophages is mediated by a low density lipoprotein receptor. J Biol Chem 1986 Aug 25 3
15 3844438 Factor B, the complement alternative pathway serine proteinase, is a major constitutive protein synthesized and secreted by resident and elicited mouse macrophages. J Exp Med 1985 Feb 1 1
16 3865219 Evolution of apolipoprotein E: mouse sequence and evidence for an 11-nucleotide ancestral unit. Proc Natl Acad Sci U S A 1985 Dec 2
17 6198420 Modulation of apoprotein E secretion in response to receptor-mediated endocytosis in resident and inflammatory macrophages. J Exp Med 1984 Jan 1 6
18 6343371 Formation of cholesterol- and apoprotein E-enriched high density lipoproteins in vitro. J Biol Chem 1983 May 25 1
19 6350291 Endotoxin suppresses expression of apoprotein E by mouse macrophages in vivo and in culture. A biochemical and genetic study. J Biol Chem 1983 Sep 10 1
20 6619735 Apoprotein E is synthesized and secreted by resident and thioglycollate-elicited macrophages but not by pyran copolymer- or bacillus Calmette-Guerin-activated macrophages. J Exp Med 1983 Oct 1 7
21 6950395 Mouse macrophages synthesize and secrete a protein resembling apolipoprotein E. Proc Natl Acad Sci U S A 1981 Dec 4
22 7499399 Intracellular localization and metabolism of chylomicron remnants in the livers of low density lipoprotein receptor-deficient mice and apoE-deficient mice. Evidence for slow metabolism via an alternative apoE-dependent pathway. J Biol Chem 1995 Dec 1 1
23 7511933 ApoE-deficient mice are a model of lipoprotein oxidation in atherogenesis. Demonstration of oxidation-specific epitopes in lesions and high titers of autoantibodies to malondialdehyde-lysine in serum. Arterioscler Thromb 1994 Apr 1
24 7581381 Inactivation of Apoe and Apoc1 by two consecutive rounds of gene targeting: effects on mRNA expression levels of gene cluster members. Hum Mol Genet 1995 Aug 1
25 7583527 Estrogen-induced alterations in lipoprotein metabolism in autoimmune MRL/lpr mice. Arterioscler Thromb Vasc Biol 1995 Oct 1
26 7583536 Effect of the antioxidant N,N'-diphenyl 1,4-phenylenediamine (DPPD) on atherosclerosis in apoE-deficient mice. Arterioscler Thromb Vasc Biol 1995 Oct 2
27 7592957 Stable expression and secretion of apolipoproteins E3 and E4 in mouse neuroblastoma cells produces differential effects on neurite outgrowth. J Biol Chem 1995 Nov 10 1
28 7605370 Failure of exogenous apoprotein E-3 to enhance cholesterol egress from J-774 murine macrophages in culture. Atherosclerosis 1995 Apr 7 1
29 7657831 Apolipoprotein E deficiency in mice: gene replacement and prevention of atherosclerosis using adenovirus vectors. J Clin Invest 1995 Sep 1
30 7666000 In vivo cholesterol kinetics in apolipoprotein E-deficient and control mice. J Lipid Res 1995 Jun 3
31 7667279 Decreased atherosclerosis in mice deficient in both macrophage colony-stimulating factor (op) and apolipoprotein E. Proc Natl Acad Sci U S A 1995 Aug 29 1
32 7729619 Overexpression of apolipoprotein E prevents development of diabetic hyperlipidemia in transgenic mice. Diabetes 1995 May 3
33 7772082 Atypical xanthomatosis in apolipoprotein E-deficient mice after cholesterol feeding. Atherosclerosis 1995 Jan 20 1
34 7798236 Co-expression of cholesteryl ester transfer protein and defective apolipoprotein E in transgenic mice alters plasma cholesterol distribution. Implications for the pathogenesis of type III hyperlipoproteinemia. J Biol Chem 1994 Dec 23 2
35 7798939 Nerve regeneration and cholesterol reutilization occur in the absence of apolipoproteins E and A-I in mice. J Neurochem 1995 Jan 2
36 7802634 Role of HDL apolipoprotein E in cellular cholesterol efflux: studies in apo E knockout transgenic mice. Biochem Biophys Res Commun 1994 Dec 15 9
37 7860728 Inhibition of diet-induced atheroma formation in transgenic mice expressing apolipoprotein E in the arterial wall. J Clin Invest 1995 Feb 5
38 7863332 Prevention of atherosclerosis in apolipoprotein E-deficient mice by bone marrow transplantation. Science 1995 Feb 17 1
39 7921790 The mouse plasma PAF acetylhydrolase: II. It consists of two enzymes both associated with the HDL. J Lipid Mediat Cell Signal 1994 May 2
40 7937814 Human apolipoprotein A-I gene expression increases high density lipoprotein and suppresses atherosclerosis in the apolipoprotein E-deficient mouse. Proc Natl Acad Sci U S A 1994 Sep 27 1
41 7964191 Identification of apolipoprotein B-100 low density lipoproteins, apolipoprotein B-48 remnants, and apolipoprotein E-rich high density lipoproteins in the mouse. J Lipid Res 1994 Jul 1
42 7989859 Expression of heterologous human apolipoprotein E by J774 macrophages enhances cholesterol efflux to HDL3. J Lipid Res 1994 Aug 6
43 8014576 Altered lipoprotein metabolism in transgenic mice expressing low levels of a human receptor-binding-defective apolipoprotein E variant. J Lipid Res 1994 Mar 1
44 8024602 Increased plasma and lipoprotein lipid peroxidation in apo E-deficient mice. Biochem Biophys Res Commun 1994 Jun 30 3
45 8040345 Apolipoprotein AI transgene corrects apolipoprotein E deficiency-induced atherosclerosis in mice. J Clin Invest 1994 Aug 2
46 8127890 A plasma lipoprotein containing only apolipoprotein E and with gamma mobility on electrophoresis releases cholesterol from cells. Proc Natl Acad Sci U S A 1994 Mar 1 2
47 8163669 Overexpression of apolipoprotein CII causes hypertriglyceridemia in transgenic mice. J Clin Invest 1994 Apr 2
48 8182153 Secretion-recapture process of apolipoprotein E in hepatic uptake of chylomicron remnants in transgenic mice. J Clin Invest 1994 May 1
49 8183926 The two-receptor model of lipoprotein clearance: tests of the hypothesis in "knockout" mice lacking the low density lipoprotein receptor, apolipoprotein E, or both proteins. Proc Natl Acad Sci U S A 1994 May 10 2
50 8280184 Exogenous glucocorticoids increase macrophage secretion of apo E by cholesterol-independent pathways. Atherosclerosis 1993 Oct 18