| 1 | 11435459 | c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis. | J Clin Invest | 2001 Jul |
6 |
| 2 | 11717429 | SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase. | Proc Natl Acad Sci U S A | 2001 Nov 20 |
9 |
| 3 | 12031798 | An inhibitor of c-jun aminoterminal kinase (SP600125) represses c-Jun activation, DNA-binding and PMA-inducible 92-kDa type IV collagenase expression. | Biochim Biophys Acta | 2002 May 8 |
11 |
| 4 | 12169099 | Up-regulation of c-jun mRNA in cardiac myocytes requires the extracellular signal-regulated kinase cascade, but c-Jun N-terminal kinases are required for efficient up-regulation of c-Jun protein. | Biochem J | 2002 Nov 15 |
7 |
| 5 | 12176045 | Heat shock response inhibits IL-18 expression through the JNK pathway in murine peritoneal macrophages. | Biochem Biophys Res Commun | 2002 Aug 23 |
2 |
| 6 | 12220537 | Activation of the mitochondrial caspase cascade in the absence of protein synthesis does not require c-Jun N-terminal kinase. | Arch Biochem Biophys | 2002 Sep 15 |
3 |
| 7 | 12221076 | Nocodazole-induced p53-dependent c-Jun N-terminal kinase activation reduces apoptosis in human colon carcinoma HCT116 cells. | J Biol Chem | 2002 Nov 15 |
5 |
| 8 | 12368275 | Characterization of signaling pathways activated by the interleukin 1 (IL-1) receptor homologue T1/ST2. A role for Jun N-terminal kinase in IL-4 induction. | J Biol Chem | 2002 Dec 20 |
3 |
| 9 | 12397601 | Stress-activated protein kinase/c-Jun N-terminal kinase (JNK) plays a part in endothelin-1-induced vascular endothelial growth factor synthesis in osteoblasts. | J Cell Biochem | 2002 |
7 |
| 10 | 12409308 | Salicylic acid reverses phorbol 12-myristate-13-acetate (PMA)- and tumor necrosis factor alpha (TNFalpha)-induced insulin receptor substrate 1 (IRS1) serine 307 phosphorylation and insulin resistance in human embryonic kidney 293 (HEK293) cells. | J Biol Chem | 2003 Jan 3 |
6 |
| 11 | 12421945 | Differential regulation of CD44 expression by lipopolysaccharide (LPS) and TNF-alpha in human monocytic cells: distinct involvement of c-Jun N-terminal kinase in LPS-induced CD44 expression. | J Immunol | 2002 Nov 15 |
1 |
| 12 | 12502846 | The herpes simplex virus type 2 R1 protein kinase (ICP10 PK) functions as a dominant regulator of apoptosis in hippocampal neurons involving activation of the ERK survival pathway and upregulation of the antiapoptotic protein Bag-1. | J Virol | 2003 Jan |
4 |
| 13 | 12509925 | [Synergetic effect of mitogen-activated protein kinase pathway on expression of tumor necrosis factor alpha gene in RAW 264.7 cells induced by lipopolysaccharide]. | Zhonghua Yi Xue Za Zhi | 2002 Oct 25 |
2 |
| 14 | 12510059 | Modulation of insulin-stimulated degradation of human insulin receptor substrate-1 by Serine 312 phosphorylation. | J Biol Chem | 2003 Mar 7 |
1 |
| 15 | 12527812 | Critical role of c-Jun N-terminal protein kinase activation in troglitazone-induced apoptosis of human HepG2 hepatoma cells. | Mol Pharmacol | 2003 Feb |
9 |
| 16 | 12562529 | Involvement of c-Jun N-terminal kinase in amyloid precursor protein-mediated neuronal cell death. | J Neurochem | 2003 Feb |
1 |
| 17 | 12574140 | Beta-adrenergic receptor-stimulated apoptosis in cardiac myocytes is mediated by reactive oxygen species/c-Jun NH2-terminal kinase-dependent activation of the mitochondrial pathway. | Circ Res | 2003 Feb 7 |
1 |
| 18 | 12587073 | Herpes simplex virus type 1-induced encephalitis has an apoptotic component associated with activation of c-Jun N-terminal kinase. | J Neurovirol | 2003 Feb |
2 |
| 19 | 12589827 | Amphiregulin is a potent mitogen for the vascular smooth muscle cell line, A7r5. | Biochem Biophys Res Commun | 2003 Feb 21 |
1 |
| 20 | 12600999 | Hypertonicity-induced aquaporin-1 (AQP1) expression is mediated by the activation of MAPK pathways and hypertonicity-responsive element in the AQP1 gene. | J Biol Chem | 2003 May 2 |
5 |
| 21 | 12603281 | Inhibition of hippocampal Jun N-terminal kinase enhances short-term memory but blocks long-term memory formation and retrieval of an inhibitory avoidance task. | Eur J Neurosci | 2003 Feb |
2 |
| 22 | 12618755 | Grape seed extract inhibits EGF-induced and constitutively active mitogenic signaling but activates JNK in human prostate carcinoma DU145 cells: possible role in antiproliferation and apoptosis. | Oncogene | 2003 Mar 6 |
3 |
| 23 | 12637567 | Transcriptional regulation of heme oxygenase-1 gene expression by MAP kinases of the JNK and p38 pathways in primary cultures of rat hepatocytes. | J Biol Chem | 2003 May 16 |
3 |
| 24 | 12642693 | Coadministration of UCN-01 with MEK1/2 inhibitors potently induces apoptosis in BCR/ABL+ leukemia cells sensitive and resistant to ST1571. | Cancer Biol Ther | 2002 Nov-Dec |
4 |
| 25 | 12644304 | Type 2 deiodinase expression is stimulated by growth factors in human vascular smooth muscle cells. | Mol Cell Endocrinol | 2003 Feb 28 |
3 |
| 26 | 12654505 | Activation of mitogen-activated protein kinase pathways during the death of PC12 cells is dependent on the state of differentiation. | Brain Res Mol Brain Res | 2003 Mar 17 |
3 |
| 27 | 12663670 | The activation of c-Jun NH2-terminal kinase (JNK) by DNA-damaging agents serves to promote drug resistance via activating transcription factor 2 (ATF2)-dependent enhanced DNA repair. | J Biol Chem | 2003 Jun 6 |
2 |
| 28 | 12665525 | JNK-dependent release of mitochondrial protein, Smac, during apoptosis in multiple myeloma (MM) cells. | J Biol Chem | 2003 May 16 |
2 |
| 29 | 12668975 | c-Jun-N-terminal kinase drives cyclin D1 expression and proliferation during liver regeneration. | Hepatology | 2003 Apr |
11 |
| 30 | 12681294 | JNK1 activity lowers the cellular production of H2O2 and modulates the growth arrest response to scavenging of H2O2 by catalase. | Exp Cell Res | 2003 Apr 15 |
2 |
| 31 | 12697041 | Involvement of SAPK/JNK in basic fibroblast growth factor-induced vascular endothelial growth factor release in osteoblasts. | J Endocrinol | 2003 Apr |
5 |
| 32 | 12699771 | A role for c-Jun N-terminal kinase in the inhibition of long-term potentiation by interleukin-1beta and long-term depression in the rat dentate gyrus in vitro. | Neuroscience | 2003 |
4 |
| 33 | 12704792 | ERK, JNK, and p38 MAP kinases differentially regulate proliferation and migration of phenotypically distinct smooth muscle cell subtypes. | J Cell Biochem | 2003 May 15 |
3 |
| 34 | 12709432 | Ephrin-B1 reverse signaling activates JNK through a novel mechanism that is independent of tyrosine phosphorylation. | J Biol Chem | 2003 Jul 4 |
3 |
| 35 | 12714616 | Defensin expression by the cornea: multiple signalling pathways mediate IL-1beta stimulation of hBD-2 expression by human corneal epithelial cells. | Invest Ophthalmol Vis Sci | 2003 May |
3 |
| 36 | 12716652 | Stretch-induced IL-8 depends on c-Jun NH2-terminal and nuclear factor-kappaB-inducing kinases. | Am J Physiol Lung Cell Mol Physiol | 2003 Aug |
1 |
| 37 | 12717136 | Midazolam stimulates vascular endothelial growth factor release in aortic smooth muscle cells: role of the mitogen-activated protein kinase superfamily. | Anesthesiology | 2003 May |
2 |
| 38 | 12717385 | Toll-like receptor 4 mediates inflammatory signaling by bacterial lipopolysaccharide in human hepatic stellate cells. | Hepatology | 2003 May |
2 |
| 39 | 12730213 | Disruption of basal JNK activity differentially affects key fibroblast functions important for wound healing. | J Biol Chem | 2003 Jul 4 |
1 |
| 40 | 12730216 | Neurotoxic mechanisms caused by the Alzheimer's disease-linked Swedish amyloid precursor protein mutation: oxidative stress, caspases, and the JNK pathway. | J Biol Chem | 2003 Jul 25 |
3 |
| 41 | 12759338 | Activation of c-Jun-N-terminal-kinase is crucial for the induction of a cell cycle arrest in human colon carcinoma cells caused by flurbiprofen enantiomers. | FASEB J | 2003 Jul |
3 |
| 42 | 12819185 | The roles of JNK and apoptotic signaling pathways in PEITC-mediated responses in human HT-29 colon adenocarcinoma cells. | Carcinogenesis | 2003 Aug |
1 |
| 43 | 12829440 | Human hepatic stellate cells express CCR5 and RANTES to induce proliferation and migration. | Am J Physiol Gastrointest Liver Physiol | 2003 Nov |
3 |
| 44 | 12829723 | The cytoplasmic domain of Alzheimer's amyloid-beta protein precursor causes sustained apoptosis signal-regulating kinase 1/c-Jun NH2-terminal kinase-mediated neurotoxic signal via dimerization. | J Pharmacol Exp Ther | 2003 Sep |
2 |
| 45 | 12832416 | Disruption of the c-JUN-JNK complex by a cell-permeable peptide containing the c-JUN delta domain induces apoptosis and affects a distinct set of interleukin-1-induced inflammatory genes. | J Biol Chem | 2003 Oct 10 |
5 |
| 46 | 12842758 | Ligation of IFN-gamma-induced HLA-DR molecules on fibroblasts induces RANTES expression via c-Jun N-terminal kinase (JNK) pathway. | Cytokine | 2003 Jun 7 |
3 |
| 47 | 12842862 | Lipopolysaccharide and proinflammatory cytokines stimulate interleukin-6 expression in C2C12 myoblasts: role of the Jun NH2-terminal kinase. | Am J Physiol Regul Integr Comp Physiol | 2003 Nov |
12 |
| 48 | 12847227 | c-Jun N-terminal kinase negatively regulates lipopolysaccharide-induced IL-12 production in human macrophages: role of mitogen-activated protein kinase in glutathione redox regulation of IL-12 production. | J Immunol | 2003 Jul 15 |
4 |
| 49 | 12858017 | Role of sphingomyelin-MAPKs pathway in heat-induced apoptosis. | Exp Mol Med | 2003 Jun 30 |
1 |
| 50 | 12859962 | Inhibition of arachidonate 5-lipoxygenase triggers prostate cancer cell death through rapid activation of c-Jun N-terminal kinase. | Biochem Biophys Res Commun | 2003 Jul 25 |
2 |