triterpenoids






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1 8328279 [Studies on the triterpenoids from roots of Glycyrrhiza squamulosa Franch]. Yao Xue Xue Bao 1993 1
2 8588874 Selective inhibition of cyclic AMP-dependent protein kinase by amphiphilic triterpenoids and related compounds. Phytochemistry 1996 Jan 7
3 9485026 Novel triterpenoids suppress inducible nitric oxide synthase (iNOS) and inducible cyclooxygenase (COX-2) in mouse macrophages. Cancer Res 1998 Feb 15 8
4 10654412 DNA polymerase beta inhibitors from Baeckea gunniana. J Nat Prod 1999 Dec 1
5 10794703 Novel synthetic oleanane and ursane triterpenoids with various enone functionalities in ring A as inhibitors of nitric oxide production in mouse macrophages. J Med Chem 2000 May 4 1
6 10968284 Pentacyclic triterpenoids from Freziera sp. that inhibit DNA polymerase beta. Bioorg Med Chem 2000 Jan 2
7 10970789 Novel triterpenoids inhibit both DNA polymerase and DNA topoisomerase. Biochem J 2000 Sep 15 1
8 12007601 Novel anti-inflammatory compounds from Rubus sieboldii, triterpenoids, are inhibitors of mammalian DNA polymerases. Biochim Biophys Acta 2002 Apr 29 3
9 12186419 Effects of oleanane-type triterpenoids from fabaceous plants on the expression of ICAM-1. Biol Pharm Bull 2002 Aug 3
10 12367771 Effect of three triterpenoids, lupeol, betulin, and betulinic acid on the stimulus-induced superoxide generation and tyrosyl phosphorylation of proteins in human neutrophils. Clin Chim Acta 2002 Nov 1
11 12649201 Synthetic triterpenoids enhance transforming growth factor beta/Smad signaling. Cancer Res 2003 Mar 15 6
12 12931220 Synthetic triterpenoids activate a pathway for apoptosis in AML cells involving downregulation of FLIP and sensitization to TRAIL. Leukemia 2003 Nov 1
13 12943194 New ursolic and betulinic derivatives as potential cytotoxic agents. J Enzyme Inhib Med Chem 2003 Apr 1
14 15124099 The hemolytic activity of epoxydammarane triterpenoids. Planta Med 2004 May 1
15 15798995 Bioactive triterpenoids from Vochysia pacifica interact with cyclic nucleotide phosphodiesterase isozyme PDE4. Phytother Res 2005 Jan 1
16 15930299 The synthetic triterpenoids, CDDO and CDDO-imidazolide, are potent inducers of heme oxygenase-1 and Nrf2/ARE signaling. Cancer Res 2005 Jun 1 4
17 15930300 Synthetic triterpenoids cooperate with tumor necrosis factor-related apoptosis-inducing ligand to induce apoptosis of breast cancer cells. Cancer Res 2005 Jun 1 3
18 16202612 Tyrosinase inhibitory cycloartane type triterpenoids from the methanol extract of the whole plant of Amberboa ramosa Jafri and their structure-activity relationship. Bioorg Med Chem 2006 Feb 15 2
19 16364033 Phytocomponents of triterpenoids, oleanolic acid and ursolic acid, regulated differently the processing of epidermal keratinocytes via PPAR-alpha pathway. Exp Dermatol 2006 Jan 1
20 16405902 Effect of five triterpenoid compounds isolated from root bark of Aralia elata on stimulus-induced superoxide generation, tyrosyl or serine/threonine phosphorylation and translocation of p47(phox), p67(phox), and rac to cell membrane in human neutrophils. Arch Biochem Biophys 2006 Feb 1 1
21 16435854 A putative precursor of isomalabaricane triterpenoids from lanosterol synthase mutants. Org Lett 2006 Feb 2 1
22 16489057 Potent protection against aflatoxin-induced tumorigenesis through induction of Nrf2-regulated pathways by the triterpenoid 1-[2-cyano-3-,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole. Cancer Res 2006 Feb 15 1
23 16818503 The synthetic triterpenoid CDDO-imidazolide induces monocytic differentiation by activating the Smad and ERK signaling pathways in HL60 leukemia cells. Mol Cancer Ther 2006 Jun 1
24 16830816 [Review of bioactivities of natural cycloartane triterpenoids]. Zhongguo Zhong Yao Za Zhi 2006 Apr 1
25 17136324 Ursane triterpenoids inhibit atherosclerosis and xanthoma in LDL receptor knockout mice. Cardiovasc Drugs Ther 2006 Oct 1
26 17237276 Pharmacodynamic characterization of chemopreventive triterpenoids as exceptionally potent inducers of Nrf2-regulated genes. Mol Cancer Ther 2007 Jan 1
27 17361329 Synthetic triterpenoids inhibit growth and induce apoptosis in human glioblastoma and neuroblastoma cells through inhibition of prosurvival Akt, NF-kappaB and Notch1 signaling. J Neurooncol 2007 Sep 2
28 17503850 Cancer chemopreventive effects of cycloartane-type and related triterpenoids in in vitro and in vivo models. J Nat Prod 2007 Jun 1
29 17711345 Agladupols A-E, triterpenoids from Aglaia duperreana. J Nat Prod 2007 Sep 1
30 17822364 Preclinical evaluation of targeting the Nrf2 pathway by triterpenoids (CDDO-Im and CDDO-Me) for protection from LPS-induced inflammatory response and reactive oxygen species in human peripheral blood mononuclear cells and neutrophils. Antioxid Redox Signal 2007 Nov 1
31 17889544 Natural triterpenoids from Cecropia lyratiloba are cytotoxic to both sensitive and multidrug resistant leukemia cell lines. Bioorg Med Chem 2007 Dec 1 1
32 17917299 Chemical phenotypes of the hmg1 and hmg2 mutants of Arabidopsis demonstrate the in-planta role of HMG-CoA reductase in triterpene biosynthesis. Chem Pharm Bull (Tokyo) 2007 Oct 1
33 18065492 The synthetic oleanane triterpenoid, CDDO-methyl ester, is a potent antiangiogenic agent. Mol Cancer Ther 2007 Dec 1
34 18384989 Anti-inflammatory and analgesic activities of ethanolic extract and two limonoids from Melia toosendan fruit. J Ethnopharmacol 2008 May 22 1
35 18608528 Immunomodulatory activity of synthetic triterpenoids: inhibition of lymphocyte proliferation, cell-mediated cytotoxicity, and cytokine gene expression through suppression of NF-kappaB. Immunopharmacol Immunotoxicol 2008 1
36 18757413 Glycogen synthase kinase 3beta regulates cell death induced by synthetic triterpenoids. Cancer Res 2008 Sep 1 1
37 18822345 11beta-Hydroxysteroid dehydrogenase type 1 inhibitors with oleanan and ursan scaffolds. Mol Cell Endocrinol 2009 Mar 25 1
38 18838692 Coordinate regulation of enzyme markers for inflammation and for protection against oxidants and electrophiles. Proc Natl Acad Sci U S A 2008 Oct 14 2
39 18975157 Suppressive effects of triterpenoids on CINC-1 induction in interleukin-1beta-stimulated rat fibroblast NRK-49F cells. Arch Pharm Res 1997 Jun 2
40 19063958 Identification of Escherichia coli enterotoxin inhibitors from traditional medicinal herbs by in silico, in vitro, and in vivo analyses. J Ethnopharmacol 2009 Jan 30 2
41 19100343 Efficacy and mechanism of action of KHBJ-9B, a new herbal medicine, and its major compound triterpenoids in human cartilage culture and in a rabbit model of collagenase-induced osteoarthritis. Int Immunopharmacol 2009 Feb 8
42 19213570 Anti-angiogenic activity of a novel class of chemopreventive compounds: oleanic acid terpenoids. Recent Results Cancer Res 2009 1
43 19360320 Mechanism of HMGB1 release inhibition from RAW264.7 cells by oleanolic acid in Prunus mume Sieb. et Zucc. Int J Mol Med 2009 May 1
44 19494206 Synthetic triterpenoids attenuate cytotoxic retinal injury: cross-talk between Nrf2 and PI3K/AKT signaling through inhibition of the lipid phosphatase PTEN. Invest Ophthalmol Vis Sci 2009 Nov 3
45 19534474 Sipholane triterpenoids: chemistry, reversal of ABCB1/P-glycoprotein-mediated multidrug resistance, and pharmacophore modeling. J Nat Prod 2009 Jul 2
46 19732782 Targeting NRF2 signaling for cancer chemoprevention. Toxicol Appl Pharmacol 2010 Apr 1 2
47 19846941 Evaluation of cucurbitane-type triterpenoids from Momordica balsamina on P-glycoprotein (ABCB1) by flow cytometry and real-time fluorometry. Anticancer Res 2009 Oct 2
48 19911563 Secondary metabolites from the liverwort Ptilidium pulcherrimum. Nat Prod Commun 2009 Oct 1
49 19911773 Structure-activity relationship study of betulinic acid, a novel and selective TGR5 agonist, and its synthetic derivatives: potential impact in diabetes. J Med Chem 2010 Jan 14 1
50 20018812 Tirucallic acids are novel pleckstrin homology domain-dependent Akt inhibitors inducing apoptosis in prostate cancer cells. Mol Pharmacol 2010 Mar 1