NLR family member X1 ; Mus musculus






20 Article(s)
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1 24867956 The mitochondrial protein NLRX1 controls the balance between extrinsic and intrinsic apoptosis. J Biol Chem 2014 Jul 11 5
2 25540124 Nlrx1 regulates neuronal cell death. Mol Brain 2014 Dec 24 1
3 25639646 NLRX1 acts as tumor suppressor by regulating TNF-α induced apoptosis and metabolism in cancer cells. Biochim Biophys Acta 2015 May 2
4 25938787 Suppression of NLRX1 in chronic obstructive pulmonary disease. J Clin Invest 2015 Jun 1
5 26836140 The expression of NLRX1 in C57BL/6 mice cochlear hair cells: Possible relation to aging- and neomycin-induced deafness. Neurosci Lett 2016 Mar 11 5
6 26971996 NLRX1 Acts as an Epithelial-Intrinsic Tumor Suppressor through the Modulation of TNF-Mediated Proliferation. Cell Rep 2016 Mar 22 1
7 27078069 NLRX1 Sequesters STING to Negatively Regulate the Interferon Response, Thereby Facilitating the Replication of HIV-1 and DNA Viruses. Cell Host Microbe 2016 Apr 13 1
8 27105514 NLRX1 suppresses tumorigenesis and attenuates histiocytic sarcoma through the negative regulation of NF-κB signaling. Oncotarget 2016 May 31 1
9 28159898 NLRX1 Regulates Effector and Metabolic Functions of CD4<sup>+</sup> T Cells. J Immunol 2017 Mar 15 1
10 29514047 Deletion of NLRX1 increases fatty acid metabolism and prevents diet-induced hepatic steatosis and metabolic syndrome. Biochim Biophys Acta Mol Basis Dis 2018 May 4
11 29577109 Male Mice Lacking NLRX1 Are Partially Protected From High-Fat Diet-Induced Hyperglycemia. J Endocr Soc 2018 Apr 1 4
12 30559741 NLRX1 Facilitates <i>Histoplasma capsulatum</i>-Induced LC3-Associated Phagocytosis for Cytokine Production in Macrophages. Front Immunol 2018 2
13 31052241 NLRX1 Enhances Glutamate Uptake and Inhibits Glutamate Release by Astrocytes. Cells 2019 Apr 30 6
14 31525189 NLRX1 inhibits the early stages of CNS inflammation and prevents the onset of spontaneous autoimmunity. PLoS Biol 2019 Sep 1
15 31681307 NLRX1 Is a Multifaceted and Enigmatic Regulator of Immune System Function. Front Immunol 2019 1
16 31694910 Activation of NLRX1 by NX-13 Alleviates Inflammatory Bowel Disease through Immunometabolic Mechanisms in CD4<sup>+</sup> T Cells. J Immunol 2019 Dec 15 1
17 32194859 LRR domain of NLRX1 protein delivery by dNP2 inhibits T cell functions and alleviates autoimmune encephalomyelitis. Theranostics 2020 1
18 33362773 NLRX1 Deletion Increases Ischemia-Reperfusion Damage and Activates Glucose Metabolism in Mouse Heart. Front Immunol 2020 4
19 34087956 Nucleotide-binding domain and leucine-rich-repeat-containing protein X1 deficiency induces nicotinamide adenine dinucleotide decline, mechanistic target of rapamycin activation, and cellular senescence and accelerates aging lung-like changes. Aging Cell 2021 Jul 7
20 35414088 Morphine-induced microglial immunosuppression via activation of insufficient mitophagy regulated by NLRX1. J Neuroinflammation 2022 Apr 12 7