synaptotagmin 1 ; Homo sapiens






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1 7479869 Role of the C2B domain of synaptotagmin in vesicular release and recycling as determined by specific antibody injection into the squid giant synapse preterminal. Proc Natl Acad Sci U S A 1995 Nov 7 10
2 7540672 Synaptic vesicle dynamics in living cultured hippocampal neurons visualized with CY3-conjugated antibodies directed against the lumenal domain of synaptotagmin. J Neurosci 1995 Jun 2
3 7697723 Structure of the first C2 domain of synaptotagmin I: a novel Ca2+/phospholipid-binding fold. Cell 1995 Mar 24 1
4 7791877 Ca(2+)-dependent and -independent activities of neural and non-neural synaptotagmins. Nature 1995 Jun 15 2
5 7951320 Identification of novel genes, SYT and SSX, involved in the t(X;18)(p11.2;q11.2) translocation found in human synovial sarcoma. Nat Genet 1994 Aug 7
6 7961798 Ca(2+)-dependent conformational change in synaptotagmin I. J Biol Chem 1994 Nov 18 3
7 8253763 A single C2 domain from synaptotagmin I is sufficient for high affinity Ca2+/phospholipid binding. J Biol Chem 1993 Dec 15 4
8 8454654 Phosphorylation of synaptotagmin I by casein kinase II. J Biol Chem 1993 Mar 25 9
9 8815873 Mobility of synaptic vesicles in nerve endings monitored by recovery from photobleaching of synaptic vesicle-associated fluorescence. J Neurosci 1996 Oct 1 1
10 8858951 Calcium-dependent self-association of synaptotagmin I. J Neurochem 1996 Oct 8
11 8901523 Mirror image motifs mediate the interaction of the COOH terminus of multiple synaptotagmins with the neurexins and calmodulin. Biochemistry 1996 Oct 29 1
12 9020139 Selective photoaffinity labeling of the inositol polyphosphate binding C2B domains of synaptotagmins. J Biol Chem 1997 Feb 14 14
13 9130775 Roles of synaptotagmin C2 domains in neurotransmitter secretion and inositol high-polyphosphate binding at mammalian cholinergic synapses. Neuroscience 1997 Apr 1
14 9162066 The evolutionary pressure to inactivate. A subclass of synaptotagmins with an amino acid substitution that abolishes Ca2+ binding. J Biol Chem 1997 May 30 3
15 9303303 Direct interaction of the calcium sensor protein synaptotagmin I with a cytoplasmic domain of the alpha1A subunit of the P/Q-type calcium channel. EMBO J 1997 Aug 1 3
16 9390409 Assignment of the 1H, 15N and 13C resonances of the calcium-free and calcium-bound forms of the first C2-domain of synaptotagmin I. J Biomol NMR 1997 Oct 5
17 9556426 Detection of the SYT-SSX chimeric RNA of synovial sarcoma in paraffin-embedded tissue and its application in problematic cases. Mod Pathol 1998 Jan 3
18 9668093 Calcium-dependent membrane penetration is a hallmark of the C2 domain of cytosolic phospholipase A2 whereas the C2A domain of synaptotagmin binds membranes electrostatically. J Biol Chem 1998 Jul 24 1
19 9670009 Ca2+ binding to synaptotagmin: how many Ca2+ ions bind to the tip of a C2-domain? EMBO J 1998 Jul 15 1
20 9688183 Detection of the SYT-SSX fusion transcripts in formaldehyde-fixed, paraffin-embedded tissue: a reverse transcription polymerase chain reaction amplification assay useful in the diagnosis of synovial sarcoma. Mod Pathol 1998 Jul 2
21 9730811 Mechanism of phospholipid binding by the C2A-domain of synaptotagmin I. Biochemistry 1998 Sep 8 3
22 9819203 Solution structures of the Ca2+-free and Ca2+-bound C2A domain of synaptotagmin I: does Ca2+ induce a conformational change? Biochemistry 1998 Nov 17 1
23 9846971 Detection of SYT-SSX fusion transcripts in synovial sarcoma by reverse transcription-polymerase chain reaction using archival paraffin-embedded tissues. Am J Pathol 1998 Dec 4
24 10217560 Primary synovial sarcoma of the lung: report of two cases confirmed by molecular detection of SYT-SSX fusion gene transcripts. Histopathology 1999 Mar 2
25 10594136 Occult pulmonary synovial sarcoma confirmed by molecular techniques. Pediatr Dev Pathol 2000 Jan-Feb 1
26 10715114 Specificity of Ca2+-dependent protein interactions mediated by the C2A domains of synaptotagmins. Biochemistry 2000 Mar 21 2
27 10811903 Calcium triggers an intramolecular association of the C2 domains in synaptotagmin. Proc Natl Acad Sci U S A 2000 May 23 1
28 10889911 Detection of SYT-SSX fusion transcripts in both epithelial and spindle cell areas of biphasic synovial sarcoma using laser capture microdissection. Mol Pathol 2000 Apr 2
29 10933784 Binding kinetics and ligand specificity for the interactions of the C2B domain of synaptogmin II with inositol polyphosphates and phosphoinositides. Biochemistry 2000 Aug 15 1
30 10935650 Primary synovial sarcoma of the kidney. Am J Surg Pathol 2000 Aug 2
31 11011146 Calcium-dependent and -independent hetero-oligomerization in the synaptotagmin family. J Biochem 2000 Oct 3
32 11107054 Synovial sarcomas of three children in the first decade: clinicopathological and molecular findings. Pathol Int 2000 Oct 2
33 11172303 Detection of the synovial sarcoma translocation t(X;18) (SYT;SSX) in paraffin-embedded tissues using reverse transcriptase-polymerase chain reaction: a reliable and powerful diagnostic tool for pathologists. A molecular analysis of 221 mesenchymal tumors fixed in different fixatives. Hum Pathol 2001 Jan 3
34 11224869 Intraneural monophasic synovial sarcoma: a case report. Spine (Phila Pa 1976) 2001 Feb 1 1
35 11308259 Identification of a novel spliced variant of the SYT gene expressed in normal tissues and in synovial sarcoma. Br J Cancer 2001 Apr 20 1
36 11309201 Expression and localisation of synaptotagmin isoforms in endocrine beta-cells: their function in insulin exocytosis. J Cell Sci 2001 May 2
37 11422798 Primary synovial sarcoma of the kidney: Report of a case confirmed by molecular detection of the SYT-SSX2 fusion transcripts. Pathol Int 2001 May 2
38 11432880 Copper induces the assembly of a multiprotein aggregate implicated in the release of fibroblast growth factor 1 in response to stress. J Biol Chem 2001 Jul 6 4
39 11438518 Direct interaction of the Rab3 effector RIM with Ca2+ channels, SNAP-25, and synaptotagmin. J Biol Chem 2001 Aug 31 1
40 11447211 The top loops of the C(2) domains from synaptotagmin and phospholipase A(2) control functional specificity. J Biol Chem 2001 Aug 24 3
41 11514560 Mechanism of the SDS-resistant synaptotagmin clustering mediated by the cysteine cluster at the interface between the transmembrane and spacer domains. J Biol Chem 2001 Oct 26 7
42 11519826 The comparative release of FGF1 by hypoxia and temperature stress. Growth Factors 2001 1
43 11561755 Identification of syt-ssx fusion transcripts in both epithelial and spindle cell components of biphasic synovial sarcoma in small tissue samples isolated by membrane-based laser microdissection. Virchows Arch 2001 Aug 2
44 11689890 Non-invasive detection of apoptosis using magnetic resonance imaging and a targeted contrast agent. Nat Med 2001 Nov 1
45 11754837 Three-dimensional structure of the synaptotagmin 1 C2B-domain: synaptotagmin 1 as a phospholipid binding machine. Neuron 2001 Dec 20 2
46 11815451 Role of electrostatic and hydrophobic interactions in Ca(2+)-dependent phospholipid binding by the C(2)A-domain from synaptotagmin I. Diabetes 2002 Feb 1
47 11826189 Detection of SYT-SSX fusion transcripts in archival synovial sarcomas by real-time reverse transcriptase-polymerase chain reaction. J Mol Diagn 2002 Feb 2
48 11854597 Molecular detection of the synovial sarcoma translocation t(X;18) by real-time polymerase chain reaction in paraffin-embedded material. Diagn Mol Pathol 2002 Mar 1
49 11866984 [Detection of SYT-SSX fusion gene in paraffin-embedded tissues and its clinicopathologic significance for synovial sarcoma]. Zhonghua Bing Li Xue Za Zhi 2001 Dec 3
50 11866985 [Detection and analysis of SYT-SSX fusion gene in synovial sarcoma]. Zhonghua Bing Li Xue Za Zhi 2001 Dec 1