YM 022






21 Article(s)
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1 7491961 Gastrin receptor antagonist YM022 prevents hypersecretion after long-term acid suppression. Am J Physiol 1995 Nov 1
2 7932178 YM022 [(R)-1-[2,3-dihydro-1-(2'-methylphenacyl)-2-oxo-5-phenyl- 1H-1,4-benzodiazepin-3-yl]-3-(3-methylphenyl)urea], a potent and selective gastrin/cholecystokinin-B receptor antagonist, prevents gastric and duodenal lesions in rats. J Pharmacol Exp Ther 1994 Sep 2
3 8698625 Antiproliferative effect of a novel cholecystokinin-B/gastrin receptor antagonist, YM022. Jpn J Cancer Res 1996 Jul 2
4 8886928 Antagonistic effect of YM022, an antiulcer agent in rats, on human cholecystokinin (CCK)B/gastrin receptor. Jpn J Pharmacol 1996 Aug 1
5 9125636 YM022, a potent and selective gastrin/CCK-B receptor antagonist, inhibits peptone meal-induced gastric acid secretion in Heidenhain pouch dogs. Dig Dis Sci 1997 Apr 1
6 9331153 Role of gastrin/CCK-B receptor in the regulation of gastric acid secretion in rat. Dig Dis Sci 1997 Sep 2
7 9584331 Sustained cholecystokinin-B/gastrin receptor blockade does not impair basal or histamine-stimulated acid secretion in chronic gastric fistula rats. Pharmacol Toxicol 1998 Apr 1
8 9646057 YM022, a highly potent and selective CCKB antagonist inhibiting gastric acid secretion in the rat, the cat and isolated rabbit glands. Fundam Clin Pharmacol 1998 1
9 10821801 Long-lasting cholecystokinin(2) receptor blockade after a single subcutaneous injection of YF476 or YM022. Br J Pharmacol 2000 Jun 2
10 10961714 Acid secretory changes in streptozotocin-diabetic rats: different responses to various secretagogues. Dig Dis Sci 2000 Jul 1
11 12388195 Gastrin enhances gastric mucosal integrity through cyclooxygenase-2 upregulation in rats. Am J Physiol Gastrointest Liver Physiol 2002 Dec 1
12 12921485 New molecular targets for treatment of peptic ulcer disease. Drugs 2003 1
13 21334366 Formalin-induced long-term secondary allodynia and hyperalgesia are maintained by descending facilitation. Pharmacol Biochem Behav 2011 May 1
14 21354865 Descending facilitatory pathways from the rostroventromedial medulla mediate naloxone-precipitated withdrawal in morphine-dependent rats. J Pain 2011 Jun 1
15 24101389 Gastrin promotes intestinal polyposis through cholecystokinin-B receptor-mediated proliferative signaling and fostering tumor microenvironment. J Physiol Pharmacol 2013 Aug 2
16 25707915 The Pronociceptive Effect of Paradoxical Sleep Deprivation in Rats: Evidence for a Role of Descending Pain Modulation Mechanisms. Mol Neurobiol 2016 Apr 1
17 29717112 Gastrin stimulates pancreatic cancer cell directional migration by activating the Gα12/13-RhoA-ROCK signaling pathway. Exp Mol Med 2018 May 1 1
18 31430329 Islets from human donors with higher but not lower hemoglobin A1c levels respond to gastrin treatment in vitro. PLoS One 2019 6
19 33952826 Rapid Increase of Gastrointestinal P-Glycoprotein Functional Activity in Response to Etoposide Stimulation. Biol Pharm Bull 2021 1
20 34748768 Spinal CCK contributes to somatic hyperalgesia induced by orofacial inflammation combined with stress in adult female rats. Eur J Pharmacol 2021 Dec 15 2
21 34779255 The hyperthermic effect of central cholecystokinin is mediated by the cyclooxygenase-2 pathway. Am J Physiol Endocrinol Metab 2022 Jan 1 1