interleukin 10 receptor subunit alpha ; Homo sapiens






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1 8120391 Expression cloning and characterization of a human IL-10 receptor. J Immunol 1994 Feb 15 1
2 8992974 The EBV IL-10 homologue is a selective agonist with impaired binding to the IL-10 receptor. J Immunol 1997 Jan 15 1
3 9117516 1,25-(OH)2-vitamin D3 and calcipotriol induce IL-10 receptor gene expression in human epidermal cells. Inflamm Res 1997 Jan 8
4 9463379 IL-10 inhibits macrophage activation and proliferation by distinct signaling mechanisms: evidence for Stat3-dependent and -independent pathways. EMBO J 1998 Feb 16 1
5 10231374 Purification of receptor complexes of interleukin-10 stoichiometry and the importance of deglycosylation in their crystallization. Eur J Biochem 1999 May 1
6 10433356 The interleukin-10 signal transduction pathway and regulation of gene expression in mononuclear phagocytes. J Interferon Cytokine Res 1999 Jun 1
7 10563471 Differential IL-10 receptor gene expression in acute versus chronic atopic eczema. Modulation by immunosuppressive drugs and cytokines in normal cultured keratinocytes. Inflamm Res 1999 Oct 2
8 11739506 Differential IL-10R1 expression plays a critical role in IL-10-mediated immune regulation. J Immunol 2001 Dec 15 2
9 11895951 Autocrine and exocrine regulation of interleukin-10 production in THP-1 cells stimulated with Borrelia burgdorferi lipoproteins. Infect Immun 2002 Apr 2
10 12093920 Crystal structure of human cytomegalovirus IL-10 bound to soluble human IL-10R1. Proc Natl Acad Sci U S A 2002 Jul 9 1
11 12121653 Noncompetitive antibody neutralization of IL-10 revealed by protein engineering and x-ray crystallography. Structure 2002 Jul 3
12 12356680 Molecular basis of the synergistic production of IL-1 receptor antagonist by human neutrophils stimulated with IL-4 and IL-10. Int Immunol 2002 Oct 1
13 12802285 IL-10 signaling via IL-10E1 is dependent on tyrosine phosphorylation in the IL-10R alpha chain in human primary prostate cancer cell lines. Oncogene 2003 Jun 12 8
14 16982608 Conformational changes mediate interleukin-10 receptor 2 (IL-10R2) binding to IL-10 and assembly of the signaling complex. J Biol Chem 2006 Nov 17 2
15 17056528 IL-10 signaling is essential for 1,25-dihydroxyvitamin D3-mediated inhibition of experimental autoimmune encephalomyelitis. J Immunol 2006 Nov 1 1
16 17121792 The cytomegalovirus homolog of interleukin-10 requires phosphatidylinositol 3-kinase activity for inhibition of cytokine synthesis in monocytes. J Virol 2007 Feb 1
17 19016528 Differential signaling of cmvIL-10 through common variants of the IL-10 receptor 1. Eur J Immunol 2008 Dec 7
18 20462497 Structure and mechanism of receptor sharing by the IL-10R2 common chain. Structure 2010 May 12 1
19 21592111 Blocking the immunosuppressive axis with small interfering RNA targeting interleukin (IL)-10 receptor enhances dendritic cell-based vaccine potency. Clin Exp Immunol 2011 Aug 2
20 22549091 Loss of interleukin-10 signaling and infantile inflammatory bowel disease: implications for diagnosis and therapy. Gastroenterology 2012 Aug 2
21 22692218 Epstein-Barr virus IL-10 engages IL-10R1 by a two-step mechanism leading to altered signaling properties. J Biol Chem 2012 Aug 3 2
22 23064239 Graphene oxide absorbed anti-IL10R antibodies enhance LPS induced immune responses in vitro and in vivo. Immunol Lett 2012 Dec 17 1
23 23554682 mRNA profiles of cytokine receptors in unstimulated peripheral blood mononuclear cells from patients with chronic idiopathic urticaria. J Biomed Res 2011 Mar 3
24 24398031 IL28B and IL10R -1087 polymorphisms are protective for chronic genotype 1 HCV infection and predictors of response to interferon-based therapy in an East-Central European cohort. BMC Res Notes 2014 Jan 8 1
25 25074615 Harnessing the intestinal microbiome for optimal therapeutic immunomodulation. Cancer Res 2014 Aug 15 1
26 26023679 Human Cytomegalovirus interleukin-10 promotes proliferation and migration of MCF-7 breast cancer cells. Cancer Cell Microenviron 2015 1
27 26792743 Human Cytomegalovirus-Encoded Human Interleukin-10 (IL-10) Homolog Amplifies Its Immunomodulatory Potential by Upregulating Human IL-10 in Monocytes. J Virol 2016 Apr 2
28 26962683 IL10 inhibits starvation-induced autophagy in hypertrophic scar fibroblasts via cross talk between the IL10-IL10R-STAT3 and IL10-AKT-mTOR pathways. Cell Death Dis 2016 Mar 10 3
29 28293795 A workflow for in silico design of hIL-10 and ebvIL-10 inhibitors using well-known miniprotein scaffolds. J Mol Model 2017 Apr 4
30 28893958 Microbial-Derived Butyrate Promotes Epithelial Barrier Function through IL-10 Receptor-Dependent Repression of Claudin-2. J Immunol 2017 Oct 15 4
31 29190740 Correlation of serum cytokines, chemokines, growth factors and enzymes with periodontal disease parameters. PLoS One 2017 1
32 30964577 Human cytomegalovirus IL-10 augments NK cell cytotoxicity. J Leukoc Biol 2019 Aug 1
33 30975555 Postprandial inflammatory responses after oral glucose, lipid and protein challenges: Influence of obesity, sex and polycystic ovary syndrome. Clin Nutr 2020 Mar 1
34 31342610 The effects of Cernitin® on inflammatory parameters and benign prostatic hyperplasia: An in vitro study. Phytother Res 2019 Sep 1
35 31889944 Neonatal Crohn's disease with Oral ulcer as the first symptom caused by a compound heterozygote mutation in IL-10RA: a case report. Hereditas 2019 2
36 32240179 Interleukin-10 contributes to PGE2 signalling through upregulation of EP4 via SHIP1 and STAT3. PLoS One 2020 3
37 32276346 Regulatory T Cells Modulate CD4 Proliferation after Severe Trauma via IL-10. J Clin Med 2020 Apr 8 1
38 32573700 IL10RA modulates crizotinib sensitivity in NPM1-ALK+ anaplastic large cell lymphoma. Blood 2020 Oct 1 3
39 32682256 ACTH<sub>4-10</sub> protects the ADR-injured podocytes by stimulating B lymphocytes to secrete interleukin-10. Int Immunopharmacol 2020 Oct 1
40 32838946 Identification of a novel signaling complex containing host chemokine receptor CXCR4, Interleukin-10 receptor, and human cytomegalovirus US27. Virology 2020 Sep 1
41 34536483 Tofacitinib Suppresses IL-10/IL-10R Signaling and Modulates Host Defense Responses in Human Macrophages. J Invest Dermatol 2022 Mar 3