1 | 1283698 | Agonist-antagonist interactions in the skin: comparison of effects of loratadine and cetirizine on skin vascular responses to prick tests with histamine and substance P. | J Dermatol Sci | 1992 Nov |
1 |
2 | 1357858 | Effects of antihistamines on cutaneous reactions and influx of eosinophils after local injection of PAF, kallikrein, compound 48/80 and histamine in patients with chronic urticaria and healthy subjects. | Acta Derm Venereol | 1992 |
1 |
3 | 1534660 | Evaluation of loratadine as an inducer of liver microsomal cytochrome P450 in rats and mice. | Biochem Pharmacol | 1992 May 28 |
2 |
4 | 1967919 | Comparative effects of loratadine and terfenadine in the treatment of chronic idiopathic urticaria. | Ann Allergy | 1990 Feb |
1 |
5 | 1977506 | Histamine and asthma: an appraisal based on specific H1-receptor antagonism. | Clin Exp Allergy | 1990 Aug |
1 |
6 | 2523301 | Loratadine. A preliminary review of its pharmacodynamic properties and therapeutic efficacy. | Drugs | 1989 Jan |
1 |
7 | 2568212 | Nonsedating histamine H1-receptor antagonists. | Clin Pharm | 1989 May |
1 |
8 | 7510965 | In vitro inhibition, by loratadine and descarboxyethoxyloratadine, of histamine release from human basophils, and of histamine release and intracellular calcium fluxes in rat basophilic leukemia cells (RBL-2H3). | Biochem Pharmacol | 1994 Mar 2 |
6 |
9 | 7542675 | Loratadine reduces allergen-induced mucosal output of alpha 2-macroglobulin and tryptase in allergic rhinitis. | J Allergy Clin Immunol | 1995 Jul |
4 |
10 | 7581058 | [Effect of loratadine, selective antagonist of histamine H1 receptors, on histamine-induced bronchoconstriction]. | Pneumonol Alergol Pol | 1995 |
1 |
11 | 7677235 | Inhibitory activity of loratadine and descarboethoxyloratadine on expression of ICAM-1 and HLA-DR by nasal epithelial cells. | Allergy | 1995 Mar |
1 |
12 | 8281352 | The effect of loratadine on activated cells of the nasal mucosa in patients with allergic rhinitis. | J Investig Allergol Clin Immunol | 1993 Jul-Aug |
3 |
13 | 8615885 | Identification of human liver cytochrome P450 enzymes that metabolize the nonsedating antihistamine loratadine. Formation of descarboethoxyloratadine by CYP3A4 and CYP2D6. | Biochem Pharmacol | 1996 Jan 26 |
9 |
14 | 9179431 | Loratadine and desethoxylcarbonyl-loratadine inhibit the immunological release of mediators from human Fc epsilon RI+ cells. | Clin Exp Allergy | 1997 May |
8 |
15 | 9271355 | Interactions of the nonsedating antihistamine loratadine with a Kv1.5-type potassium channel cloned from human heart. | Mol Pharmacol | 1997 Aug |
5 |
16 | 9349397 | Block of human cardiac Kv1.5 channels by loratadine: voltage-, time- and use-dependent block at concentrations above therapeutic levels. | Cardiovasc Res | 1997 Aug |
4 |
17 | 9360756 | Reduction of soluble ICAM-1 levels in nasal secretion by H1-blockers in seasonal allergic rhinitis. | Allergy | 1997 Oct |
2 |
18 | 9383258 | Loratadine treatment of rhinitis due to pollen allergy reduces epithelial ICAM-1 expression. | Clin Exp Allergy | 1997 Oct |
5 |
19 | 9384491 | Effect of descarboethoxyloratadine, the major metabolite of loratadine, on the human cardiac potassium channel Kv1.5. | Br J Pharmacol | 1997 Nov |
1 |
20 | 9618706 | [Histamine in the pathogenesis of asthma]. | Nihon Yakurigaku Zasshi | 1998 Apr |
1 |
21 | 9636821 | Loratadine reduces the expression of ICAM-1. | Allergy | 1998 May |
1 |
22 | 9658196 | Molecular basis for the lack of HERG K+ channel block-related cardiotoxicity by the H1 receptor blocker cetirizine compared with other second-generation antihistamines. | Mol Pharmacol | 1998 Jul |
1 |
23 | 10101740 | Inhibitory effect of loratadine on leukotriene B4 production by neutrophils either alone or during interaction with human airway epithelial cells. | Pulm Pharmacol Ther | 1998 |
2 |
24 | 10400845 | Effect of loratadine on nitrogen dioxide-induced changes in electrical resistance and release of inflammatory mediators from cultured human bronchial epithelial cells. | J Allergy Clin Immunol | 1999 Jul |
1 |
25 | 10563471 | Differential IL-10 receptor gene expression in acute versus chronic atopic eczema. Modulation by immunosuppressive drugs and cytokines in normal cultured keratinocytes. | Inflamm Res | 1999 Oct |
1 |
26 | 10597864 | Blockade of cardiac potassium and other channels by antihistamines. | Drug Saf | 1999 |
1 |
27 | 10597902 | In vitro inhibition of human liver drug metabolizing enzymes by second generation antihistamines. | Chem Biol Interact | 1999 Nov 15 |
8 |
28 | 10604956 | Loratadine blockade of K(+) channels in human heart: comparison with terfenadine under physiological conditions. | J Pharmacol Exp Ther | 2000 Jan |
1 |
29 | 10633171 | Constitutive activity of the histamine H(1) receptor reveals inverse agonism of histamine H(1) receptor antagonists. | Eur J Pharmacol | 2000 Jan 3 |
2 |
30 | 10772385 | Inhibition of cytokine secretion from human leukemic mast cells and basophils by H1- and H2-receptor antagonists. | Exp Dermatol | 2000 Apr |
1 |
31 | 10800633 | Preclinical pharmacology of desloratadine, a selective and nonsedating histamine H1 receptor antagonist. 1st communication: receptor selectivity, antihistaminic activity, and antiallergenic effects. | Arzneimittelforschung | 2000 Apr |
3 |
32 | 10858871 | Preclinical pharmacology of desloratadine, a selective and nonsedating histamine H1 receptor antagonist. 2nd communication: lack of central nervous system and cardiovascular effects. | Arzneimittelforschung | 2000 May |
2 |
33 | 10959557 | In vitro inhibitory effect of rupatadine on histamine and TNF-alpha release from dispersed canine skin mast cells and the human mast cell line HMC-1. | Inflamm Res | 2000 Jul |
2 |
34 | 11179434 | Cloning and pharmacological characterization of a fourth histamine receptor (H(4)) expressed in bone marrow. | Mol Pharmacol | 2001 Mar |
1 |
35 | 11240972 | Loratadine and terfenadine interaction with nefazodone: Both antihistamines are associated with QTc prolongation. | Clin Pharmacol Ther | 2001 Mar |
2 |
36 | 11432448 | Synergistic antiallergic activity of combined histamine H1- and cysteinyl leukotriene1-receptor blockade in human bronchus. | Life Sci | 2001 May 11 |
1 |
37 | 11454724 | Evaluation of the interaction of loratadine and desloratadine with P-glycoprotein. | Drug Metab Dispos | 2001 Aug |
2 |
38 | 11496238 | Effect of desloratadine and loratadine on rhinovirus-induced intercellular adhesion molecule 1 upregulation and promoter activation in respiratory epithelial cells. | J Allergy Clin Immunol | 2001 Aug |
5 |
39 | 11502723 | In vitro characterization of the inhibition profile of loratadine, desloratadine, and 3-OH-desloratadine for five human cytochrome P-450 enzymes. | Drug Metab Dispos | 2001 Sep |
5 |
40 | 11505807 | Antihistamines and serum adhesion molecule levels. | Allerg Immunol (Paris) | 2001 Jun |
2 |
41 | 11763722 | Effect of specific immunotherapy versus loratadine on serum adhesion molecules. | Allerg Immunol (Paris) | 2001 Oct |
2 |
42 | 12062662 | LC determination of loratadine and related impurities. | J Pharm Biomed Anal | 2002 Jun 20 |
1 |
43 | 12584158 | P-glycoprotein limits the brain penetration of nonsedating but not sedating H1-antagonists. | Drug Metab Dispos | 2003 Mar |
1 |
44 | 12768222 | Desloratadine: A preclinical and clinical overview. | Drugs Today (Barc) | 2001 Apr |
1 |
45 | 12789223 | Pregnancy outcome after gestational exposure to loratadine or antihistamines: a prospective controlled cohort study. | J Allergy Clin Immunol | 2003 Jun |
1 |
46 | 12962522 | Desloratadine: an update of its efficacy in the management of allergic disorders. | Drugs | 2003 |
1 |
47 | 14520518 | Comparison of the effects of desloratadine and levocetirizine on histamine-induced wheal, flare and itch in human skin. | Inflamm Res | 2003 Oct |
1 |
48 | 14681337 | Human liver aldehyde oxidase: inhibition by 239 drugs. | J Clin Pharmacol | 2004 Jan |
1 |
49 | 15932952 | Effect of cyp2d6*10 allele on the pharmacokinetics of loratadine in chinese subjects. | Drug Metab Dispos | 2005 Sep |
8 |
50 | 16076650 | Circadian time-dependent differences in murine tolerance to the antihistaminic agent loratadine. | Chronobiol Int | 2005 |
1 |