apelin receptor ; Rattus norvegicus






41 Article(s)
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1 9565257 Gut endotoxin restriction improves postoperative hemodynamics in the bile duct-ligated rat. Shock 1998 Apr 1
2 11883945 The effects of centrally administered apelin-13 on food intake, water intake and pituitary hormone release in rats. Biochem Biophys Res Commun 2002 Mar 15 1
3 15664402 Effects of all-trans retinoic acid on orphan receptor APJ signaling in spontaneously hypertensive rats. Cardiovasc Res 2005 Feb 15 3
4 17612598 Effect of nitric oxide on the expression of apelin receptor mRNA in rat caudate nucleus. Neurosci Bull 2007 May 5
5 19346461 Apelin decreases myocardial injury and improves right ventricular function in monocrotaline-induced pulmonary hypertension. Am J Physiol Heart Circ Physiol 2009 Jun 2
6 19904215 Effects of olmesartan on Apelin/APJ and Akt/endothelial nitric oxide synthase pathway in Dahl rats with end-stage heart failure. J Cardiovasc Pharmacol 2010 Jan 3
7 20353015 [Effects of puerarin on expression of apelin and its receptor of 2K1C renal hypertension rats]. Zhongguo Zhong Yao Za Zhi 2009 Dec 1
8 22160265 Prevention of fibrosis progression in CCl4-treated rats: role of the hepatic endocannabinoid and apelin systems. J Pharmacol Exp Ther 2012 Mar 1
9 23668014 [Effect of puerarin combined with felodipine on mRNA and protein expression of apelin and APJ in renovascular hypertensive rat]. Zhongguo Zhong Yao Za Zhi 2013 Feb 7
10 23833956 [Changes of apelin and its receptor in lung tissue of rats with pulmonary hypertension induced by monocrotaline]. Zhongguo Ying Yong Sheng Li Xue Za Zhi 2013 Mar 1
11 24363088 Decreased apelin and apelin-receptor expression in the pulmonary vasculature of nitrofen-induced congenital diaphragmatic hernia. Pediatr Surg Int 2014 Feb 4
12 24411164 The effects of water immersion and restraint stress on the expressions of apelin, apelin receptor (APJR) and apoptosis rate in the rat heart. Acta Histochem 2014 Jun 1
13 24447518 Apelin inhibits the proliferation and migration of rat PASMCs via the activation of PI3K/Akt/mTOR signal and the inhibition of autophagy under hypoxia. J Cell Mol Med 2014 Mar 1
14 24770651 Regulation of apelin and its receptor expression in adipose tissues of obesity rats with hypertension and cultured 3T3-L1 adipocytes. Exp Anim 2014 2
15 24966188 A static pressure sensitive receptor APJ promote H9c2 cardiomyocyte hypertrophy via PI3K-autophagy pathway. Acta Biochim Biophys Sin (Shanghai) 2014 Aug 2
16 24993609 Effect of apelin on the cardiac hemodynamics in hypertensive rats with heart failure. Int J Mol Med 2014 Sep 2
17 24995933 Apelin-13 and APJ in paraventricular nucleus contribute to hypertension via sympathetic activation and vasopressin release in spontaneously hypertensive rats. Acta Physiol (Oxf) 2014 Sep 1
18 25375801 The Apelin-APJ axis is an endogenous counterinjury mechanism in experimental acute lung injury. Chest 2015 Apr 3
19 25681427 Possible involvement of downregulation of the apelin-APJ system in doxorubicin-induced cardiotoxicity. Am J Physiol Heart Circ Physiol 2015 Apr 15 1
20 27328502 Effects of apelin on proliferation and apoptosis in rat ovarian granulosa cells. Clin Exp Obstet Gynecol 2016 2
21 27664950 Anticonvulsant and neuroprotective effects of apelin-13 on pentylenetetrazole-induced seizures in male rats. Biomed Pharmacother 2016 Dec 1
22 28065733 Amelioration of apelin-13 in chronic normobaric hypoxia-induced anxiety-like behavior is associated with an inhibition of NF-κB in the hippocampus. Brain Res Bull 2017 Apr 2
23 28144460 The Effect of Aerobic Exercise Training on Plasma Apelin Levels and Pain Threshold in T1DM Rats. Iran Red Crescent Med J 2016 Sep 1
24 28627589 Effect of the spinal apelin‑APJ system on the pathogenesis of chronic constriction injury‑induced neuropathic pain in rats. Mol Med Rep 2017 Aug 4
25 28962638 Hypoxia preconditioning promotes cardiac stem cell survival and cardiogenic differentiation in vitro involving activation of the HIF-1α/apelin/APJ axis. Stem Cell Res Ther 2017 Sep 29 1
26 30582943 Superoxide anions modulate the performance of apelin in the paraventricular nucleus on sympathetic activity and blood pressure in spontaneously hypertensive rats. Peptides 2019 Nov 2
27 30710493 A novel cyclic biased agonist of the apelin receptor, MM07, is disease modifying in the rat monocrotaline model of pulmonary arterial hypertension. Br J Pharmacol 2019 May 1
28 30942406 (3R)‑5,6,7‑trihydroxy‑3‑isopropyl‑3‑methylisochroman‑1‑one attenuates cardiac dysfunction via the apelin/APJ signaling pathway. Mol Med Rep 2019 Jun 1
29 31040784 Apelin-13 Suppresses Neuroinflammation Against Cognitive Deficit in a Streptozotocin-Induced Rat Model of Alzheimer's Disease Through Activation of BDNF-TrkB Signaling Pathway. Front Pharmacol 2019 1
30 31657686 Targeting Hypertension: Superoxide Anions are Involved in Apelininduced Long-term High Blood Pressure and Sympathetic Activity in the Paraventricular Nucleus. Curr Neurovasc Res 2019 1
31 31834836 Exacerbated pressor and sympathoexcitatory effects of central Elabela in spontaneously hypertensive rats. Am J Physiol Heart Circ Physiol 2020 Jan 1 1
32 32580404 Flutamide Alters the Expression of Chemerin, Apelin, and Vaspin and Their Respective Receptors in the Testes of Adult Rats. Int J Mol Sci 2020 Jun 22 1
33 32585603 The effect of olmesartan on aortic intimal thickening after balloon injury through Apelin/APJ. Cardiovasc Pathol 2020 Nov - Dec 3
34 32858124 Half-life extension of peptidic APJ agonists by N-terminal lipid conjugation. Bioorg Med Chem Lett 2020 Nov 1 3
35 33278072 L-carnitine improves metabolic disorders and regulates apelin and apelin receptor genes expression in adipose tissue in diabetic rats. Physiol Rep 2020 Dec 3
36 33436646 A metabolically stable apelin-17 analog decreases AVP-induced antidiuresis and improves hyponatremia. Nat Commun 2021 Jan 12 2
37 33524256 Constraining the Side Chain of C-Terminal Amino Acids in Apelin-13 Greatly Increases Affinity, Modulates Signaling, and Improves the Pharmacokinetic Profile. J Med Chem 2021 May 13 1
38 33635165 Gαi-biased apelin analog protects against isoproterenol-induced myocardial dysfunction in rats. Am J Physiol Heart Circ Physiol 2021 Apr 1 6
39 34385922 Elabela Protects Spontaneously Hypertensive Rats From Hypertension and Cardiorenal Dysfunctions Exacerbated by Dietary High-Salt Intake. Front Pharmacol 2021 1
40 34393794 LIT01-196, a Metabolically Stable Apelin-17 Analog, Normalizes Blood Pressure in Hypertensive DOCA-Salt Rats <i>via</i> a NO Synthase-dependent Mechanism. Front Pharmacol 2021 1
41 35000047 Apelin-13 attenuates early brain injury through inhibiting inflammation and apoptosis in rats after experimental subarachnoid hemorrhage. Mol Biol Rep 2022 Mar 1