1 | 15138608 | Identification and characterization of JMJD2 family genes in silico. | Int J Oncol | 2004 Jun |
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2 | 16732293 | The putative oncogene GASC1 demethylates tri- and dimethylated lysine 9 on histone H3. | Nature | 2006 Jul 20 |
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3 | 19732750 | Jmjd2c histone demethylase enhances the expression of Mdm2 oncogene. | Biochem Biophys Res Commun | 2009 Nov 13 |
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4 | 19784073 | Genomic amplification and oncogenic properties of the GASC1 histone demethylase gene in breast cancer. | Oncogene | 2009 Dec 17 |
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5 | 20684604 | Design, synthesis, enzyme-inhibitory activity, and effect on human cancer cells of a novel series of jumonji domain-containing protein 2 histone demethylase inhibitors. | J Med Chem | 2010 Aug 12 |
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6 | 21156283 | Cooperative epigenetic modulation by cancer amplicon genes. | Cancer Cell | 2010 Dec 14 |
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7 | 21575637 | Enzyme kinetic studies of histone demethylases KDM4C and KDM6A: towards understanding selectivity of inhibitors targeting oncogenic histone demethylases. | FEBS Lett | 2011 Jun 23 |
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8 | 21859682 | High-throughput TR-FRET assays for identifying inhibitors of LSD1 and JMJD2C histone lysine demethylases. | J Biomol Screen | 2012 Jan |
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9 | 22420752 | Studies of H3K4me3 demethylation by KDM5B/Jarid1B/PLU1 reveals strong substrate recognition in vitro and identifies 2,4-pyridine-dicarboxylic acid as an in vitro and in cell inhibitor. | FEBS J | 2012 Jun |
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10 | 22917519 | Inhibitor scaffold for the histone lysine demethylase KDM4C (JMJD2C). | Bioorg Med Chem Lett | 2012 Sep 15 |
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11 | 23129632 | Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression. | Proc Natl Acad Sci U S A | 2012 Dec 4 |
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12 | 23384557 | The lysine specific demethylase-1 (LSD1/KDM1A) regulates VEGF-A expression in prostate cancer. | Mol Oncol | 2013 Jun |
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13 | 23692052 | Structural investigations of the nickel-induced inhibition of truncated constructs of the JMJD2 family of histone demethylases using X-ray absorption spectroscopy. | Biochemistry | 2013 Jun 18 |
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14 | 23884959 | Hypoxia enhances the expression of prostate-specific antigen by modifying the quantity and catalytic activity of Jumonji C domain-containing histone demethylases. | Carcinogenesis | 2013 Dec |
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15 | 24371038 | GASC1 expression in lung carcinoma is associated with smoking and prognosis of squamous cell carcinoma. | Histol Histopathol | 2014 Jun |
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16 | 24394434 | Phospho-ΔNp63α/microRNA network modulates epigenetic regulatory enzymes in squamous cell carcinomas. | Cell Cycle | 2014 |
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17 | 24936217 | Pro-growth role of the JMJD2C histone demethylase in HCT-116 colon cancer cells and identification of curcuminoids as JMJD2 inhibitors. | Am J Transl Res | 2014 |
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18 | 24952432 | A polymorphism in JMJD2C alters the cleavage by caspase-3 and the prognosis of human breast cancer. | Oncotarget | 2014 Jul 15 |
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19 | 25014588 | Substrate- and cofactor-independent inhibition of histone demethylase KDM4C. | ACS Chem Biol | 2014 Sep 19 |
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20 | 26747609 | Opposing Chromatin Signals Direct and Regulate the Activity of Lysine Demethylase 4C (KDM4C). | J Biol Chem | 2016 Mar 18 |
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21 | 26774480 | KDM4C and ATF4 Cooperate in Transcriptional Control of Amino Acid Metabolism. | Cell Rep | 2016 Jan 26 |
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22 | 27295953 | Synthesis and Characterisation of Substrate-Based Peptides as Inhibitors of Histone Demethylase KDM4C. | Protein Pept Lett | 2016 |
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23 | 27742014 | KDM4C, a H3K9me3 Histone Demethylase, is Involved in the Maintenance of Human ESCC-Initiating Cells by Epigenetically Enhancing SOX2 Expression. | Neoplasia | 2016 Oct |
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24 | 28236704 | Jumonji domain containing 2C promotes cell migration and invasion through modulating CUL4A expression in lung cancer. | Biomed Pharmacother | 2017 May |
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25 | 28396876 | Reduced Histone H3 Lysine 9 Methylation Contributes to the Pathogenesis of Latent Autoimmune Diabetes in Adults via Regulation of SUV39H2 and KDM4C. | J Diabetes Res | 2017 |
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26 | 29207681 | Histone demethylase JMJD2C: epigenetic regulators in tumors. | Oncotarget | 2017 Oct 31 |
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27 | 29718303 | The KDM4A/KDM4C/NF-κB and WDR5 epigenetic cascade regulates the activation of B cells. | Nucleic Acids Res | 2018 Jun 20 |
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28 | 30132131 | Genetic alterations of 9p24 in lymphomas and their impact for cancer (immuno-)therapy. | Virchows Arch | 2019 Apr |
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29 | 30537731 | circZMYM2 Competed Endogenously with miR-335-5p to Regulate JMJD2C in Pancreatic Cancer. | Cell Physiol Biochem | 2018 |
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30 | 30640062 | Sufficiency of hypoxia-inducible 2-oxoglutarate dioxygenases to block chemical oxidative stress-induced differentiation of human embryonic stem cells. | Stem Cell Res | 2019 Jan |
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31 | 31270335 | Iron-dependent histone 3 lysine 9 demethylation controls B cell proliferation and humoral immune responses. | Nat Commun | 2019 Jul 3 |
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32 | 31665047 | JMJD2C promotes colorectal cancer metastasis via regulating histone methylation of MALAT1 promoter and enhancing β-catenin signaling pathway. | J Exp Clin Cancer Res | 2019 Oct 29 |
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33 | 31766290 | Histone Demethylase KDM4C Stimulates the Proliferation of Prostate Cancer Cells via Activation of AKT and c-Myc. | Cancers (Basel) | 2019 Nov 13 |
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34 | 31784197 | Rational design, synthesis and biological profiling of new KDM4C inhibitors. | Bioorg Med Chem | 2020 Jan 1 |
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35 | 32972441 | microRNA-216b enhances cisplatin-induced apoptosis in osteosarcoma MG63 and SaOS-2 cells by binding to JMJD2C and regulating the HIF1α/HES1 signaling axis. | J Exp Clin Cancer Res | 2020 Sep 24 |
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36 | 33413524 | Correction to: microRNA-216b enhances cisplatin-induced apoptosis in osteosarcoma MG63 and SaOS-2 cells by binding to JMJD2C and regulating the HIF1α/HES1 signaling axis. | J Exp Clin Cancer Res | 2021 Jan 7 |
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37 | 33649841 | GASC1 promotes glioma progression by enhancing NOTCH1 signaling. | Mol Med Rep | 2021 May |
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38 | 35414503 | Histone Demethylase GASC1 Inhibitor Targeted GASC1 Gene to Inhibit the Malignant Transformation of Esophageal Cancer through the NOTCH-MAPK Signaling Pathway. | Ann Clin Lab Sci | 2022 Mar |
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39 | 35468881 | JMJD2C mediates the MDM2/p53/IL5RA axis to promote CDDP resistance in uveal melanoma. | Cell Death Discov | 2022 Apr 25 |
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