| 1 | 12497584 | Effects of bufalin and cinobufagin on the proliferation of androgen dependent and independent prostate cancer cells. | Prostate | 2003 Feb 1 |
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| 2 | 15494417 | Cardiotonic steroids differentially affect intracellular Na+ and [Na+]i/[K+]i-independent signaling in C7-MDCK cells. | J Biol Chem | 2005 Jan 7 |
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| 3 | 19037992 | Apoptotic signaling in bufalin- and cinobufagin-treated androgen-dependent and -independent human prostate cancer cells. | Cancer Sci | 2008 Dec |
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| 4 | 20073224 | [Effect of cinobufagin on the expressions of bcl-2 mRNA and bax mRNA and the proliferation of lens epithelial cells]. | Zhongguo Zhong Xi Yi Jie He Za Zhi | 2009 Oct |
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| 5 | 20118004 | [Effect of cinobufagin on nuclear factor-kappaB pathway in HepG2 cells]. | Nan Fang Yi Ke Da Xue Xue Bao | 2010 Jan |
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| 6 | 21215801 | Cardiotonic steroids attenuate ERK phosphorylation and generate cell cycle arrest to block human hepatoma cell growth. | J Steroid Biochem Mol Biol | 2011 Jul |
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| 7 | 21288283 | Bufalin and cinobufagin induce apoptosis of human hepatocellular carcinoma cells via Fas- and mitochondria-mediated pathways. | Cancer Sci | 2011 May |
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| 8 | 21472305 | Apoptosis-inducing activity of compounds screened and characterized from cinobufacini by bioassay-guided isolation. | Mol Med Rep | 2010 Jul-Aug |
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| 9 | 21534035 | Immunomodulatory effects of cinobufagin isolated from Chan Su on activation and cytokines secretion of immunocyte in vitro. | J Asian Nat Prod Res | 2011 May |
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| 10 | 21913902 | Inhibitory effect of bufalin and cinobufagin on steroidogenesis via the activation of ERK in human adrenocortical cells. | Br J Pharmacol | 2012 Mar |
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| 11 | 22178124 | Induction of cytochrome P450 3A by Shexiang Baoxin Pill and its main components. | Chem Biol Interact | 2012 Jan 25 |
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| 12 | 23164673 | The glycogen synthase kinase-3β/nuclear factor-kappa B pathway is involved in cinobufagin-induced apoptosis in cultured osteosarcoma cells. | Toxicol Lett | 2013 Apr 12 |
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| 13 | 24187573 | A Study on the Mechanism of Cinobufagin in the Treatment of Paw Cancer Pain by Modulating Local β -Endorphin Expression In Vivo. | Evid Based Complement Alternat Med | 2013 |
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| 14 | 24844018 | [Effects of cinobufagin on apoptosis in U-2OS osteosarcomas cells]. | Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi | 2014 Mar |
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| 15 | 25982794 | Cinobufagin exerts anti-proliferative and pro-apoptotic effects through the modulation ROS-mediated MAPKs signaling pathway. | Immunopharmacol Immunotoxicol | 2015 Jun |
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| 16 | 26664411 | Immunomodulatory Effects of Cinobufagin on Murine Lymphocytes and Macrophages. | Evid Based Complement Alternat Med | 2015 |
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| 17 | 26959116 | Cinobufagin inhibits tumor growth by inducing intrinsic apoptosis through AKT signaling pathway in human nonsmall cell lung cancer cells. | Oncotarget | 2016 May 17 |
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| 18 | 27176794 | Cinobufagin induces autophagy-mediated cell death in human osteosarcoma U2OS cells through the ROS/JNK/p38 signaling pathway. | Oncol Rep | 2016 Jul |
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| 19 | 27529866 | Cinobufagin Modulates Human Innate Immune Responses and Triggers Antibacterial Activity. | PLoS One | 2016 |
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| 20 | 27574776 | Cinobufagin enhances the protective efficacy of formalin-inactivated Salmonella typhimurium vaccine through Th1 immune response. | Microb Pathog | 2016 Oct |
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| 21 | 27845066 | Cinobufagin induces apoptosis of osteosarcoma cells through inactivation of Notch signaling. | Eur J Pharmacol | 2017 Jan 5 |
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| 22 | 27894091 | Preclinical study of cinobufagin as a promising anti-colorectal cancer agent. | Oncotarget | 2017 Jan 3 |
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| 23 | 28002791 | Chinese herb cinobufagin-reduced cancer pain is associated with increased peripheral opioids by invaded CD3/4/8 lymphocytes. | Oncotarget | 2017 Feb 14 |
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| 24 | 28184922 | Reversal of P-gp-mediated multidrug resistance in colon cancer by cinobufagin. | Oncol Rep | 2017 Mar |
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| 25 | 28412840 | Anti-proliferative and pro-apoptotic effects of cinobufagin on human breast cancer MCF-7 cells and its molecular mechanism. | Nat Prod Res | 2018 Feb |
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| 26 | 29359345 | Simultaneous identification of the anaphylactoid components from traditional Chinese medicine injections using rat basophilic leukemia 2H3 and laboratory of allergic disease 2 dual-mixed/cell membrane chromatography model. | Electrophoresis | 2018 May |
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| 27 | 29669353 | Cinobufagin Induces Apoptosis in Osteosarcoma Cells Via the Mitochondria-Mediated Apoptotic Pathway. | Cell Physiol Biochem | 2018 |
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| 28 | 30247877 | Alpha-7 Nicotinic Receptor-Targeted Cinobufagin Induces Antinociception and Inhibits NF-κB Signaling Pathway in DRG Neurons. | ACS Chem Neurosci | 2019 Jan 16 |
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| 29 | 30839155 | Cinobufagin suppresses colorectal cancer angiogenesis by disrupting the endothelial mammalian target of rapamycin/hypoxia-inducible factor 1α axis. | Cancer Sci | 2019 May |
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| 30 | 30942456 | The anticancer effects of cinobufagin on hepatocellular carcinoma Huh‑7 cells are associated with activation of the p73 signaling pathway. | Mol Med Rep | 2019 May |
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| 31 | 31091577 | [Study on analgesic effect and mechanism of cinobufagin on rats with bone cancer pain]. | Zhonghua Yi Xue Za Zhi | 2019 May 7 |
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| 32 | 31301417 | WITHDRAWN: Cinobufagin induced cell apoptosis and protective autophagy through the ROS/MAPK signaling pathway. | Life Sci | 2019 Jul 11 |
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| 33 | 31474710 | Cinobufagin Promotes Cell Cycle Arrest and Apoptosis to Block Human Esophageal Squamous Cell Carcinoma Cells Growth via the p73 Signalling Pathway. | Biol Pharm Bull | 2019 |
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| 34 | 31552178 | Cinobufagin Induces Cell Cycle Arrest at the G2/M Phase and Promotes Apoptosis in Malignant Melanoma Cells. | Front Oncol | 2019 |
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| 35 | 31572194 | Antifibrotic Mechanism of Cinobufagin in Bleomycin-Induced Pulmonary Fibrosis in Mice. | Front Pharmacol | 2019 |
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| 36 | 31824138 | Cinobufagin Suppresses The Characteristics Of Osteosarcoma Cancer Cells By Inhibiting The IL-6-OPN-STAT3 Pathway. | Drug Des Devel Ther | 2019 |
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| 37 | 31918288 | Cinobufagin induces cell cycle arrest at the S phase and promotes apoptosis in nasopharyngeal carcinoma cells. | Biomed Pharmacother | 2020 Feb |
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| 38 | 32113469 | The spinal microglial IL-10/β-endorphin pathway accounts for cinobufagin-induced mechanical antiallodynia in bone cancer pain following activation of α7-nicotinic acetylcholine receptors. | J Neuroinflammation | 2020 Feb 29 |
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| 39 | 32349518 | Cinobufagin Triggers Defects in Spindle Formation and Cap-Dependent Translation in Liver Cancer Cells by Inhibiting the AURKA-mTOR-eIF4E Axis. | Am J Chin Med | 2020 |
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| 40 | 32933177 | Cinobufagin Suppresses Melanoma Cell Growth by Inhibiting LEF1. | Int J Mol Sci | 2020 Sep 13 |
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| 41 | 33520369 | Cinobufagin suppresses colorectal cancer growth via STAT3 pathway inhibition. | Am J Cancer Res | 2021 |
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| 42 | 34619160 | A network pharmacology approach to investigate the anticancer mechanism of cinobufagin against hepatocellular carcinoma via downregulation of EGFR-CDK2 signaling. | Toxicol Appl Pharmacol | 2021 Nov 15 |
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| 43 | 34737550 | Cinobufagin Suppresses the Characteristics of Osteosarcoma Cancer Cells by Inhibiting the IL-6-OPN-STAT3 Pathway [Retraction]. | Drug Des Devel Ther | 2021 |
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| 44 | 34740818 | Small molecule targeting topoisomerase 3β for cancer therapy. | Pharmacol Res | 2021 Dec |
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| 45 | 34769467 | Cinobufagin Exerts Anticancer Activity in Oral Squamous Cell Carcinoma Cells through Downregulation of ANO1. | Int J Mol Sci | 2021 Nov 7 |
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| 46 | 34925034 | Cinobufagin Is a Selective Anti-Cancer Agent against Tumors with EGFR Amplification and PTEN Deletion. | Front Pharmacol | 2021 |
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| 47 | 35114328 | Chemically synthesized cinobufagin suppresses nasopharyngeal carcinoma metastasis by inducing ENKUR to stabilize p53 expression. | Cancer Lett | 2022 Apr 10 |
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| 48 | 35176466 | Cinobufagin induces FOXO1-regulated apoptosis, proliferation, migration, and invasion by inhibiting G9a in non-small-cell lung cancer A549 cells. | J Ethnopharmacol | 2022 Jun 12 |
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| 49 | 35427566 | Cinobufagin restrains the growth and triggers DNA damage of human hepatocellular carcinoma cells via proteasome-dependent degradation of thymidylate synthase. | Chem Biol Interact | 2022 Jun 1 |
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