atlastin GTPase 1 ; Homo sapiens






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1 7825576 Autosomal dominant familial spastic paraplegia: reduction of the FSP1 candidate region on chromosome 14q to 7 cM and locus heterogeneity. Am J Hum Genet 1995 Jan 1
2 14506257 Cellular localization, oligomerization, and membrane association of the hereditary spastic paraplegia 3A (SPG3A) protein atlastin. J Biol Chem 2003 Dec 5 1
3 15901601 Novel lipid mediator aspirin-triggered lipoxin A4 induces heme oxygenase-1 in endothelial cells. Am J Physiol Cell Physiol 2005 Sep 2
4 16034127 Involvement of the Rho-kinase/myosin light chain kinase pathway on human monocyte chemotaxis induced by ATL-1, an aspirin-triggered lipoxin A4 synthetic analog. J Immunol 2005 Aug 1 7
5 16132039 Aspirin-triggered Lipoxin A4 inhibition of VEGF-induced endothelial cell migration involves actin polymerization and focal adhesion assembly. Oncogene 2006 Jan 5 3
6 16679453 A novel DNA damage recognition protein in Schizosaccharomyces pombe. Nucleic Acids Res 2006 5
7 17200775 Aspirin-triggered lipoxin A4 blocks reactive oxygen species generation in endothelial cells: a novel antioxidative mechanism. Thromb Haemost 2007 Jan 7
8 18193074 ATL-1, an analogue of aspirin-triggered lipoxin A4, is a potent inhibitor of several steps in angiogenesis induced by vascular endothelial growth factor. Br J Pharmacol 2008 Mar 6
9 19573020 Atlastin-1, the dynamin-like GTPase responsible for spastic paraplegia SPG3A, remodels lipid membranes and may form tubules and vesicles in the endoplasmic reticulum. J Neurochem 2009 Sep 2
10 20004734 A synthetic analog of 15-epi-lipoxin A4 inhibits human monocyte apoptosis: involvement of ERK-2 and PI3-kinase. Prostaglandins Other Lipid Mediat 2010 Feb 3
11 21597037 Glutamatergic signaling maintains the epithelial phenotype of proximal tubular cells. J Am Soc Nephrol 2011 Jun 1
12 23059787 Synthesis of oligodeoxyribonucleotides containing a conformationally-locked anti analogue of O6-methyl-2'-deoxyguanosine and their recognition by MGMT and Atl1. Chem Commun (Camb) 2012 Nov 25 3
13 23153508 Rac1/PAK1 signaling promotes epithelial-mesenchymal transition of podocytes in vitro via triggering β-catenin transcriptional activity under high glucose conditions. Int J Biochem Cell Biol 2013 Feb 2
14 23334294 Structural basis for conformational switching and GTP loading of the large G protein atlastin. EMBO J 2013 Feb 6 2
15 24172243 Anti-tumor effects of atractylenolide I isolated from Atractylodes macrocephala in human lung carcinoma cell lines. Molecules 2013 Oct 29 2
16 24887589 ATL-1, a synthetic analog of lipoxin, modulates endothelial permeability and interaction with tumor cells through a VEGF-dependent mechanism. Biochem Pharmacol 2014 Aug 15 2
17 25407413 Comparison of human and Drosophila atlastin GTPases. Protein Cell 2015 Feb 3
18 27615282 Lipoxin A<sub>4</sub> selectively programs the profile of M2 tumor-associated macrophages which favour control of tumor progression. Int J Cancer 2017 Jan 15 6
19 28602821 Timing and Reset Mechanism of GTP Hydrolysis-Driven Conformational Changes of Atlastin. Structure 2017 Jul 5 1
20 28718624 Covalent Enzyme Inhibition through Fluorosulfate Modification of a Noncatalytic Serine Residue. ACS Chem Biol 2017 Aug 18 3
21 29310658 The involvement of endoplasmic reticulum formation and protein synthesis efficiency in VCP- and ATL1-related neurological disorders. J Biomed Sci 2018 Jan 8 1
22 30287684 The atlastin membrane anchor forms an intramembrane hairpin that does not span the phospholipid bilayer. J Biol Chem 2018 Nov 30 1
23 30317802 [Role of MAPK signaling pathway in epithelial-mesenchymal transition of type II alveolar epithelial cells induced by Paraquat]. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 2018 Aug 20 1
24 30405845 Activated Tumor-infiltrating Fibroblasts Predict Worse Prognosis in Breast Cancer Patients. J Cancer 2018 1
25 31729196 Atlastin-1 modulates seizure activity and neuronal excitability. CNS Neurosci Ther 2020 Mar 1
26 31936571 Ferroptosis in Cancer Cell Biology. Cancers (Basel) 2020 Jan 9 2
27 31949826 The RhoA/ROCK signaling pathway affects the development of diabetic nephropathy resulting from the epithelial to mesenchymal transition. Int J Clin Exp Pathol 2018 1
28 31951565 The Antioxidant Role of Non-mitochondrial CoQ10: Mystery Solved! Cell Metab 2020 Jan 7 1
29 32135457 Atractylenolide I inhibits colorectal cancer cell proliferation by affecting metabolism and stemness via AKT/mTOR signaling. Phytomedicine 2020 Mar 1
30 32449465 Synthesis of oligodeoxyribonucleotides containing a tricyclic thio analogue of <i>O</i><sup>6</sup>-methylguanine and their recognition by MGMT and Atl1. Nucleosides Nucleotides Nucleic Acids 2020 3
31 32860809 Puerarin attenuates the endothelial-mesenchymal transition induced by oxidative stress in human coronary artery endothelial cells through PI3K/AKT pathway. Eur J Pharmacol 2020 Nov 5 2
32 32898324 Transfer of metastatic traits via miR-200c in extracellular vesicles derived from colorectal cancer stem cells is inhibited by atractylenolide I. Clin Transl Med 2020 Aug 1
33 32920707 ROS-Dependent Lipid Peroxidation and Reliant Antioxidant Ferroptosis-Suppressor-Protein 1 in Rheumatoid Arthritis: a Covert Clue for Potential Therapy. Inflammation 2021 Feb 3
34 33287888 Impaired lipid metabolism in astrocytes underlies degeneration of cortical projection neurons in hereditary spastic paraplegia. Acta Neuropathol Commun 2020 Dec 7 5
35 33781830 Exosomal miR-4443 promotes cisplatin resistance in non-small cell lung carcinoma by regulating FSP1 m6A modification-mediated ferroptosis. Life Sci 2021 Jul 1 2
36 34707002 CYP2J2<b>-</b>produced epoxyeicosatrienoic acids contribute to the ferroptosis resistance of pancreatic ductal adenocarcinoma in a PPAR<b>γ-</b>dependent manner. Zhong Nan Da Xue Xue Bao Yi Xue Ban 2021 Sept 28 2
37 34748909 Profiling the chemical nature of anti-oxytotic/ferroptotic compounds with phenotypic screening. Free Radic Biol Med 2021 Dec 2
38 34808209 A novel insertion mutation in atlastin 1 is associated with spastic quadriplegia, increased membrane tethering, and aberrant conformational switching. J Biol Chem 2022 Jan 3
39 35107212 Ferroptosis: regulation by competition between NRF2 and BACH1 and propagation of the death signal. FEBS J 2022 Feb 2 6
40 35256587 Plasma-activated medium induces ferroptosis by depleting FSP1 in human lung cancer cells. Cell Death Dis 2022 Mar 7 4
41 35395704 Metabolic Intervention Nanoparticles for Triple-Negative Breast Cancer Therapy via Overcoming FSP1-Mediated Ferroptosis Resistance. Adv Healthc Mater 2022 Apr 8 6
42 35420780 Targeted Intervention of NF2-YAP Signaling Axis in CD24-Overexpressing Cells Contributes to Encouraging Therapeutic Effects in TNBC. ACS Nano 2022 Apr 14 2
43 35459868 A targetable CoQ-FSP1 axis drives ferroptosis- and radiation-resistance in KEAP1 inactive lung cancers. Nat Commun 2022 Apr 22 6
44 35585057 Involvement of FSP1-CoQ<sub>10</sub>-NADH and GSH-GPx-4 pathways in retinal pigment epithelium ferroptosis. Cell Death Dis 2022 May 18 4
45 35598770 BMAL1 modulates smooth muscle cells phenotypic switch towards fibroblast-like cells and stabilizes atherosclerotic plaques by upregulating YAP1. Biochim Biophys Acta Mol Basis Dis 2022 Sep 1 2