Oxaliplatin






1814 Article(s)
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1 1316878 Leukotriene B4 omega-oxidation by human polymorphonuclear leukocytes is inhibited by pyocyanin, a phenazine derivative produced by Pseudomonas aeruginosa. Infect Immun 1992 Jun 2
2 7763011 Evaluation of novel platinum complexes, inhibitors of topoisomerase I and II in non-small cell lung cancer (NSCLC) sublines resistant to cisplatin. Anticancer Res 1995 Mar-Apr 1
3 8689632 Altered glutathione metabolism in oxaliplatin resistant ovarian carcinoma cells. Cancer Lett 1996 Jul 19 1
4 8895738 The role of DNA mismatch repair in platinum drug resistance. Cancer Res 1996 Nov 1 1
5 9114434 Induction of gamma-glutamyl transpeptidase mRNA by platinum complexes in a human ovarian carcinoma cell line. Oncol Res 1996 6
6 9220289 Comparative cytotoxicity of oxaliplatin and cisplatin in non-seminomatous germ cell cancer cell lines. Invest New Drugs 1997 1
7 9488590 Urinary excretion of 1-hydroxypyrene as a marker for exposure to urban air levels of polycyclic aromatic hydrocarbons. Cancer Epidemiol Biomarkers Prev 1998 Feb 2
8 9721864 The role of hMLH1, hMSH3, and hMSH6 defects in cisplatin and oxaliplatin resistance: correlation with replicative bypass of platinum-DNA adducts. Cancer Res 1998 Aug 15 2
9 9752993 Cytochrome P450 1A1 MspI polymorphism and urinary 1-hydroxypyrene concentrations in coke-oven workers. Cancer Epidemiol Biomarkers Prev 1998 Sep 1
10 9804612 Sequence- and region-specificity of oxaliplatin adducts in naked and cellular DNA. Mol Pharmacol 1998 Nov 3
11 9804920 Cytogenetic biomonitoring of workers exposed to bitumen fumes. Mutat Res 1998 Nov 9 1
12 10098743 Induction of JNK and c-Abl signalling by cisplatin and oxaliplatin in mismatch repair-proficient and -deficient cells. Br J Cancer 1999 Mar 2
13 10098901 Biotransformations of oxaliplatin in rat blood in vitro. J Biochem Mol Toxicol 1999 1
14 10367745 Pharmacokinetics and biotransformations of oxaliplatin in comparison with ormaplatin following a single bolus intravenous injection in rats. Cancer Chemother Pharmacol 1999 1
15 10460158 Effect of DNA polymerases and high mobility group protein 1 on the carrier ligand specificity for translesion synthesis past platinum-DNA adducts. Biochemistry 1999 Aug 24 2
16 10511262 Urinary 1-hydroxypyrene and other PAH metabolites as biomarkers of exposure to environmental PAH in air particulate matter. Toxicol Lett 1999 Sep 5 3
17 10606258 Oxaliplatin: a new therapeutic option in colorectal cancer. Semin Oncol 1999 Dec 1
18 10626357 Specificity of platinum-DNA adduct repair. J Inorg Biochem 1999 Oct 2
19 10650914 The influence of cytochrome P450 1A1 and glutathione S-transferase M1 genotypes on biomarker levels in coke-oven workers. Arch Toxicol 1999 Nov 1
20 10753202 CYP1A1 and GSTM1 polymorphisms affect urinary 1-hydroxypyrene levels after PAH exposure. Carcinogenesis 2000 Apr 2
21 10769112 Efficient translesion replication past oxaliplatin and cisplatin GpG adducts by human DNA polymerase eta. Biochemistry 2000 Apr 25 2
22 10777605 The efficiency and fidelity of translesion synthesis past cisplatin and oxaliplatin GpG adducts by human DNA polymerase beta. J Biol Chem 2000 Apr 28 3
23 11053984 Oxaliplatin-induced fever and release of IL-6. Oncology 2000 Sep 3
24 11142694 Oxaliplatin is active in vitro against human melanoma cell lines: comparison with cisplatin and carboplatin. Anticancer Drugs 2000 Nov 1
25 11167991 Influence of cytokines, monoclonal antibodies and chemotherapeutic drugs on epithelial cell adhesion molecule (EpCAM) and LewisY antigen expression. Clin Exp Immunol 2001 Jan 1
26 11323399 Effects of occupation, lifestyle and genetic polymorphisms of CYP1A1, CYP2E1, GSTM1 and GSTT1 on urinary 1-hydroxypyrene and 2-naphthol concentrations. Carcinogenesis 2001 May 3
27 11583787 Comparison of the binding behavior of oxaliplatin, cisplatin and analogues to 5'-GMP in the presence of sulfur-containing molecules by means of capillary electrophoresis and electrospray mass spectrometry. J Inorg Biochem 2001 Oct 1
28 11593056 Combination of oxaliplatin and irinotecan on human colon cancer cell lines: activity in vitro and in vivo. Anticancer Drugs 2001 Oct 1
29 11600727 Urinary 1-hydroxypyrene in coke oven workers relative to exposure, alcohol consumption, and metabolic enzymes. Occup Environ Med 2001 Nov 4
30 11705873 Characterization of a thymidylate synthase (TS)-inducible cell line: a model system for studying sensitivity to TS- and non-TS-targeted chemotherapies. Clin Cancer Res 2001 Nov 1
31 11712813 A polymorphism of the XRCC1 gene predicts for response to platinum based treatment in advanced colorectal cancer. Anticancer Res 2001 Jul-Aug 1
32 11731512 ERCC1 and thymidylate synthase mRNA levels predict survival for colorectal cancer patients receiving combination oxaliplatin and fluorouracil chemotherapy. J Clin Oncol 2001 Dec 1 3
33 11824623 Application of capillary electrophoresis-mass spectrometry for the investigation of the binding behavior of oxaliplatin to 5'-GMP in the presence of the sulfur-containing amino acid L-methionine. Electrophoresis 2002 Jan 7
34 11859435 The effect of relevant genotypes on PAH exposure-related biomarkers. J Expo Anal Environ Epidemiol 2002 Jan-Feb 1
35 11919232 Phase II study of capecitabine and oxaliplatin in first- and second-line treatment of advanced or metastatic colorectal cancer. J Clin Oncol 2002 Apr 1 1
36 11953866 Impact of the oxaliplatin-5 fluorouracil-folinic acid combination on respective intracellular determinants of drug activity. Br J Cancer 2002 Apr 8 1
37 11958906 Radiosensitization by oxaliplatin in a mouse adenocarcinoma: influence of treatment schedule. Int J Radiat Oncol Biol Phys 2002 Mar 15 1
38 12008204 Oxaliplatin (L-OHP) treatment of human myeloma cells induces in vitro growth inhibition and apoptotic cell death. Eur J Cancer 2002 May 2
39 12072547 Association between glutathione S-transferase P1, T1, and M1 genetic polymorphism and survival of patients with metastatic colorectal cancer. J Natl Cancer Inst 2002 Jun 19 2
40 12144121 Oxaliplatin may induce cytokine-release syndrome in colorectal cancer patients. J Biol Regul Homeost Agents 2002 Apr-Jun 2
41 12372606 Drug specific resistance to oxaliplatin is associated with apoptosis defect in a cellular model of colon carcinoma. FEBS Lett 2002 Oct 9 1
42 12391279 The copper transporter CTR1 regulates cisplatin uptake in Saccharomyces cerevisiae. Mol Pharmacol 2002 Nov 1
43 12434296 Increased sensitivity of p53-deficient cells to anticancer agents due to loss of Pms2. Br J Cancer 2002 Oct 21 1
44 12441268 Retention of activity by the new generation platinum agent AMD0473 in four human tumour cell lines possessing acquired resistance to oxaliplatin. Eur J Cancer 2002 Nov 1
45 12499281 Chemoradiation of cervical cancer cells: targeting human papillomavirus E6 and p53 leads to either augmented or attenuated apoptosis depending on the platinum carrier ligand. Cancer Res 2002 Dec 15 2
46 12504667 Cellular determinants of oxaliplatin sensitivity in colon cancer cell lines. Eur J Cancer 2003 Jan 6
47 12531010 Frameshifts and deletions during in vitro translesion synthesis past Pt-DNA adducts by DNA polymerases beta and eta. DNA Repair (Amst) 2002 Dec 5 7
48 12553056 Circulating nerve growth factor level changes during oxaliplatin treatment-induced neurotoxicity in the rat. Anticancer Res 2002 Nov-Dec 3
49 12570658 Mechanisms controlling sensitivity to platinum complexes: role of p53 and DNA mismatch repair. Curr Cancer Drug Targets 2003 Feb 1
50 12578393 Translesion synthesis past platinum DNA adducts by human DNA polymerase mu. Biochemistry 2003 Feb 18 1