retinoid X receptor alpha ; Homo sapiens






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1 1309942 9-cis retinoic acid stereoisomer binds and activates the nuclear receptor RXR alpha. Nature 1992 Jan 23 5
2 1310260 9-cis retinoic acid is a high affinity ligand for the retinoid X receptor. Cell 1992 Jan 24 6
3 1310350 Retinoid X receptor is an auxiliary protein for thyroid hormone and retinoic acid receptors. Nature 1992 Jan 30 3
4 1310351 Retinoid X receptor interacts with nuclear receptors in retinoic acid, thyroid hormone and vitamin D3 signalling. Nature 1992 Jan 30 5
5 1311101 Retinoid X receptor-COUP-TF interactions modulate retinoic acid signaling. Proc Natl Acad Sci U S A 1992 Feb 15 1
6 1312497 Characterization of three RXR genes that mediate the action of 9-cis retinoic acid. Genes Dev 1992 Mar 4
7 1321332 Repression by ARP-1 sensitizes apolipoprotein AI gene responsiveness to RXR alpha and retinoic acid. Mol Cell Biol 1992 Aug 4
8 1323763 Homodimer formation of retinoid X receptor induced by 9-cis retinoic acid. Nature 1992 Aug 13 3
9 1324421 Heterodimeric receptor complexes determine 3,5,3'-triiodothyronine and retinoid signaling specificities. Mol Endocrinol 1992 Jul 1
10 1324435 Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors. Nature 1992 Aug 27 2
11 1326406 Promoter context- and response element-dependent specificity of the transcriptional activation and modulating functions of retinoic acid receptors. Cell 1992 Sep 18 4
12 1327537 All-trans and 9-cis retinoic acid induction of CRABPII transcription is mediated by RAR-RXR heterodimers bound to DR1 and DR2 repeated motifs. Cell 1992 Oct 2 1
13 1328196 Identification of a novel retinoid-responsive element in the promoter region of the medium chain acyl-coenzyme A dehydrogenase gene. J Biol Chem 1992 Oct 5 1
14 1328295 Human skin levels of retinoic acid and cytochrome P-450-derived 4-hydroxyretinoic acid after topical application of retinoic acid in vivo compared to concentrations required to stimulate retinoic acid receptor-mediated transcription in vitro. J Clin Invest 1992 Oct 1
15 1328857 COUP orphan receptors are negative regulators of retinoic acid response pathways. Mol Cell Biol 1992 Oct 1
16 1328864 Terminal differentiation in keratinocytes involves positive as well as negative regulation by retinoic acid receptors and retinoid X receptors at retinoid response elements. Mol Cell Biol 1992 Nov 1
17 1328967 Identification of a unique nuclear receptor for 9-cis retinoic acid. Nutr Rev 1992 Aug 3
18 1331079 Triiodothyronine (T3) differentially affects T3-receptor/retinoic acid receptor and T3-receptor/retinoid X receptor heterodimer binding to DNA. J Biol Chem 1992 Nov 15 3
19 1333043 Activation of the phosphoenolpyruvate carboxykinase gene retinoic acid response element is dependent on a retinoic acid receptor/coregulator complex. Mol Cell Biol 1992 Dec 2
20 1335166 Retinoids selective for retinoid X receptor response pathways. Science 1992 Dec 18 3
21 1646397 A retinoic acid-responsive element in the apolipoprotein AI gene distinguishes between two different retinoic acid response pathways. Mol Cell Biol 1991 Jul 4
22 1648728 Retinoic acid is a negative regulator of AP-1-responsive genes. Proc Natl Acad Sci U S A 1991 Jul 15 1
23 1651173 A direct repeat in the cellular retinol-binding protein type II gene confers differential regulation by RXR and RAR. Cell 1991 Aug 9 7
24 1662118 RXR beta: a coregulator that enhances binding of retinoic acid, thyroid hormone, and vitamin D receptors to their cognate response elements. Cell 1991 Dec 20 1
25 7491109 A highly conserved region in the hormone-binding domain of the human vitamin D receptor contains residues vital for heterodimerization with retinoid X receptor and for transcriptional activation. Mol Endocrinol 1995 Sep 2
26 7556191 Involvement of retinoic acid receptor alpha in the stimulation of tissue-type plasminogen-activator gene expression in human endothelial cells. Eur J Biochem 1995 Sep 1 4
27 7565709 9-cis retinoic acid inhibition of activation-induced apoptosis is mediated via regulation of fas ligand and requires retinoic acid receptor and retinoid X receptor activation. Mol Cell Biol 1995 Oct 1
28 7565739 Adenovirus E1A functions as a cofactor for retinoic acid receptor beta (RAR beta) through direct interaction with RAR beta. Mol Cell Biol 1995 Nov 1
29 7566126 Polarity-specific activities of retinoic acid receptors determined by a co-repressor. Nature 1995 Oct 5 2
30 7575575 The T-box near the zinc fingers of the human vitamin D receptor is required for heterodimeric DNA binding and transactivation. Biochem Biophys Res Commun 1995 Oct 4 1
31 7575611 Antagonism of COUP-TF and PPAR alpha/RXR alpha on the activation of the malic enzyme gene promoter: modulation by 9-cis RA. Biochem Biophys Res Commun 1995 Oct 4 1
32 7576177 Regulation of H1(0) gene expression by nuclear receptors through an unusual response element: implications for regulation of cell proliferation. DNA Cell Biol 1995 Nov 3
33 7577963 Role of ligand in retinoid signaling. 9-cis-retinoic acid modulates the oligomeric state of the retinoid X receptor. Biochemistry 1995 Oct 24 4
34 7578026 On the role of ligand in retinoid signaling: positive cooperativity in the interactions of 9-cis retinoic acid with tetramers of the retinoid X receptor. Biochemistry 1995 Oct 31 5
35 7585485 Effects of vitamin D3 derivatives on growth, differentiation and apoptosis in tumoral colonic HT 29 cells: possible implication of intracellular calcium. Cancer Lett 1995 Oct 20 3
36 7597096 Activation of mammalian retinoid X receptors by the insect growth regulator methoprene. Proc Natl Acad Sci U S A 1995 Jun 20 3
37 7623814 A retinoic acid response element that overlaps an estrogen response element mediates multihormonal sensitivity in transcriptional activation of the lactoferrin gene. Mol Cell Biol 1995 Aug 4
38 7624356 Conditional site-specific recombination in mammalian cells using a ligand-dependent chimeric Cre recombinase. Proc Natl Acad Sci U S A 1995 Jul 18 1
39 7625727 Nuclear hormone receptors activate direct, inverted, and everted repeats. Ann N Y Acad Sci 1995 Jun 12 3
40 7636843 Synthesis and structure-activity relationships of stilbene retinoid analogs substituted with heteroaromatic carboxylic acids. J Med Chem 1995 Jul 21 1
41 7636877 Design and synthesis of potent retinoid X receptor selective ligands that induce apoptosis in leukemia cells. J Med Chem 1995 Aug 4 7
42 7641808 Effect of 9-cis-retinoic acid on growth and RXR expression in human breast cancer cells. Exp Cell Res 1995 Aug 1
43 7650690 Conformational effects on retinoid receptor selectivity. 2. Effects of retinoid bridging group on retinoid X receptor activity and selectivity. J Med Chem 1995 Aug 18 8
44 7654186 Retinoid receptors cause distortion of the retinoic acid response element in the phosphoenolpyruvate carboxykinase gene promoter. Biochem J 1995 Sep 1 4
45 7669070 Diminished teratogenicity of retinoid X receptor-selective synthetic retinoids. Biochem Pharmacol 1995 Aug 25 1
46 7672440 Transcriptional regulation of human thyroid hormone receptor beta 1 gene expression: effect of human retinoid X receptor and identification of a transcriptional silencer region. Mol Cell Endocrinol 1995 Apr 28 1
47 7691069 Retinoic acid receptor and retinoid X receptor expression in retinoic acid-resistant human tumor cell lines. Mol Carcinog 1993 1
48 7697779 Synthesis of 9E- and 9Z-locked retinoic acid analogs as ligands for RAR and RXR. Chem Pharm Bull (Tokyo) 1994 Dec 1
49 7700077 Potent vitamin D3 analogs: their abilities to enhance transactivation and to bind to the vitamin D3 response element. Leuk Res 1995 Mar 2
50 7705655 A novel pathway for vitamin A signaling mediated by RXR heterodimerization with NGFI-B and NURR1. Genes Dev 1995 Apr 1 2