surface glycoprotein ; Severe acute respiratory syndrome coronavirus 2






731 Article(s)
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1 32167180 The establishment of reference sequence for SARS-CoV-2 and variation analysis. J Med Virol 2020 Jun 1
2 32201080 Spike protein recognition of mammalian ACE2 predicts the host range and an optimized ACE2 for SARS-CoV-2 infection. Biochem Biophys Res Commun 2020 May 21 1
3 32225175 Structural basis of receptor recognition by SARS-CoV-2. Nature 2020 May 1
4 32245784 A highly conserved cryptic epitope in the receptor binding domains of SARS-CoV-2 and SARS-CoV. Science 2020 May 8 2
5 32293168 Rapid Detection of COVID-19 Causative Virus (SARS-CoV-2) in Human Nasopharyngeal Swab Specimens Using Field-Effect Transistor-Based Biosensor. ACS Nano 2020 Apr 28 2
6 32335456 The old but new: Can unfractioned heparin and low molecular weight heparins inhibit proteolytic activation and cellular internalization of SARS-CoV2 by inhibition of host cell proteases? Med Hypotheses 2020 Sep 1
7 32345140 Stilbene-based natural compounds as promising drug candidates against COVID-19. J Biomol Struct Dyn 2021 Jun 5
8 32362314 A Multibasic Cleavage Site in the Spike Protein of SARS-CoV-2 Is Essential for Infection of Human Lung Cells. Mol Cell 2020 May 21 1
9 32363391 Deducing the N- and O-glycosylation profile of the spike protein of novel coronavirus SARS-CoV-2. Glycobiology 2020 Dec 9 7
10 32366695 Site-specific glycan analysis of the SARS-CoV-2 spike. Science 2020 Jul 17 2
11 32374903 SARS-CoV-2 viral spike G614 mutation exhibits higher case fatality rate. Int J Clin Pract 2020 Aug 2
12 32404436 TMPRSS2 and TMPRSS4 promote SARS-CoV-2 infection of human small intestinal enterocytes. Sci Immunol 2020 May 13 1
13 32404529 Comparison of Severe Acute Respiratory Syndrome Coronavirus 2 Spike Protein Binding to ACE2 Receptors from Human, Pets, Farm Animals, and Putative Intermediate Hosts. J Virol 2020 Jul 16 1
14 32405156 Synergistic antiviral effect of hydroxychloroquine and azithromycin in combination against SARS-CoV-2: What molecular dynamics studies of virus-host interactions reveal. Int J Antimicrob Agents 2020 Aug 1
15 32475223 Antiviral effects of probiotic metabolites on COVID-19. J Biomol Struct Dyn 2021 Jul 5
16 32485251 A recombinant Lactobacillus plantarum strain expressing the spike protein of SARS-CoV-2. Int J Biol Macromol 2020 Oct 1 1
17 32518941 Identification of 22 N-glycosites on spike glycoprotein of SARS-CoV-2 and accessible surface glycopeptide motifs: Implications for vaccination and antibody therapeutics. Glycobiology 2021 Jan 9 2
18 32532094 The Anticoagulant Nafamostat Potently Inhibits SARS-CoV-2 S Protein-Mediated Fusion in a Cell Fusion Assay System and Viral Infection In Vitro in a Cell-Type-Dependent Manner. Viruses 2020 Jun 10 2
19 32545268 Potential of Flavonoid-Inspired Phytomedicines against COVID-19. Molecules 2020 Jun 11 1
20 32551648 The Discovery of a Putative Allosteric Site in the SARS-CoV-2 Spike Protein Using an Integrated Structural/Dynamic Approach. J Proteome Res 2020 Nov 6 1
21 32562764 Dual function of sialic acid in gastrointestinal SARS-CoV-2 infection. Environ Toxicol Pharmacol 2020 Oct 5
22 32579907 Paromomycin: A potential dual targeted drug effectively inhibits both spike (S1) and main protease of COVID-19. Int J Infect Dis 2020 Sep 3
23 32587973 The D614G mutation in the SARS-CoV-2 spike protein reduces S1 shedding and increases infectivity. bioRxiv 2020 Jun 12 4
24 32589459 Ocular Surface Expression of SARS-CoV-2 Receptors. Ocul Immunol Inflamm 2020 Jul 3 1
25 32593613 Testing of natural products in clinical trials targeting the SARS-CoV-2 (Covid-19) viral spike protein-angiotensin converting enzyme-2 (ACE2) interaction. Biochem Pharmacol 2020 Aug 1
26 32605194 Coronavirus Disease Pandemic (COVID-19): Challenges and a Global Perspective. Pathogens 2020 Jun 28 1
27 32637953 A glycan cluster on the SARS-CoV-2 spike ectodomain is recognized by Fab-dimerized glycan-reactive antibodies. bioRxiv 2020 Jun 30 1
28 32638018 Single-cell analysis of SARS-CoV-2 receptor ACE2 and spike protein priming expression of proteases in the human heart. Cardiovasc Res 2020 Aug 1 1
29 32654533 Design of engineered surfaces for prospective detection of SARS-CoV-2 using quartz crystal microbalance-based techniques. Expert Rev Proteomics 2020 Jun 1
30 32656452 Impact of Thiol-Disulfide Balance on the Binding of Covid-19 Spike Protein with Angiotensin-Converting Enzyme 2 Receptor. ACS Omega 2020 Jul 7 5
31 32672061 Evidence supporting the use of peptides and peptidomimetics as potential SARS-CoV-2 (COVID-19) therapeutics. Future Med Chem 2020 Sep 4
32 32681121 ACE2 gene variants may underlie interindividual variability and susceptibility to COVID-19 in the Italian population. Eur J Hum Genet 2020 Nov 1
33 32696720 Antimalarial-agent artemisinin and derivatives portray more potent binding to Lys353 and Lys31-binding hotspots of SARS-CoV-2 spike protein than hydroxychloroquine: potential repurposing of artenimol for COVID-19. J Biomol Struct Dyn 2021 Oct 7
34 32698689 Targeting SARS-CoV-2 spike protein of COVID-19 with naturally occurring phytochemicals: an <i>in silico</i> study for drug development. J Biomol Struct Dyn 2021 Oct 2
35 32699853 SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2. bioRxiv 2020 Jul 14 12
36 32703906 Structure-based design of prefusion-stabilized SARS-CoV-2 spikes. Science 2020 Sep 18 1
37 32729392 Antiviral potential of some novel structural analogs of standard drugs repurposed for the treatment of COVID-19. J Biomol Struct Dyn 2021 Oct 3
38 32736596 ACCORD: A Multicentre, Seamless, Phase 2 Adaptive Randomisation Platform Study to Assess the Efficacy and Safety of Multiple Candidate Agents for the Treatment of COVID-19 in Hospitalised Patients: A structured summary of a study protocol for a randomised controlled trial. Trials 2020 Jul 31 2
39 32737467 A thermostable, closed SARS-CoV-2 spike protein trimer. Nat Struct Mol Biol 2020 Oct 3
40 32741259 Identification of potential anti-TMPRSS2 natural products through homology modelling, virtual screening and molecular dynamics simulation studies. J Biomol Struct Dyn 2020 Aug 3 2
41 32743575 Simulations support the interaction of the SARS-CoV-2 spike protein with nicotinic acetylcholine receptors. bioRxiv 2020 Sep 14 1
42 32746720 Deciphering the protein motion of S1 subunit in SARS-CoV-2 spike glycoprotein through integrated computational methods. J Biomol Struct Dyn 2021 Oct 1
43 32753553 Engineering human ACE2 to optimize binding to the spike protein of SARS coronavirus 2. Science 2020 Sep 4 1
44 32757981 <i>In silico</i> Potential of Approved Antimalarial Drugs for Repurposing Against COVID-19. OMICS 2020 Oct 2
45 32762417 Effect of mutation on structure, function and dynamics of receptor binding domain of human SARS-CoV-2 with host cell receptor ACE2: a molecular dynamics simulations study. J Biomol Struct Dyn 2021 Nov 1
46 32768503 In silico pharmacokinetic and molecular docking studies of natural flavonoids and synthetic indole chalcones against essential proteins of SARS-CoV-2. Eur J Pharmacol 2020 Nov 5 2
47 32770567 Epigallocatechin gallate and theaflavin gallate interaction in SARS-CoV-2 spike-protein central channel with reference to the hydroxychloroquine interaction: Bioinformatics and molecular docking study. Drug Dev Res 2021 Feb 9
48 32772313 Anthraquinone Derivatives as an Immune Booster and their Therapeutic Option Against COVID-19. Nat Prod Bioprospect 2020 Oct 3
49 32793181 Quinolines-Based SARS-CoV-2 3CLpro and RdRp Inhibitors and Spike-RBD-ACE2 Inhibitor for Drug-Repurposing Against COVID-19: An <i>in silico</i> Analysis. Front Microbiol 2020 2
50 32793901 Structural analysis of full-length SARS-CoV-2 spike protein from an advanced vaccine candidate. bioRxiv 2020 Aug 6 1