asparaginase and isoaspartyl peptidase 1 ; Homo sapiens






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1 14784 Inhibitors of L-asparagine synthetase, in vitro. Cancer Treat Rep 1976 Oct 1
2 90334 Interaction of alpha 2-macroglobulin with L-asparaginase. Mol Cell Biochem 1979 Feb 9 4
3 287856 L-asparaginase used with cytosine arabinoside in treatment of childhood acute lymphocytic leukemia refractory to vincristine and prednisone. Med Pediatr Oncol 1979 3
4 294577 [Value of arginine-glucose preparation in the prevention of hyperammonemia in patients treated with L-asparaginase]. Pol Arch Med Wewn 1979 Dec 1
5 295575 L-asparaginase-induced hypocomplementemia in acute lymphocytic leukemia (ALL) of childhood. Am J Pediatr Hematol Oncol 1979 Spring 2
6 302863 L-asparagine requirements of human T-lymphocytes and B-lymphocytes in culture. J Natl Cancer Inst 1977 Oct 1
7 313838 Lessons from the study of induced alterations in amino acids in patients with cancer. Cancer Treat Rep 1979 Jun 1
8 363626 Mechanism of sensitivity of cultured pancreatic carcinoma to asparaginase. Int J Cancer 1978 Dec 2
9 596848 [Cellular test system for studying the biological properties of preparations with L-asparaginase activity]. Antibiotiki 1977 Nov 2
10 616416 Interaction of antitumor agents including doxorubicin or daunorubicin in sarcoma-180 system. Gan 1977 Aug 1
11 807012 Reduction of canine serum asparagine levels by L -asparaginase immobilized on collagen: a potential form of cancer chemotherapy. Trans Am Soc Artif Intern Organs 1975 1
12 849452 A spectrophotometric study of the reaction of boro-hydride with trinitrophenyl derivatives of amino acids and proteins. Biochim Biophys Acta 1977 Mar 28 1
13 909434 Active site of L-asparaginase: reaction with diazo-4-oxonorvaline. Methods Enzymol 1977 1
14 991148 Study of cytosine arabinoside (NSC-63878) synchronization plus vincristine (NSC-67574), prednisone (NSC-10023), and L-asparaginase (NSC-109229) for remission induction in advanced acute leukemia in children. Cancer Treat Rep 1976 May 1
15 1285501 The inhibition of lymphocyte blastogenesis by asparaginase: critical role of glutamine in both T and B lymphocyte transformation. Acta Paediatr Jpn 1992 Dec 1
16 1368489 Monoclonal antibodies can protect L-asparaginase against inactivation by trypsin. Biotechnology (N Y) 1992 Apr 1
17 1537631 Pre-treatment of a human T-lymphoblastoid cell line with L-asparaginase reduces etoposide-induced DNA strand breakage and cytotoxicity. Int J Cancer 1992 Feb 20 6
18 1551892 Substrate specificity and reaction mechanism of human glycoasparaginase. The N-glycosidic linkage of various glycoasparagines is cleaved through a reaction mechanism similar to L-asparaginase. J Biol Chem 1992 Apr 5 3
19 1567419 Chemical modification of L-asparaginase with a comb-shaped copolymer of polyethylene glycol derivative and maleic anhydride. Biochem Biophys Res Commun 1992 Apr 15 6
20 1602617 [Acute lymphocytic leukemia (L1) preceded by hypercalcemia]. Rinsho Ketsueki 1992 Apr 2
21 1712146 [Effect of several factors on enzymic activity and antigenicity in chemical modification of L-asparaginase]. Yao Xue Xue Bao 1990 3
22 1726615 Staphylococcal L-asparaginase: enzyme kinetics. Acta Microbiol Pol 1991 1
23 1731053 Differences in teniposide disposition and pharmacodynamics in patients with newly diagnosed and relapsed acute lymphocytic leukemia. J Pharmacol Exp Ther 1992 Jan 1
24 1742729 Measurement of serum L-asparagine in the presence of L-asparaginase requires the presence of an L-asparaginase inhibitor. Cancer Res 1991 Dec 15 43
25 1778615 Induction of L-asparaginase synthesis in Vibrio proteus. Indian J Med Res 1991 Sep 2
26 1861535 High efficacy of monomethoxypolyethylene glycol-conjugated L-asparaginase (PEG2-ASP) in two patients with hematological malignancies. Leuk Res 1991 3
27 2038322 A ras effector domain mutant which is temperature sensitive for cellular transformation: interactions with GTPase-activating protein and NF-1. Mol Cell Biol 1991 Jun 1
28 2041167 [L-asparaginase-induced hyperlipidemia in a case of acute lymphoblastic leukemia]. Rinsho Ketsueki 1991 Mar 3
29 2125695 Antiproliferative activity of L-asparaginase of Tetrahymena pyriformis on human breast cancer cell lines. Mol Cell Biochem 1990 Aug 10 3
30 2148229 L-asparaginase treatment reduces the anticoagulant potential of the protein C system without affecting vitamin K-dependent carboxylation. Thromb Res 1990 Sep 15 1
31 2242318 Leukaemia-associated hypercalcaemia in a 10-year-old boy: effectiveness of aminohydroxypropylidene biphosphonate. Pediatr Nephrol 1990 Sep 2
32 2333748 Electrolytes, amino acids and proteins in lumbar CSF during the treatment of acute leukemia in childhood. Acta Paediatr Scand 1990 Mar 2
33 2340464 High-dose cytosine arabinoside and L-asparaginase therapy for poor-risk adult acute nonlymphocytic leukemia. A retrospective study. Cancer 1990 Jun 15 1
34 2345067 A phase II trial of PEG-L-asparaginase in the treatment of non-Hodgkins lymphoma. Invest New Drugs 1990 Feb 1
35 2417103 [Polarization of intrinsic fluorescence of proteins. IV. Changes in the degree of polarization from the emission spectra]. Mol Biol (Mosk) 1985 Sep-Oct 1
36 2418896 The mutual relationship between the two molecular forms of the major fibrinolysis inhibitor alpha-2-antiplasmin in blood. Blood 1986 Mar 2
37 2564453 Biochemical characterization of U937 cells resistant to L-asparaginase: the role of asparagine synthetase. Leukemia 1989 Apr 1
38 2607611 [Study of reinduction chemotherapy in bone marrow relapse of childhood acute lymphoblastic leukemia]. Rinsho Ketsueki 1989 Nov 1
39 2665546 Effectiveness of rubidomycin in induction therapy with vincristine, prednisone, and L-asparaginase for standard risk childhood acute lymphocytic leukemia: results of a Dutch phase III study (ALL V). A report on behalf of the Dutch Childhood Leukemia Study Group (DCLSG). Am J Pediatr Hematol Oncol 1989 Summer 2
40 2671905 Direct long-term effects of L-asparaginase on rat and human pancreatic islets. Pediatr Res 1989 Aug 1
41 2743326 In vitro and in vivo killing of acute lymphoblastic leukemia cells by L-asparaginase. Cancer Res 1989 Aug 1 1
42 2872037 Clinical pharmacology of polyethylene glycol-L-asparaginase. Drug Metab Dispos 1986 May-Jun 2
43 2939229 Effect of L-asparaginase therapy for acute lymphoblastic leukemia on plasma vitamin K-dependent coagulation factors and inhibitors. J Pediatr 1986 May 2
44 3102431 Characterization of polyethylene glycol-modified L-asparaginase from Escherichia coli and its application to therapy of leukemia. Jpn J Cancer Res 1986 Dec 3
45 3210651 [Clinical experiences with polyethylene glycol-bound E. coli L-asparaginase in patients with multiple recurrences of acute lymphoblastic leukemia]. Klin Padiatr 1988 May-Jun 2
46 3415272 [VAMA salvage regimen (VP-16, ARA-C, MTX and L-asparaginase) in relapsed or resistant non-Hodgkin's lymphoma]. Gan To Kagaku Ryoho 1988 Sep 2
47 3422190 The effect of L-asparaginase on lipid metabolism during induction chemotherapy of childhood lymphoblastic leukaemia. Eur J Pediatr 1988 Jan 1
48 3444371 Increased membrane permeability for an antitumoral alkyl lysophospholipid in sensitive tumor cells. Lipids 1987 Nov 1
49 3475571 [Formation of specific IgG antibodies in l-asparaginase treatment. Distribution of IgG subclasses]. Monatsschr Kinderheilkd 1987 Jun 1
50 3585446 Evaluation of intensive postremission chemotherapy for adults with acute nonlymphocytic leukemia using high-dose cytosine arabinoside with L-asparaginase and amsacrine with etoposide. J Clin Oncol 1987 Jun 1