SGT1 homolog, MIS12 kinetochore complex assembly cochaperone ; Homo sapiens






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1 12456004 Schizosaccharomyces pombe Git7p, a member of the Saccharomyces cerevisiae Sgtlp family, is required for glucose and cyclic AMP signaling, cell wall integrity, and septation. Eukaryot Cell 2002 Aug 2
2 14761955 Human Sgt1 binds HSP90 through the CHORD-Sgt1 domain and not the tetratricopeptide repeat domain. J Biol Chem 2004 Apr 16 1
3 15346769 Molecular cloning and characterization of SGT1.2, a novel splice variant of Homo sapiens SGT1. DNA Seq 2004 Apr 1
4 16501598 17-AAG, an Hsp90 inhibitor, causes kinetochore defects: a novel mechanism by which 17-AAG inhibits cell proliferation. Oncogene 2006 Jul 13 1
5 17466273 Hsp70 is a new target of Sgt1--an interaction modulated by S100A6. Biochem Biophys Res Commun 2007 Jun 15 2
6 18358234 Sgt1 has co-chaperone properties and is up-regulated by heat shock. Biochem Biophys Res Commun 2008 May 23 1
7 18833289 Structural and functional analysis of SGT1-HSP90 core complex required for innate immunity in plants. EMBO Rep 2008 Dec 1
8 20213445 S100A6 mediates nuclear translocation of Sgt1: a heat shock-regulated protein. Amino Acids 2011 Oct 2
9 20670895 Structural basis for assembly of Hsp90-Sgt1-CHORD protein complexes: implications for chaperoning of NLR innate immunity receptors. Mol Cell 2010 Jul 30 1
10 21897126 For security and stability: SGT1 in plant defense and development. Plant Signal Behav 2011 Oct 1
11 22869522 Plk1 phosphorylates Sgt1 at the kinetochores to promote timely kinetochore-microtubule attachment. Mol Cell Biol 2012 Oct 1
12 26540294 Metabolomic Quantitative Trait Loci (mQTL) Mapping Implicates the Ubiquitin Proteasome System in Cardiovascular Disease Pathogenesis. PLoS Genet 2015 Nov 1
13 28696259 Interplay between the phosphatase PHLPP1 and E3 ligase RNF41 stimulates proper kinetochore assembly via the outer-kinetochore protein SGT1. J Biol Chem 2017 Aug 25 4
14 29387685 The Stoichiometric Interaction of the Hsp90-Sgt1-Rar1 Complex by CD and SRCD Spectroscopy. Front Mol Biosci 2017 5
15 32514048 SUGT1 controls susceptibility to HIV-1 infection by stabilizing microtubule plus-ends. Cell Death Differ 2020 Dec 1
16 34827672 Sgt1 Regulates α-Synuclein Subcellular Localization and Expression of Parkinson's Disease Related Genes, <i>PINK1</i> and <i>PARK9</i>. Biomolecules 2021 Nov 11 1
17 35131438 Polycistronic baculovirus expression of SUGT1 enables high-yield production of recombinant leucine-rich repeat proteins and protein complexes. Protein Expr Purif 2022 May 2