hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 ; Homo sapiens






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1 36690 Steroid specificity of human placental 5-ene-3 beta-hydroxysteroid oxidoreductase. Steroids 1979 Jan 5
2 264670 Relationship between the soluble glutathione-dependent delta 5-3-ketosteroid isomerase and the glutathione S-transferases of the liver. Proc Natl Acad Sci U S A 1977 Jan 2
3 305825 Electron microscopic localization of 3beta-hydroxysteroid dehydrogenase and NADH-ferricyanide reductase activities in amphibian interrenal cells. Cell Tissue Res 1978 Mar 31 1
4 559585 Pregnant mare serum and human chorionic gonadotropin stimulate ovarian delta5-3beta-hydroxysteroid dehydrogenase in aged mice. Fertil Steril 1977 Jul 1
5 743993 Steroidogenesis in rat Leydig cells: effect of gonadotropins on the activity of 5-ane and 5-ene 3alpha- and 3beta-hydroxysteroid dehydrogenases during sexual maturation. Endocrinology 1978 Mar 1
6 893400 A novel chemical modification of delta 5-3-ketosteroid isomerase occurring during its 3-oxo-4-estren-17 beta-yl acetate-dependent photoinactivation. J Biol Chem 1977 Sep 10 2
7 909439 Labeling of delta5-3-ketosteroid isomerase by photoexcited steroid ketones. Methods Enzymol 1977 1
8 940160 Characterization of hexagonal crystal form of an enzyme of steroid metabolism, delta5-3-ketosteroid isomerase: a new method of crystal density measurement. J Mol Biol 1976 May 25 1
9 1325152 Expression of 17 alpha-hydroxylase and 3 beta-hydroxysteroid dehydrogenase in fetal human adrenocortical cells transfected with SV40 T antigen. J Mol Endocrinol 1992 Aug 3
10 1381375 Immunohistochemical localization of 3 beta-hydroxy-5-ene-steroid dehydrogenase/delta 5----delta 4 isomerase in human placenta and fetal membranes throughout gestation. J Clin Endocrinol Metab 1992 Sep 3
11 1390295 Ontogeny and subcellular localization of 3 beta-hydroxysteroid dehydrogenase (3 beta-HSD) in the human and rat adrenal, ovary and testis. J Steroid Biochem Mol Biol 1992 Oct 3
12 1401999 Characterization, expression, and immunohistochemical localization of 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4 isomerase in human skin. J Invest Dermatol 1992 Oct 3
13 1425410 Role of luteinizing hormone in the expression of cholesterol side-chain cleavage cytochrome P450 and 3 beta-hydroxysteroid dehydrogenase, delta 5-4 isomerase messenger ribonucleic acids in the primate corpus luteum. Endocrinology 1992 Nov 1
14 1525044 Influence of 19-nortestosterone and androgens on progesterone biosynthetic enzymes in early human placental explants. J Steroid Biochem Mol Biol 1992 Sep 5
15 1562516 Structure and tissue-specific expression of 3 beta-hydroxysteroid dehydrogenase/5-ene-4-ene isomerase genes in human and rat classical and peripheral steroidogenic tissues. J Steroid Biochem Mol Biol 1992 Mar 4
16 1569177 Immunocytochemical localization of 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4-isomerase in human ovary. J Clin Endocrinol Metab 1992 May 3
17 1582424 Steroid hormone synthesis by a vaccinia enzyme: a new type of virus virulence factor. EMBO J 1992 May 3
18 1655393 Regulation of adrenal 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4-isomerase expression and activity by adrenocorticotropin and corticosterone in the rat. Endocrinology 1991 Oct 1
19 1700972 Immunohistochemical study of 3 beta-hydroxysteroid dehydrogenase in sex cord-stromal tumors of the ovary. Int J Gynecol Pathol 1990 4
20 1831194 Characterization of the structure-activity relationships of rat types I and II 3 beta-hydroxysteroid dehydrogenase/delta 5 -delta 4 isomerase by site-directed mutagenesis and expression in HeLa cells. J Biol Chem 1991 Aug 15 9
21 1834689 3 beta-Hydroxysteroid dehydrogenase activity in glandular and extraglandular human fetal tissues. J Clin Endocrinol Metab 1991 Nov 5
22 1846095 Regulation of 3 beta-hydroxysteroid dehydrogenase/delta 5----4-isomerase expression by adrenocorticotropin in bovine adrenocortical cells. Endocrinology 1991 Jan 5
23 1848566 Low expression of 3 beta-hydroxy-5-ene steroid dehydrogenase gene in human fetal adrenals in vivo; adrenocorticotropin and protein kinase C-dependent regulation in adrenocortical cultures. J Clin Endocrinol Metab 1991 Apr 3
24 1851115 Corticotropin regulation of 3 beta-hydroxysteroid dehydrogenase/delta 5----4-isomerase in ovine adrenocortical cells: inhibition by transforming growth factor beta. Mol Cell Endocrinol 1991 Mar 2
25 1911436 Analysis of coenzyme binding by human placental 3 beta-hydroxy-5-ene-steroid dehydrogenase and steroid 5----4-ene-isomerase using 5'-[p-(fluorosulfonyl)benzoyl]adenosine, an affinity labeling cofactor analog. J Steroid Biochem Mol Biol 1991 Oct 1
26 1917679 Ontogeny of 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4 isomerase (3 beta-HSD) in human testis as studied by immunocytochemistry. J Androl 1991 May-Jun 1
27 1944309 Structure and expression of a new complementary DNA encoding the almost exclusive 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4-isomerase in human adrenals and gonads. Mol Endocrinol 1991 Aug 12
28 1954880 Insulin mediators are the signal transduction system responsible for insulin's actions on human placental steroidogenesis. Endocrinology 1991 Dec 2
29 2050270 Characterization of macaque 3 beta-hydroxy-5-ene steroid dehydrogenase/delta 5-delta 4 isomerase: structure and expression in steroidogenic and peripheral tissues in primate. Mol Cell Endocrinol 1991 Feb 3
30 2143469 Effects of DHA-S on placental 3 beta-hydroxysteroid dehydrogenase activity, progesterone and 20 alpha-dihydroprogesterone concentrations in placenta and serum. Endocrinol Jpn 1990 Feb 6
31 2153675 Relationship between the newly identified bile acid binder and bile acid oxidoreductases in human liver. J Biol Chem 1990 Feb 5 1
32 2158427 3 beta-hydroxysteroid dehydrogenase/isomerase in the fetal zone and neocortex of the human fetal adrenal gland. Endocrinology 1990 May 2
33 2178218 Regulation of mRNA expression of 3 beta-hydroxy-5-ene steroid dehydrogenase in porcine granulosa cells in culture: a role for the protein kinase-C pathway. Mol Endocrinol 1990 Oct 5
34 2223781 Studies of the mechanism of the delta 5-3-ketosteroid isomerase reaction by substrate, solvent, and combined kinetic deuterium isotope effects on wild-type and mutant enzymes. Biochemistry 1990 Aug 14 1
35 2226300 Insulin-like growth factor II is a potent inhibitor of the aromatase activity of human placental cytotrophoblasts. Endocrinology 1990 Nov 4
36 2243100 Characterization of human 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4-isomerase gene and its expression in mammalian cells. J Biol Chem 1990 Nov 25 5
37 2268554 Inhibitory effect of synthetic progestins, 4-MA and cyanoketone on human placental 3 beta-hydroxysteroid dehydrogenase/5----4-ene-isomerase activity. J Steroid Biochem Mol Biol 1990 Oct 7
38 2351102 Light microscopic immunocytochemical localization of 3 beta-hydroxy-5-ene-steroid dehydrogenase/delta 5-delta 4-isomerase in the gonads and adrenal glands of the guinea pig. Endocrinology 1990 Jun 3
39 2370296 Proliferating human granulosa-lutein cells in long term monolayer culture: expression of aromatase, cholesterol side-chain cleavage, and 3 beta-hydroxysteroid dehydrogenase. J Clin Endocrinol Metab 1990 Jul 1
40 2551637 Insulin and insulin-like growth factor-I stimulate the 3 beta-hydroxysteroid dehydrogenase activity of human placental cytotrophoblasts. Endocrinology 1989 Oct 2
41 2630193 Assignment of the human 3 beta-hydroxysteroid dehydrogenase gene (HSDB3) to the p13 band of chromosome 1. Cytogenet Cell Genet 1989 3
42 2779238 Kinetic analysis of human placental, ovarian, and adrenal 3 beta-hydroxysteroid dehydrogenase inhibition by epostane in vitro. J Steroid Biochem 1989 Sep 2
43 2811376 Micromethod for the determination of 3-beta-HSD activity in cultured cells. J Steroid Biochem 1989 Oct 1
44 3025517 ACTH and thyroid hormone regulation of 3 beta-hydroxysteroid dehydrogenase activity in human fetal adrenocortical cells. J Steroid Biochem 1986 Dec 1
45 3107552 The inhibition of 3 beta HSD activity in porcine granulosa cells by 4-MA, a potent 5 alpha-reductase inhibitor. Biochem Biophys Res Commun 1987 Apr 14 2
46 3165109 delta 5-3 beta-hydroxysteroid dehydrogenase activity in sebaceous glands of scalp in male-pattern baldness. J Invest Dermatol 1988 Aug 7
47 3257193 Ketoconazole inhibits multiple steroidogenic enzymes involved in androgen biosynthesis in the human ovary. Fertil Steril 1988 Jan 3
48 3455692 Steroid inhibitory effects upon human adrenal 3 beta-hydroxysteroid dehydrogenase activity. J Clin Endocrinol Metab 1986 Feb 10
49 3466494 Steroid spectrum in human urine as revealed by gas chromatography. VI. Pregnanediol excretion values and 3 beta-hydroxy-delta 5-steroid dehydrogenase activity of girls at different stage of development. Acta Biochim Biophys Hung 1986 5
50 3475511 Thecal cell 3-beta hydroxysteroid dehydrogenase activity: modulation by human chorionic gonadotropin, progesterone, estradiol-17 beta and dihydrotestosterone. J Steroid Biochem 1987 Jul 1