UNII-042A8N37WH






729 Article(s)
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1 9412500 Isoform-specific effect of apolipoprotein E on cell survival and beta-amyloid-induced toxicity in rat hippocampal pyramidal neuronal cultures. J Neurosci 1998 Jan 1 4
2 9427376 Estrogens stabilize mitochondrial function and protect neural cells against the pro-apoptotic action of mutant presenilin-1. Neuroreport 1997 Dec 1 1
3 9579682 Mitogen-activated protein kinases activated by lipopolysaccharide and beta-amyloid in cultured rat microglia. Neuroreport 1998 Mar 30 2
4 9614222 beta-Amyloid fibrils activate parallel mitogen-activated protein kinase pathways in microglia and THP1 monocytes. J Neurosci 1998 Jun 15 5
5 9651495 Enhanced efficiency of a targeted fusogenic peptide. Biochim Biophys Acta 1998 Jun 24 1
6 10094147 Beta-amyloid levels predict cholinesterase activity in human cerebrospinal fluid. Neuroreport 1999 Jan 18 1
7 10214973 Inhibition of beta-amyloid cytotoxicity by midkine. Neurosci Lett 1998 Oct 2 1
8 10217271 Inhibitors of V-type ATPases, bafilomycin A1 and concanamycin A, protect against beta-amyloid-mediated effects on 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) reduction. J Neurochem 1999 May 1
9 10526177 Inhibition of tau phosphorylating protein kinase cdk5 prevents beta-amyloid-induced neuronal death. FEBS Lett 1999 Oct 15 1
10 10759182 Amyloid beta-induced neuronal death is bax-dependent but caspase-independent. J Neuropathol Exp Neurol 2000 Apr 1
11 10869810 Induction of rat L-phosphoserine phosphatase by amyloid-beta (1-42) is inhibited by interleukin-11. Neurosci Lett 2000 Jul 7 1
12 10891607 Antisense DNA against calcineurin facilitates memory in contextual fear conditioning by lowering the threshold for hippocampal long-term potentiation induction. Neuroscience 2000 1
13 11027672 The presenilin 1 C92S mutation increases abeta 42 production. Biochem Biophys Res Commun 2000 Oct 14 1
14 11040402 Beta-amyloid-induced activation of caspase-3 in primary cultures of rat neurons. Mech Ageing Dev 2000 Oct 20 1
15 11059902 Toxic effect of the beta-amyloid precursor protein C-terminus fragment and Na+/Ca2+ gradients. Neuroreport 2000 Oct 20 1
16 11179458 Characterization of recombinant, soluble beta-secretase from an insect cell expression system. Mol Pharmacol 2001 Mar 1
17 11238717 Central beta-amyloid peptide-induced peripheral interleukin-6 responses in mice. J Neurochem 2001 Mar 2
18 11262183 A Cdk5-p35 stable complex is involved in the beta-amyloid-induced deregulation of Cdk5 activity in hippocampal neurons. Exp Cell Res 2001 Apr 1 1
19 11278111 Neuroprotective effects of estrogen against beta-amyloid toxicity are mediated by estrogen receptors in cultured neuronal cells. Neurosci Lett 2001 Apr 13 2
20 11337485 Degradation of the Alzheimer's amyloid beta peptide by endothelin-converting enzyme. J Biol Chem 2001 Jul 6 3
21 11356308 beta-amyloid induces caspase-dependent early neurotoxic change in PC12 cells: correlation with H2O2 neurotoxicity. Neurosci Lett 2001 Jun 1 1
22 11524148 Reduction of cortical amyloid beta levels in guinea pig brain after systemic administration of physostigmine. Neurosci Lett 2001 Sep 7 1
23 11532428 Progressive brain dysfunction following intracerebroventricular infusion of beta(1-42)-amyloid peptide. Brain Res 2001 Sep 7 1
24 11701763 Vaccination with soluble Abeta oligomers generates toxicity-neutralizing antibodies. J Neurochem 2001 Nov 1
25 11711876 Brain prolyl oligopeptidase activity is associated with neuronal damage rather than beta-amyloid accumulation. Neuroreport 2001 Oct 29 1
26 11741401 Generation and characterization of immortalized human microglial cell lines: expression of cytokines and chemokines. Neurobiol Dis 2001 Dec 6
27 11829410 Inhibition of catalase activity with 3-amino-triazole enhances the cytotoxicity of the Alzheimer's amyloid-beta peptide. Neurotoxicology 2001 Dec 2
28 11851430 A novel epsilon-cleavage within the transmembrane domain of the Alzheimer amyloid precursor protein demonstrates homology with Notch processing. Biochemistry 2002 Feb 26 1
29 11897097 Induction of cytochrome c-mediated apoptosis by amyloid beta 25-35 requires functional mitochondria. Brain Res 2002 Mar 29 2
30 12028822 Oxidative stress modulates tyrosine kinase receptor A and p75 receptor (low-affinity nerve growth factor receptor) expression in SHSY5Y neuroblastoma cells. Neurol Clin Neurophysiol 2002 4
31 12034804 Are interleukin-1 gene polymorphisms risk factors or disease modifiers in AD? Neurology 2002 May 28 1
32 12038964 Implication of the small GTPase Rac1 in the generation of reactive oxygen species in response to beta-amyloid in C6 astroglioma cells. Biochem J 2002 Sep 15 2
33 12054502 Mechanism of membrane depolarization caused by the Alzheimer Abeta1-42 peptide. Biochem Biophys Res Commun 2002 May 17 1
34 12070348 The aspartate-257 of presenilin 1 is indispensable for mouse development and production of beta-amyloid peptides through beta-catenin-independent mechanisms. Proc Natl Acad Sci U S A 2002 Jun 25 1
35 12105192 Abeta 42-induced increase in neprilysin is associated with prevention of amyloid plaque formation in vivo. J Biol Chem 2002 Sep 20 1
36 12165737 Neuroprotective effect of garlic compounds in amyloid-beta peptide-induced apoptosis in vitro. Med Sci Monit 2002 Aug 2
37 12165795 Additive effects of amyloid beta fragment and interleukin-1beta on interleukin-6 secretion in rat primary glial cultures. Int J Mol Med 2002 Sep 2
38 12182949 The neuropeptide PACAP attenuates beta-amyloid (1-42)-induced toxicity in PC12 cells. Peptides 2002 Aug 2
39 12404514 Modeling Alzheimer's disease immune therapy mechanisms: interactions of human postmortem microglia with antibody-opsonized amyloid beta peptide. J Neurosci Res 2002 Nov 15 1
40 12409609 Confirmation by FRET in individual living cells of the absence of significant amyloid beta -mediated caspase 8 activation. Proc Natl Acad Sci U S A 2002 Nov 12 3
41 12417433 Reduced Th1 and enhanced Th2 immunity after immunization with Alzheimer's beta-amyloid(1-42). J Neuroimmunol 2002 Nov 4
42 12421354 beta-Amyloid peptide induces formation of actin stress fibers through p38 mitogen-activated protein kinase. J Neurochem 2002 Nov 1
43 12423249 Failure of the interaction between presenilin 1 and the substrate of gamma-secretase to produce Abeta in insect cells. J Neurochem 2002 Oct 1
44 12440482 In vitro apolipoprotein E protects human red blood cells against lysis induced by amyloid-beta (AP) fragment 25-35. Amyloid 2002 Jun 3
45 12507730 Involvement of oxidative stress in the enhancement of acetylcholinesterase activity induced by amyloid beta-peptide. Neurosci Res 2003 Jan 1
46 12543059 Pravastatin inhibits pro-inflammatory effects of Alzheimer's peptide Abeta(1-42) in glioma cell culture in vitro. Pharmacol Res 2003 Feb 1
47 12558997 Stabilization of the cyclin-dependent kinase 5 activator, p35, by paclitaxel decreases beta-amyloid toxicity in cortical neurons. J Neurochem 2003 Jan 2
48 12570807 Emerging beta-amyloid therapies for the treatment of Alzheimer's disease. Curr Pharm Des 2003 1
49 12607822 Amyloid beta-peptide (1-42)-induced oxidative stress and neurotoxicity: implications for neurodegeneration in Alzheimer's disease brain. A review. Free Radic Res 2002 Dec 2
50 12643944 Inhibitors of Abeta production: solid-phase synthesis and SAR of alpha-hydroxycarbonyl derivatives. Bioorg Med Chem Lett 2003 Mar 24 1