Arsenic Trioxide






1388 Article(s)
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1 2540587 Lack of effectiveness of D-penicillamine in experimental arsenic poisoning. Vet Hum Toxicol 1989 Feb 1
2 5847391 [Supplement to a 1st plea on behalf of arsenous anhydride. Is the condemnation of arsenic unjust?]. Actual Odontostomatol (Paris) 1965 Sep 1
3 6129183 [Relationship between arsenic-induced hypothermia and brain monoamines. (2). The roles of noradrenaline and dopamine]. Nihon Yakurigaku Zasshi 1982 Aug 1
4 6719100 The speciation of the chemical forms of arsenic in the biological monitoring of exposure to inorganic arsenic. Sci Total Environ 1984 Mar 15 1
5 7747285 Lung toxicity of hard metal particles and production of interleukin-1, tumor necrosis factor-alpha, fibronectin, and cystatin-c by lung phagocytes. Toxicol Appl Pharmacol 1995 May 3
6 8704214 In vitro studies on cellular and molecular mechanisms of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia: As2O3 induces NB4 cell apoptosis with downregulation of Bcl-2 expression and modulation of PML-RAR alpha/PML proteins. Blood 1996 Aug 1 12
7 8986606 The PML and PML/RARalpha domains: from autoimmunity to molecular oncology and from retinoic acid to arsenic. Exp Cell Res 1996 Dec 15 1
8 9129041 Use of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia (APL): I. As2O3 exerts dose-dependent dual effects on APL cells. Blood 1997 May 1 1
9 9129042 Use of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia (APL): II. Clinical efficacy and pharmacokinetics in relapsed patients. Blood 1997 May 1 4
10 9395660 Characterization of differing effects caused by homeopathically prepared and conventional dilutions using cytochrome P450 2E1 and other enzymes as detection systems. J Altern Complement Med 1996 Summer 1
11 9427741 Conjugation with the ubiquitin-related modifier SUMO-1 regulates the partitioning of PML within the nucleus. EMBO J 1998 Jan 2 3
12 9450572 Arsenic trioxide as an inducer of apoptosis and loss of PML/RAR alpha protein in acute promyelocytic leukemia cells. J Natl Cancer Inst 1998 Jan 21 2
13 9535176 Acute promyelocytic leukemia: cellular and molecular basis of differentiation and apoptosis. Pharmacol Ther 1997 Oct-Dec 4
14 9596679 Combined arsenic and retinoic acid treatment enhances differentiation and apoptosis in arsenic-resistant NB4 cells. Blood 1998 Jun 1 8
15 9716575 Arsenic trioxide and melarsoprol induce programmed cell death in myeloid leukemia cell lines and function in a PML and PML-RARalpha independent manner. Blood 1998 Sep 1 14
16 9737686 The induction of apoptosis and cell cycle arrest by arsenic trioxide in lymphoid neoplasms. Leukemia 1998 Sep 2
17 9772451 [Double effects of arsenic trioxide (As2O3) on acute promyelocytic leukemic cell line]. Zhonghua Yi Xue Za Zhi 1997 Jul 6
18 9801394 Complete remission after treatment of acute promyelocytic leukemia with arsenic trioxide. N Engl J Med 1998 Nov 5 4
19 9834237 Trivalent antimonials induce degradation of the PML-RAR oncoprotein and reorganization of the promyelocytic leukemia nuclear bodies in acute promyelocytic leukemia NB4 cells. Blood 1998 Dec 1 5
20 10023688 Retinoic acid, but not arsenic trioxide, degrades the PLZF/RARalpha fusion protein, without inducing terminal differentiation or apoptosis, in a RA-therapy resistant t(11;17)(q23;q21) APL patient. Oncogene 1999 Jan 28 1
21 10190895 Retinoic acid and arsenic synergize to eradicate leukemic cells in a mouse model of acute promyelocytic leukemia. J Exp Med 1999 Apr 5 1
22 10328107 Apoptosis and growth inhibition in malignant lymphocytes after treatment with arsenic trioxide at clinically achievable concentrations. J Natl Cancer Inst 1999 May 5 2
23 10373566 PIC-1/SUMO-1-modified PML-retinoic acid receptor alpha mediates arsenic trioxide-induced apoptosis in acute promyelocytic leukemia. Mol Cell Biol 1999 Jul 12
24 10382944 Arsenic trioxide induces apoptosis of myeloid leukemia cells by activation of caspases. Med Oncol 1999 Apr 2
25 10400422 Tissue factors on acute promyelocytic leukemia and endothelial cells are differently regulated by retinoic acid, arsenic trioxide and chemotherapeutic agents. Leukemia 1999 Jul 5
26 10428472 Arsenic trioxide induces apoptosis in neuroblastoma cell lines through the activation of caspase 3 in vitro. FEBS Lett 1999 Jul 16 2
27 10448126 Low levels of arsenic trioxide stimulate proliferative signals in primary vascular cells without activating stress effector pathways. Toxicol Appl Pharmacol 1999 Aug 15 3
28 10477740 Arsenic trioxide selectively induces acute promyelocytic leukemia cell apoptosis via a hydrogen peroxide-dependent pathway. Blood 1999 Sep 15 2
29 10558879 Effect of arsenic trioxide on cell cycle arrest in head and neck cancer cell line PCI-1. Biochem Biophys Res Commun 1999 Nov 19 3
30 10581825 Efficacy of a potentized homoeopathic drug (Arsenicum Album-30) in reducing genotoxic effects produced by arsenic trioxide in mice: II. Comparative efficacy of an antibiotic, actinomycin D alone and in combination with either of two microdoses. Complement Ther Med 1999 Sep 4
31 10615238 Induction of apoptosis and inhibition of human gastric cancer MGC-803 cell growth by arsenic trioxide. Eur J Cancer 1999 Aug 1
32 10639594 The alteration of mitochondria is an early event of arsenic trioxide induced apoptosis in esophageal carcinoma cells. Int J Mol Med 2000 Feb 1
33 10648417 Arsenic induces apoptosis of multidrug-resistant human myeloid leukemia cells that express Bcr-Abl or overexpress MDR, MRP, Bcl-2, or Bcl-x(L). Blood 2000 Feb 1 1
34 10673743 Arsenic trioxide-induced apoptosis and differentiation are associated respectively with mitochondrial transmembrane potential collapse and retinoic acid signaling pathways in acute promyelocytic leukemia. Leukemia 2000 Feb 1
35 10674975 In vitro exposure of acute promyelocytic leukemia cells to arsenic trioxide (As2O3) induces the solitary expression of CD66c (NCA-50/90), a member of the CEA family. Tissue Antigens 1999 Dec 7
36 10712780 [Antitumor effect of arsenic trioxide on mice experimental liver cancer]. Zhonghua Gan Zang Bing Za Zhi 2000 Feb 2
37 10721769 Arsenic-induced apoptosis in malignant cells in vitro. Leuk Lymphoma 2000 Mar 2
38 10811458 The effects of arsenic trioxide (As2O3) on human megakaryocytic leukemia cell lines. With a comparison of its effects on other cell lineages. Leuk Lymphoma 2000 Jun 3
39 10830735 Arsenic trioxide therapy for relapsed acute promyelocytic leukemia: an useful salvage therapy. Leuk Lymphoma 2000 Jul 3
40 10841286 As2O3 induces apoptosis of the human B lymphoma cell line MBC-1. J Biol Regul Homeost Agents 2000 Apr-Jun 6
41 10850458 Arsenic trioxide-mediated growth inhibition in MC/CAR myeloma cells via cell cycle arrest in association with induction of cyclin-dependent kinase inhibitor, p21, and apoptosis. Cancer Res 2000 Jun 1 11
42 10910048 BCR-ABL mediates arsenic trioxide-induced apoptosis independently of its aberrant kinase activity. Cancer Res 2000 Jul 1 12
43 10942401 Arsenic trioxide induces dose- and time-dependent apoptosis of endothelium and may exert an antileukemic effect via inhibition of angiogenesis. Blood 2000 Aug 15 1
44 10954752 Retinoic acid (RA) and As2O3 treatment in transgenic models of acute promyelocytic leukemia (APL) unravel the distinct nature of the leukemogenic process induced by the PML-RARalpha and PLZF-RARalpha oncoproteins. Proc Natl Acad Sci U S A 2000 Aug 29 8
45 11021749 Involvement of CD95-independent caspase 8 activation in arsenic trioxide-induced apoptosis. Leukemia 2000 Oct 7
46 11068345 Efficacy of a potentized homeopathic drug (Arsenicum-Aalbum-30) in reducing cytotoxic effects produced by arsenic trioxide in mice: IV. Pathological changes, protein profiles, and content of DNA and RNA. Complement Ther Med 2000 Sep 1
47 11133770 Combined effect of all-trans retinoic acid and arsenic trioxide in acute promyelocytic leukemia cells in vitro and in vivo. Blood 2001 Jan 1 4
48 11135700 [An experimental study on arsenic trioxide-selectively induced human hepatocarcinoma cell lines apoptosis and its related genes]. Zhonghua Gan Zang Bing Za Zhi 2000 Dec 2
49 11146441 Arsenic trioxide induces apoptosis in human gastric cancer cells through up-regulation of p53 and activation of caspase-3. Int J Cancer 2001 Jan 15 2
50 11150309 Opposite effect of NF-kappa B and c-Jun N-terminal kinase on p53-independent GADD45 induction by arsenite. J Biol Chem 2001 Apr 6 19