solute carrier family 31 member 1 ; Homo sapiens






323 Article(s)
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1 9207117 hCTR1: a human gene for copper uptake identified by complementation in yeast. Proc Natl Acad Sci U S A 1997 Jul 8 4
2 9928480 The ethylene gas signal transduction pathway: a molecular perspective. Annu Rev Genet 1998 1
3 11054564 Characterization of the hCTR1 gene: genomic organization, functional expression, and identification of a highly homologous processed gene. Gene 2000 Oct 17 5
4 11391004 The copper transporter CTR1 provides an essential function in mammalian embryonic development. Proc Natl Acad Sci U S A 2001 Jun 5 5
5 11391005 Essential role for mammalian copper transporter Ctr1 in copper homeostasis and embryonic development. Proc Natl Acad Sci U S A 2001 Jun 5 3
6 11734551 Biochemical characterization of the human copper transporter Ctr1. J Biol Chem 2002 Feb 8 6
7 12023893 Biochemical characterization and subcellular localization of human copper transporter 1 (hCTR1). Biochem J 2002 Jun 1 5
8 12034741 Molecular characterization of hCTR1, the human copper uptake protein. J Biol Chem 2002 Aug 9 9
9 12078916 Understanding copper uptake at the molecular level. Nutr Rev 2002 Jun 1
10 12220667 Effects of copper on the expression of metal transporters in human intestinal Caco-2 cells. FEBS Lett 2002 Sep 11 1
11 12370430 Uptake of the anticancer drug cisplatin mediated by the copper transporter Ctr1 in yeast and mammals. Proc Natl Acad Sci U S A 2002 Oct 29 2
12 12466020 The N-terminus of the human copper transporter 1 (hCTR1) is localized extracellularly, and interacts with itself. Biochem J 2003 Mar 15 3
13 12501239 Copper-stimulated endocytosis and degradation of the human copper transporter, hCtr1. J Biol Chem 2003 Mar 14 6
14 12531240 Ctr1 and its role in body copper homeostasis. Int J Biochem Cell Biol 2003 Mar 5
15 12580789 Cloning, characterization and chromosomal localization of the Sus scrofa SLC31A1 gene. Anim Genet 2003 Feb 1
16 12872841 Mutation analysis of copper transporter genes in patients with ethylmalonic encephalopathy, mitochondriopathies and copper deficiency phenotypes. J Inherit Metab Dis 2003 4
17 12927968 Ethylene signaling: the MAPK module has finally landed. Trends Plant Sci 2003 Aug 2
18 14976198 Identification of methionine-rich clusters that regulate copper-stimulated endocytosis of the human Ctr1 copper transporter. J Biol Chem 2004 Apr 23 12
19 15023397 Functional and molecular responses of suckling rat pups and human intestinal Caco-2 cells to copper treatment. J Nutr Biochem 2004 Mar 8
20 15194000 Cellular pharmacology of cisplatin in relation to the expression of human copper transporter CTR1 in different pairs of cisplatin-sensitive and -resistant cells. Biochem Pharmacol 2004 Jul 15 7
21 15229296 The copper influx transporter human copper transport protein 1 regulates the uptake of cisplatin in human ovarian carcinoma cells. Mol Pharmacol 2004 Oct 17
22 15326162 Cisplatin stabilizes a multimeric complex of the human Ctr1 copper transporter: requirement for the extracellular methionine-rich clusters. J Biol Chem 2004 Nov 5 22
23 15475465 Cisplatin rapidly down-regulates its own influx transporter hCTR1 in cultured human ovarian carcinoma cells. Clin Cancer Res 2004 Oct 1 2
24 15591161 Effects of copper supplementation on copper absorption, tissue distribution, and copper transporter expression in an infant rat model. Am J Physiol Gastrointest Liver Physiol 2005 May 1
25 15607932 Copper transporters regulate the cellular pharmacology and sensitivity to Pt drugs. Crit Rev Oncol Hematol 2005 Jan 6
26 15634647 Role of human copper transporter Ctr1 in the transport of platinum-based antitumor agents in cisplatin-sensitive and cisplatin-resistant cells. Mol Cancer Ther 2004 Dec 19
27 15634665 Stable plasma membrane levels of hCTR1 mediate cellular copper uptake. J Biol Chem 2005 Mar 11 11
28 16135512 The mechanism of copper uptake mediated by human CTR1: a mutational analysis. J Biol Chem 2005 Nov 4 3
29 16356544 Expression, localisation and hormone regulation of the human copper transporter hCTR1 in placenta and choriocarcinoma Jeg-3 cells. Placenta 2006 Sep-Oct 3
30 16363848 A Mets motif peptide found in copper transport proteins selectively binds Cu(I) with methionine-only coordination. Inorg Chem 2005 Dec 26 3
31 16501047 Projection structure of the human copper transporter CTR1 at 6-A resolution reveals a compact trimer with a novel channel-like architecture. Proc Natl Acad Sci U S A 2006 Mar 7 2
32 16637264 [Relations between CTR1 gene activity and copper status in different rat organs]. Mol Biol (Mosk) 2006 Mar-Apr 7
33 16709730 Expression of the human copper influx transporter 1 in normal and malignant human tissues. J Histochem Cytochem 2006 Sep 2
34 16773204 Expression analysis of genes involved in oxaliplatin response and development of oxaliplatin-resistant HT29 colon cancer cells. Int J Oncol 2006 Jul 1
35 16982196 Structure of the Ctr1 copper trans'PORE'ter reveals novel architecture. Trends Biochem Sci 2006 Nov 1
36 17097621 Relevance of drug uptake and efflux for cisplatin sensitivity of tumor cells. Biochem Pharmacol 2007 Jan 15 4
37 17108132 The internalization and degradation of human copper transporter 1 following cisplatin exposure. Cancer Res 2006 Nov 15 14
38 17211679 Copper entry into human cells: progress and unanswered questions. Biometals 2007 Jun 2
39 17318448 The roles of copper transporters in cisplatin resistance. Cancer Metastasis Rev 2007 Mar 4
40 17525160 O-linked glycosylation at threonine 27 protects the copper transporter hCTR1 from proteolytic cleavage in mammalian cells. J Biol Chem 2007 Jul 13 9
41 17617060 Human copper transporter 2 is localized in late endosomes and lysosomes and facilitates cellular copper uptake. Biochem J 2007 Oct 1 2
42 17627945 Human copper transporter hCTR1 mediates basolateral uptake of copper into enterocytes: implications for copper homeostasis. J Biol Chem 2007 Sep 7 6
43 17695505 Effect of copper and role of the copper transporters ATP7A and CTR1 in intracellular accumulation of cisplatin. Anticancer Res 2007 Jul-Aug 3
44 17944601 Ctr2 is partially localized to the plasma membrane and stimulates copper uptake in COS-7 cells. Biochem J 2008 Feb 1 1
45 17959139 NMR and mutagenesis of human copper transporter 1 (hCtr1) show that Cys-189 is required for correct folding and dimerization. Biochim Biophys Acta 2007 Dec 4
46 18483225 Transcription factor Sp1 plays an important role in the regulation of copper homeostasis in mammalian cells. Mol Pharmacol 2008 Sep 15
47 18523133 Elevated glutathione levels confer cellular sensitization to cisplatin toxicity by up-regulation of copper transporter hCtr1. Mol Pharmacol 2008 Sep 5
48 18779302 Role of copper transporters in copper homeostasis. Am J Clin Nutr 2008 Sep 1
49 18779306 Intestinal regulation of copper homeostasis: a developmental perspective. Am J Clin Nutr 2008 Sep 3
50 18820153 Transporters in the absorption and utilization of zinc and copper. J Anim Sci 2009 Apr 2