exemestane






229 Article(s)
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1 1394219 Phase I and endocrine study of exemestane (FCE 24304), a new aromatase inhibitor, in postmenopausal women. Cancer Res 1992 Nov 1 1
2 8273115 Synthesis and aromatase inhibition by potential metabolites of exemestane (6-methylenandrosta-1,4-diene-3,17-dione). Steroids 1993 Nov 1
3 11250604 [Preclinical evaluation of aromatase inhibitors antitumor activity]. Bull Cancer 2000 Dec 1
4 11550075 Aromatase, aromatase inhibitors, and breast cancer. Am J Ther 2001 Sep-Oct 2
5 11850211 Comparative clinical pharmacology and pharmacokinetic interactions of aromatase inhibitors. J Steroid Biochem Mol Biol 2001 Dec 2
6 11916226 Are differences in the available aromatase inhibitors and inactivators significant? Clin Cancer Res 2001 Dec 4
7 12113240 Aromatase inhibitors in breast cancer therapy. Expert Rev Anticancer Ther 2002 Apr 2
8 12402060 The evolving role of aromatase inhibitors in breast cancer. Int J Clin Oncol 2002 Oct 4
9 12455303 Exemestane: treatment of breast cancer with selective inactivation of aromatase. Am J Health Syst Pharm 2002 Nov 15 1
10 12684675 Could exemestane affect insulin-like growth factors, interleukin 6 and bone metabolism in postmenopausal advanced breast cancer patients after failure on aminoglutethimide, anastrozole or letrozole? Int J Oncol 2003 May 1
11 12722879 Aromatase inhibitors for treatment of postmenopausal patients with breast cancer. Expert Rev Anticancer Ther 2003 Apr 2
12 14513436 Aromatase inhibitors in early breast cancer treatment. Semin Oncol 2003 Aug 1
13 14623539 An integrated view of aromatase and its inhibition. J Steroid Biochem Mol Biol 2003 Sep 1
14 15083379 Aromatase inhibitors: new endocrine treatment of breast cancer. Semin Reprod Med 2004 Feb 2
15 15125996 A human and mouse pregnane X receptor reporter gene assay in combination with cytotoxicity measurements as a tool to evaluate species-specific CYP3A induction. Toxicology 2004 Jun 1 1
16 15150604 Aromatase inhibition in the treatment of advanced breast cancer: is there a relationship between potency and clinical efficacy? Br J Cancer 2004 May 4 1
17 15358790 Biochemical and biological characterization of a novel anti-aromatase coumarin derivative. J Biol Chem 2004 Nov 12 2
18 15476902 Role of aromatase inhibitors in the treatment of breast cancer. Clin Ther 2004 Aug 1
19 15719595 Aromatase inhibitors in advanced breast cancer. Semin Oncol 2004 Dec 1
20 15719596 Aromatase inhibitors in early breast cancer therapy. Semin Oncol 2004 Dec 1
21 15723135 Expression of estrogen receptors-alpha and -beta in primary breast neoplasms and tumors exposed to neoadjuvant hormonal therapy. Bull Exp Biol Med 2004 Nov 1
22 15748828 Aromatase expression in ovarian epithelial cancers. J Steroid Biochem Mol Biol 2005 Jan 2
23 15814851 Aromatase inhibitors in the treatment of breast cancer. Endocr Rev 2005 May 1
24 15909811 [Comparison of letrozole and exemestane used in non-adjuvant therapy of endometrial carcinoma]. Vopr Onkol 2005 1
25 16054421 New approaches to reverse resistance to hormonal therapy in human breast cancer. Drug Resist Updat 2005 Aug 1
26 16322257 Human aromatase: gene resequencing and functional genomics. Cancer Res 2005 Dec 1 1
27 16904960 Changes in bone turnover and in bone mass in women with breast cancer switched from tamoxifen to exemestane. Bone 2007 Jan 1
28 16950593 Metastatic breast cancer: an updating. Biomed Pharmacother 2006 Nov 1
29 17066438 5Alpha-reductase type 1 and aromatase in breast carcinoma as regulators of in situ androgen production. Int J Cancer 2007 Jan 15 2
30 17079446 Aromatase destabilizer: novel action of exemestane, a food and drug administration-approved aromatase inhibitor. Cancer Res 2006 Nov 1 8
31 17150002 Aromatase inhibitors in early breast cancer therapy: a variety of treatment strategies. Expert Opin Pharmacother 2006 Dec 1
32 17695434 Exemestane as neoadjuvant hormonotherapy for locally advanced breast cancer: results of a phase II trial. Anticancer Res 2007 Jul-Aug 2
33 17904790 Aromatase inhibitor and bone. Biomed Pharmacother 2007 Oct 1
34 17989318 Exemestane's 17-hydroxylated metabolite exerts biological effects as an androgen. Mol Cancer Ther 2007 Nov 2
35 18043897 Multicenter phase II trial of neoadjuvant exemestane for postmenopausal patients with hormone receptor-positive, operable breast cancer: Saitama Breast Cancer Clinical Study Group (SBCCSG-03). Breast Cancer Res Treat 2008 Jan 3
36 18158620 Exemestane as primary systemic treatment for hormone receptor positive post-menopausal breast cancer patients: a phase II trial of the Austrian Breast and Colorectal Cancer Study Group (ABCSG-17). Breast Cancer Res Treat 2008 Nov 3
37 18194278 NSAIDs and breast cancer: a possible prevention and treatment strategy. Int J Clin Pract 2008 Mar 1
38 18256205 CYP1B1 is not a major determinant of the disposition of aromatase inhibitors in epithelial cells of invasive ductal carcinoma. Drug Metab Dispos 2008 May 1
39 18282367 Managing bone loss in women with early-stage breast cancer receiving aromatase inhibitors. Clin Breast Cancer 2007 Dec 1
40 18367396 Aromatase inhibitors in early breast-cancer treatment: The story so far. Breast 2008 Apr 1
41 18381432 The role of amphiregulin in exemestane-resistant breast cancer cells: evidence of an autocrine loop. Cancer Res 2008 Apr 1 10
42 18473177 Exemestane loaded self-microemulsifying drug delivery system (SMEDDS): development and optimization. AAPS PharmSciTech 2008 1
43 18490163 Reducing early recurrence with adjuvant aromatase inhibitors: what is the evidence? Breast 2008 Aug 1
44 18677558 Characterization of the weak estrogen receptor alpha agonistic activity of exemestane. Breast Cancer Res Treat 2009 Aug 1
45 19046724 The effects on lipid serum levels of a 2-year adjuvant treatment with exemestane after tamoxifen in postmenopausal women with early breast cancer. Eur J Intern Med 2008 Dec 2
46 19250201 Phase 3 trials of aromatase inhibitors for breast cancer prevention: following in the path of the selective estrogen receptor modulators. Ann N Y Acad Sci 2009 Feb 2
47 19281057 Aromatase inhibitors, efficacy and metabolic risk in the treatment of postmenopausal women with early breast cancer. Clin Interv Aging 2008 1
48 19659610 Predictors of response to exemestane as primary endocrine therapy in estrogen receptor-positive breast cancer. Cancer Sci 2009 Nov 3
49 19661043 Visual impairment in myopic patients with breast cancer receiving adjuvant therapy with aromatase inhibitors. Clin Breast Cancer 2009 Aug 1
50 19670731 [Criteria for evaluating the effectiveness of aromatase inhibitors in the neoadjuvant treatment of patients with endometrial carcinoma]. Vopr Onkol 2009 1