methyl 2-(2-acetoxy-6,7-dihydrothieno(3,2-c)pyridin-5(4H)-yl)-2-(2-chlorophenyl)acetate






15 Article(s)
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1 28817486 Overcoming Clopidogrel Resistance: Three Promising Novel Antiplatelet Drugs Developed in China. J Cardiovasc Pharmacol 2017 Dec 1
2 29154109 Development and validation of a sensitive and rapid UHPLC-MS/MS method for the simultaneous quantification of the common active and inactive metabolites of vicagrel and clopidogrel in human plasma. J Pharm Biomed Anal 2018 Feb 5 1
3 29209217 Arylacetamide Deacetylase Is Involved in Vicagrel Bioactivation in Humans. Front Pharmacol 2017 10
4 29973877 Evaluation of Tolerability, Pharmacokinetics and Pharmacodynamics of Vicagrel, a Novel P2Y12 Antagonist, in Healthy Chinese Volunteers. Front Pharmacol 2018 2
5 30326264 Pharmacokinetics and pharmacokinetic/pharmacodynamic relationship of vicagrel, a novel thienopyridine P2Y<sub>12</sub> inhibitor, compared with clopidogrel in healthy Chinese subjects following single oral dosing. Eur J Pharm Sci 2019 Jan 15 4
6 30358688 Aspirin Attenuates the Bioactivation of and Platelet Response to Vicagrel in Mice. J Cardiovasc Pharmacol 2018 Nov 1
7 30825385 Enhanced responsiveness of platelets to vicagrel in IL-10-deficient mice through STAT3-dependent up-regulation of the hydrolase arylacetamide deacetylase in the intestine. Br J Pharmacol 2019 Jun 11
8 31060007 Vicagrel enhances aspirin-induced inhibition of both platelet aggregation and thrombus formation in rodents due to its decreased metabolic inactivation. Biomed Pharmacother 2019 Jul 3
9 31977858 Platelet inhibitory activity, tolerability, and safety of vicagrel, a novel thienopyridine P2Y12 inhibitor. Medicine (Baltimore) 2020 Jan 1
10 32267573 Impacts of CYP2C19 genetic polymorphisms on bioavailability and effect on platelet adhesion of vicagrel, a novel thienopyridine P2Y<sub>12</sub> inhibitor. Br J Clin Pharmacol 2020 Sep 4
11 33244163 Pharmacokinetics, mass balance, and metabolism of [<sup>14</sup>C]vicagrel, a novel irreversible P2Y<sub>12</sub> inhibitor in humans. Acta Pharmacol Sin 2021 Sep 1
12 33424602 Predicting the Effects of CYP2C19 and Carboxylesterases on Vicagrel, a Novel P2Y12 Antagonist, by Physiologically Based Pharmacokinetic/Pharmacodynamic Modeling Approach. Front Pharmacol 2020 12
13 33935793 Corrigendum: Predicting the Effects of CYP2C19 and Carboxylesterases on Vicagrel, a Novel P2Y12 Antagonist, by Physiologically Based Pharmacokinetic/Pharmacodynamic Modeling Approach. Front Pharmacol 2021 2
14 34910929 Inhibition of cytochrome P450 enzymes and uridine 5'-diphospho-glucuronosyltransferases by vicagrel in human liver microsomes: A prediction of potential drug-drug interactions. Chem Biol Interact 2022 Jan 25 16
15 35438151 Antiplatelet effect, safety, and pharmacokinetics of vicagrel in patients with coronary artery disease undergoing percutaneous coronary intervention. Eur Heart J Cardiovasc Pharmacother 2022 Apr 19 1